A riverside walkway with cyclists, a bridge, and modern buildings.

Find Resorts & Hotels with Spas in Greenville, SC

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Check availability on Greenville Resorts & Hotels with Spas

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Greenville hotels with a spa

A spa room with two beds, a mural, and a reception desk.
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.
A modern interior with a fireplace, plush seating, and a stone accent wall.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
₩464,363
₩526,123 total
includes taxes & fees
Nov 15 - Nov 16
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.
A cozy lounge area with leather armchairs, a central table, and a fireplace.
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

2. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
₩218,768
₩291,790 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.
A swimming pool with lounge chairs and a building with balconies.
A reception area with a wooden reception desk, a large abstract painting, and a potted plant.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
₩557,710
₩613,481 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Domestique
A wooden deck with chairs, surrounded by trees with autumn foliage.
A cozy room with a fireplace, a bed, a sofa, and a wooden dresser.
A wooden deck with a spiral glass sculpture, potted plants, and a bench.
A dining table set for two with a view of a forested landscape through large windows.

4. The Orchard Inn

The Orchard Inn
Saluda
  • Enjoy a couples massage or solo Swedish retreat in this peaceful bed & breakfast with gardens and a 24-hour gym.
₩396,844
₩435,532 total
includes taxes & fees
Nov 1 - Nov 2
The Orchard Inn
View all properties

Choose what matters most at spa hotels in Greenville

Pool
Hot tub
Breakfast included
4 stars
Gym

Top Greenville Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"The property was beautiful however our room 303 had a very strong musty smell as soon as you walked into the room as if the carpet had gotten wet maybe. I had to purchase spray to accomidate the odor. Also the pillows was very uncomfortable."
Rhonda 1-night trip
Posted 13 hours ago
Embassy Suites Greenville Golf Resort & Conference Center
Hilton Greenville

Hilton Greenville

8/10 Good
"Bed too firm. Shower not clean. What appeared to be medical wrapper left in accessible shower. Front desk was understanding and offered me minimal points for my stay to my HH account. Breakfast was fresh. Overpriced for eggs and bacon. But good. Smells great as you walk in. Probably a one-off with room and of course I got that room!"
Nina 1-night trip
Posted 14 hours ago
Hilton Greenville

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness center and a restaurant. Enjoy a massage at The Spa at Grand Bohemian. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 702 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate, and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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