A riverside walkway with cyclists, a bridge, and modern buildings.

Find Resorts & Hotels with Spas in Greenville, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Greenville Resorts & Hotels with Spas

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Greenville hotels with a spa

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (570 reviews)
"Wonderful"
United States
colleen
The price is ₩466,893
₩528,990 total
includes taxes & fees
Nov 22 - Nov 23
Grand Bohemian Lodge Greenville, Autograph Collection
A wooden deck with a table and chairs, a bench, and a covered area with a view of a house in the background.

2. Swamp Rabbit Inn

Swamp Rabbit Inn
3.0 star property
Greenville Downtown
8.8 out of 10, Excellent, (449 reviews)
"Amazing Property and Close to Dt Greenville!"
United States
Peyton
The price is ₩179,642
₩211,002 total
includes taxes & fees
Nov 12 - Nov 13
Swamp Rabbit Inn
A sign for the Urban Boutique Hotel with the number 536.

3. Urban Boutique Hotel, BW Signature Collection

Urban Boutique Hotel, BW Signature Collection
2.5 star property
Greenville
8.0 out of 10, Very good, (1,001 reviews)
"Super clean and good price, great food right across the street. Breakfast was good with great waffles."
United States
Douglas
The price is ₩97,501
₩107,251 total
includes taxes & fees
Nov 11 - Nov 12
Urban Boutique Hotel, BW Signature Collection
A multi-story hotel with a yellow facade, a covered parking area, and a visible parking sign.

4. Quality Inn & Suites Greenville near downtown

Quality Inn & Suites Greenville near downtown
2.5 star property
Greenville
7.0 out of 10, Good, (791 reviews)
"It was an acceptable place to stay. It was clean."
United States
Steve
The price is ₩89,577
₩98,534 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn & Suites Greenville near downtown
An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

5. Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
3.0 star property
Greenville
9.4 out of 10, Exceptional, (1,094 reviews)
"Great location, clean, and good options."
United States
Jamie
The price is ₩153,394
₩168,734 total
includes taxes & fees
Nov 8 - Nov 9
Drury Inn & Suites Greenville
A modern living room with a fireplace, seating area, and a kitchen in the background.

6. Comfort Suites Greenville Airport

Comfort Suites Greenville Airport
2.5 star property
Greenville
9.2 out of 10, Wonderful, (1,001 reviews)
"One of the best hotels I’ve ever stayed at"
United States
Azalia
The price is ₩118,484
₩134,242 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Suites Greenville Airport
A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

7. Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
2.5 star property
Greenville
9.2 out of 10, Wonderful, (1,596 reviews)
"Great stay"
United States
Rubin
The price is ₩101,810
₩111,991 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Plus Greenville I-385 Inn & Suites
An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

8. Courtyard by Marriott Greenville Mauldin

Courtyard by Marriott Greenville Mauldin
3.0 star property
Greenville
9.2 out of 10, Wonderful, (411 reviews)
"Everyone at this property was real friendly. We enjoyed our stay."
United States
James
The price is ₩159,414
₩175,356 total
includes taxes & fees
Nov 8 - Nov 9
Courtyard by Marriott Greenville Mauldin
An outdoor patio with wicker furniture, a stone fire pit, and a pergola.

9. Staybridge Suites Greenville I-85 Woodruff Road by IHG

Staybridge Suites Greenville I-85 Woodruff Road by IHG
3.0 star property
Greenville
9.2 out of 10, Wonderful, (351 reviews)
"Clean hotel with great staff."
United States
Matthew
The price is ₩206,300
₩226,930 total
includes taxes & fees
Nov 22 - Nov 23
Staybridge Suites Greenville I-85 Woodruff Road by IHG
A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

10. DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
3.0 star property
Greenville
9.2 out of 10, Wonderful, (1,000 reviews)
"Room was clean and well appointed. Always a great stay!"
United States
Jamie
The price is ₩138,330
₩156,728 total
includes taxes & fees
Nov 22 - Nov 23
DoubleTree by Hilton Greenville Woodruff Road
A modern outdoor seating area with a glass-top coffee table, blue sofas, and orange patterned cushions.

11. Tru by Hilton Greenville Woodruff Road

Tru by Hilton Greenville Woodruff Road
2.5 star property
Greenville
9.2 out of 10, Wonderful, (425 reviews)
"amazing property"
United States
Amy
The price is ₩137,321
₩163,713 total
includes taxes & fees
Nov 29 - Nov 30
Tru by Hilton Greenville Woodruff Road
An outdoor patio with a brick fireplace, outdoor kitchen, and seating area.

12. Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
Greenville
9.2 out of 10, Wonderful, (492 reviews)
"Very clean room, AC worked great, comfy bed, and I didn't expect the kitchenette but was pleasantly surprised. I would stay again."
United States
gina
The price is ₩166,881
₩189,076 total
includes taxes & fees
Nov 22 - Nov 23
Residence Inn by Marriott Greenville
An outdoor patio with a wooden pergola, a bar area with stools, and a grill.

13. Homewood Suites by Hilton Greenville

Homewood Suites by Hilton Greenville
3.0 star property
Greenville
9.0 out of 10, Wonderful, (405 reviews)
"We love everything about the hotel"
United States
Julian
The price is ₩167,585
₩189,874 total
includes taxes & fees
Nov 29 - Nov 30
Homewood Suites by Hilton Greenville
A Holiday Inn Express & Suites with a covered entrance and a clear sky.

14. Holiday Inn Express & Suites Greenville-I-85 & Woodruff Rd by IHG

Holiday Inn Express & Suites Greenville-I-85 & Woodruff Rd by IHG
2.5 star property
Greenville
9.0 out of 10, Wonderful, (1,000 reviews)
"Holiday inn is always my to go hotel when traveling! Rooms are big and clean ."
United States
Jammie
The price is ₩153,408
₩173,811 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express & Suites Greenville-I-85 & Woodruff Rd by IHG
A multi-level hotel lobby with a central atrium, multiple dining areas, and a reception desk.

15. Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1,441 reviews)
"It’s a home away from home!"
United States
Shirleen
The price is ₩130,719
₩148,104 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Greenville Golf Resort & Conference Center
A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.

16. Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.
3.0 star property
Greenville
8.8 out of 10, Excellent, (881 reviews)
"Very convenient area to exit and enter Lots of food and entertainment accommodation the available entrance to begin travel is ideal and the amenities were all in good working condition"
United States
Joseph
The price is ₩136,212
₩154,328 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Greenville I-385 - Woodruff Rd.
A white BMW with "BMW Performance Driving School" text on the side, driving on a road with a cloud-covered sky in the background.

17. Greenville Marriott

Greenville Marriott
4.0 star property
Greenville
8.6 out of 10, Excellent, (711 reviews)
"We had a great stay! Rooms were very clean and beds very comfortable!!"
United States
John
The price is ₩162,746
₩184,391 total
includes taxes & fees
Nov 29 - Nov 30
Greenville Marriott
A workspace with two computer monitors, a keyboard, and office chairs. There are shelves with illuminated artwork, including a butterfly, a bird, and a bicycle.

18. Fairfield Inn by Marriott Greenville-Spartanburg Airport

Fairfield Inn by Marriott Greenville-Spartanburg Airport
3.0 star property
Greenville
8.6 out of 10, Excellent, (683 reviews)
"We enjoyed to stay this hotel"
United States
Yukiko
The price is ₩128,495
₩145,586 total
includes taxes & fees
Nov 2 - Nov 3
Fairfield Inn by Marriott Greenville-Spartanburg Airport
A hotel room with a large bed, two bedside lamps, a desk with a telephone, and a chair.

19. Candlewood Suites Greenville by IHG

Candlewood Suites Greenville by IHG
2.5 star property
Greenville
8.8 out of 10, Excellent, (292 reviews)
"The location off Interstate 85N and especially the helpful staff."
United States
Lucy
The price is ₩135,301
₩148,831 total
includes taxes & fees
Nov 6 - Nov 7
Candlewood Suites Greenville by IHG
A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.

20. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
3.0 star property
Greenville
8.8 out of 10, Excellent, (409 reviews)
"Staff was friendly and professional. Parking was always available and property was well maintained."
United States
Sam
The price is ₩130,397
₩147,741 total
includes taxes & fees
Nov 2 - Nov 3
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Greenville

Pool
Hot tub

Top Greenville Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Great breakfast"
Eric 3-night trip
Posted 5 hours ago
Embassy Suites Greenville Golf Resort & Conference Center

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness center and a restaurant. Enjoy a massage at The Spa at Grand Bohemian. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 702 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate, and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.