Top Main Street Hotels

Ann Arbor, Michigan, USA Downtown Panorama

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Where to stay in Main Street

Find the best Main Street areas and neighborhoods for the activities you enjoy most.

South Central

While visiting South Central, you might make a stop by sights like Yost Ice Arena and Michigan Stadium.

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Downtown

While visiting Downtown, you might make a stop by sights like Ann Arbor Hands On Museum and Kempf House Museum.

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Aerial View of Burton Memorial Tower in Ann Arbor Campus

Old West Side

While there might not be top attractions in Old West Side, you can explore the larger area and discover places like Ann Arbor Hands On Museum and University of Michigan Museum of Art.

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Aerial View of Railway Bridge and Dam on Huron River in Autumn

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Buhr Park and Cobblestone Farm are top sights worth seeing.

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Central Campus Medical

If you're spending some time in Central Campus Medical, Exhibit Museum of Natural History at the University Of Michigan and Hill Auditorium are top sights worth seeing.

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Top Main Street Hotel Reviews

Ann Arbor Regent Hotel & Suites

10/10 Excellent

"Clean room. Nice staff. Easy parking"

Saint John's Resort

8/10 Good

"We often travel to Michigan to visit family and staying at St. John's Resort was on the wish list. This most recent visit we booked a couple nights of the trip. This particular weekend St. John's was dealing with two large wedding celebrations but staff were still available to us for questions. Their famous steakhouse was prohibitively expensive for us so we tried a small meal for brunch. The server was attentive to us and all the tables he was tending. The food was good but nothing exceptional. The room was immaculate and well stocked with supplies. However, compared to the Hilton we'd just come from this room was smaller. The best aspect of the room was the quiet HVAC system. We were not awakened by a noisy heating/cooling unit; this was completely quiet. The bed linens were OK (the standard for us was Kingsmill Resort in Williamsburg, Virginia.). If you're picky about having a firm pillow. pack your own. St. John's pillows are medium firmness. It wasn't terrible, we just had higher expections and turned out to be just OK."

Wyndham Garden Ann Arbor

10/10 Excellent

"The room was clean and comfortable. There was a comfy chair, a desk area with chair and an extra blanket. The staff were all very helpful. Breakfast was not continental, but a full hot breakfast with sausage, eggs, tater tots and waffles. There was a lovely stone bar, and a decent dinner menu. The pool was popular. Many comfortable places to sit downstairs. Good parking."

Red Roof Inn Ann Arbor - U of Michigan South

6/10 Okay

"The lady that checked us in was not friendly at all…I almost felt like she didn’t want us there (ha). She then charged us $27 to check in 2 hours early. That was silly. After I checked my brother in, we went to Vanguard and checked into our hotel and no early check in fees. But I guess you get what you pay for! The hotel itself was pretty clean. The exterior was still old and run down looking."

Frequently asked questions

What is Main Street like?

Main Street is a neighborhood that travelers like for its art, university setting, and entertainment choices.

If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the top deals on offer in Main Street.

Where can I learn more about changing or cancelling my trip to Main Street?

To find more details about updating your trip to Main Street or cancelling it, go to https://www.expedia.com/service/.

What is there to do around this Ann Arbor neighborhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center, and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

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Our top choices for Main Street hotels

Ann Arbor Regent Hotel & Suites

Holiday Inn Express & Suites Plymouth - Ann Arbor Area by IHG

Spark by Hilton Plymouth

Hilton Garden Inn Plymouth

Fairfield Inn and Suites by Marriott Detroit Canton

Hampton Inn & Suites Detroit-Canton

Wingate by Wyndham Brighton

Home2 Suites by Hilton Northville Detroit

Hampton Inn & Suites Ypsilanti

Hyatt Place Ann Arbor

TownePlace Suites by Marriott Detroit Belleville

Holiday Inn Express Hotel & Suites Belleville by IHG

Spark by Hilton Ann Arbor South

Courtyard By Marriott Ann Arbor

La Quinta Inn by Wyndham Detroit Canton

Hampton Inn Hotel Detroit/Belleville-Airport Area

Extended Stay America Suites Detroit Canton

Saint John's Resort

Wyndham Garden Ann Arbor

Fairfield Inn & Suites by Marriott Ann Arbor Ypsilanti

Where to stay in Main Street

South Central

Downtown

Old West Side

Bryant Pattengill East

Central Campus Medical

Top Main Street Hotel Reviews

Ann Arbor Regent Hotel & Suites

Frequently asked questions

Explore a world of travel with Expedia