The Best Hotels Closest to Mary Bird Perkins Cancer Center in Natchez for 2026

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Our top choices for Mary Bird Perkins Cancer Center hotels

A large, two-story building with a symmetrical facade, surrounded by trees and illuminated by string lights.

A bar area with a bartender pouring a drink into a glass, a shelf with various liquor bottles, and two glasses with a red drink on the counter.

A formal dining room with a long table set for a meal, surrounded by upholstered chairs.

A grand room with a chandelier, a piano, a sofa, and a table with a vase of flowers.

1. Monmouth Historic Inns and Gardens

3.1 km from Mary Bird Perkins Cancer Center

Diana

₩192,132

₩244,025 total

includes taxes & fees

Oct 31 - Nov 1

A large, symmetrical building with a central entrance flanked by columns, surrounded by a well-maintained lawn.

A restaurant with brick walls, wooden beams, and plaid chairs. Tables are set with white tablecloths and silverware.

A porch with white rocking chairs and a black wrought iron railing.

A room with a fireplace, ornate chairs, a round table, and a large mirror.

2. Dunleith Historic Inn

2.9 km from Mary Bird Perkins Cancer Center

Herbert

₩189,154

₩254,768 total

includes taxes & fees

Nov 1 - Nov 2

A reception area with a wooden reception desk, a black circular wall art, and a modern ceiling design.

A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

A bathroom with a large mirror, a sink, and a trash bin.

A modern kitchen with blue cabinets, a central island, and a seating area with round tables and chairs.

3. Excellent Inn & Suites

0.2 km from Mary Bird Perkins Cancer Center

Mary

₩126,087

₩141,378 total

includes taxes & fees

Oct 18 - Oct 19

A building with a central entrance, columns, and a balcony with railings.

A hotel room with two beds, a bench, a nightstand, and a lamp.

A reception area with two patterned armchairs, a small table with a lamp, and a potted plant.

A covered outdoor seating area with a table and benches, surrounded by trees and a building with a porch.

4. Days Inn by Wyndham Natchez

0.7 km from Mary Bird Perkins Cancer Center

Rosia

₩93,011

₩104,982 total

includes taxes & fees

Oct 21 - Oct 22

A hallway with a stone fountain, green plants, and a statue.

A cozy living room with a television, a coffee table, wicker furniture, and a staircase.

A two-story brick building with white columns and a balcony, surrounded by a white fence.

A dining area with a chandelier, a fireplace, and a staircase.

5. Choctaw Hall Bed and Breakfast

4.5 km from Mary Bird Perkins Cancer Center

Jean

₩200,538

₩223,261 total

includes taxes & fees

Oct 26 - Oct 27

A two-story house with a covered porch, brick exterior, and white columns.

A dining room with a round table set for six, surrounded by wooden chairs.

A traditional living room with a fireplace, a bookshelf, and a chandelier.

A spacious living room with a wooden coffee table, a sofa, and a dining table. There are potted plants and a chandelier.

6. Concord Quarters

4.4 km from Mary Bird Perkins Cancer Center

Justin

₩134,492

₩150,610 total

includes taxes & fees

Oct 19 - Oct 20

A balcony with a sofa, a small table, and a stool. There is a view of buildings and a sunset in the background.

A view through a window with a street scene, including buildings and a street lamp.

A living room with a coffee table, two armchairs, a painting on the wall, a kitchen area with white cabinets, and a wooden table.

A building with a black awning, a sign reading "Nathans Manor," and a number "600" on the door. There are outdoor tables and chairs, and a tree is visible.

7. Natchez Manor Bed & Breakfast

4 km from Mary Bird Perkins Cancer Center

Jill S.

₩184,447

₩205,568 total

includes taxes & fees

Oct 19 - Oct 20

A large, two-story house with a prominent tree in front, white exterior, and a covered porch.

A four-poster bed with a canopy, a dresser, a chair, and a decorative vase.

A living room with a sofa, a glass coffee table, a patterned rug, a wooden chair, and a kitchen in the background.

A room with a fireplace, a large mirror, and a red armchair.

8. Brandon Hall Plantation

16.2 km from Mary Bird Perkins Cancer Center

Elizabeth

₩346,171

₩370,401 total

includes taxes & fees

Oct 19 - Oct 20

A brown leather armchair with a cushion that has text, positioned in front of a window with white curtains.

A room with two upholstered chairs, a small table with a lamp, and a window with a view of greenery outside.

A corridor with a closed door labeled "Carriage House," a wicker chair, and a hanging lantern.

A dining area with a table set for four, surrounded by white chairs, large windows with a view of greenery, and a chandelier.

9. The Natchez Pearl

4.3 km from Mary Bird Perkins Cancer Center

John

₩166,715

₩325,491 total

includes taxes & fees

Oct 20 - Oct 21

A two-story house with a front porch, a brick pathway, and a large tree.

A spacious living room with a large, ornate chandelier, a patterned area rug, and classic furniture including a sofa and armchairs.

A room with a wooden dresser, a large ornate mirror, a vase with flowers, a framed painting, and a chair.

A spacious living room with hardwood floors, a chandelier, a fireplace, and a dining area in the background.

10. The Beaumont House

3.7 km from Mary Bird Perkins Cancer Center

Sherrill

₩225,488

₩250,706 total

includes taxes & fees

Oct 18 - Oct 19

A two-story building with a prominent entrance and large windows.

A hotel room with two beds, a sitting area with a chair and table, a bathroom visible through an open door, and a large mirror.

A dining area with tables and chairs, large windows with curtains, and a patterned carpet.

An outdoor patio area with multiple tables and chairs, surrounded by potted plants and a brick building in the background.

11. The Guest House Historic Mansion

4.2 km from Mary Bird Perkins Cancer Center

Jodie

₩151,905

₩169,765 total

includes taxes & fees

Nov 3 - Nov 4

A swimming pool with a statue on the left, surrounded by neatly trimmed hedges and trees.

A four-poster bed with a canopy, a sitting area with a small table and chairs, and a large mirror on the wall.

A white colonial-style house with a porch, surrounded by a garden with pink flowers.

A garden with a brick pathway, white benches, and a fountain.

12. The Burn Bed and Breakfast

4.5 km from Mary Bird Perkins Cancer Center

JOHN

₩197,469

₩219,885 total

includes taxes & fees

Oct 19 - Oct 20

A brick building with a green awning labeled "GRAND HOTEL".

A spacious living room with a fireplace, a staircase, and a dining area.

A spacious bar area with multiple seating options, a bar counter with a variety of bottles, and large windows providing natural light.

A sign for the Grand Hotel Natchitoches with a brick archway and a garden with colorful flowers.

13. Natchez Grand Hotel & Suites on the River

4.5 km from Mary Bird Perkins Cancer Center

Tamara

₩167,408

₩219,016 total

includes taxes & fees

Nov 1 - Nov 2

A modern restaurant with a long counter, multiple seating areas, and a distinctive blue brick wall.

A modern living room with a fireplace, two armchairs, a coffee table, and a large window with curtains.

A modern hotel lobby with a seating area, a desk, and a decorative light fixture.

A modern lobby with a sofa, chairs, and a coffee table.

14. The Bridges Hotel

4.1 km from Mary Bird Perkins Cancer Center

Thomas

₩123,938

₩139,001 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, two bedside lamps, a flat-screen TV, a dresser, and a patterned carpet.

A self-service beverage station with refrigerated drink dispensers, a neon sign, and a snack shelf.

A white building with a sign reading 'Hampton Inn & Suites.'

A conference room with tables and chairs, a whiteboard, a TV, and a window with blinds.

15. Hampton Inn & Suites Natchez

3.9 km from Mary Bird Perkins Cancer Center

Bobbi

₩216,629

₩240,960 total

includes taxes & fees

Oct 31 - Nov 1

A patio with a fire pit, outdoor seating, and a view of a park.

A modern kitchenette with a microwave, oven, and sink. There is a sofa with cushions and a chair in the living area.

A townhouse hotel with a modern design, featuring a covered entrance and a well-maintained garden area.

A modern kitchen with dark wood cabinets, a herringbone floor pattern, and a central island with a red bowl of fruit.

16. TownePlace Suites by Marriott Vidalia Riverfront

5.4 km from Mary Bird Perkins Cancer Center

Lorenza

₩225,688

₩279,288 total

includes taxes & fees

Nov 2 - Nov 3

A spacious living area with a modern sofa set, a black and white rug, and large windows offering a view of the outdoors.

A modern room with a pool table, white chairs, a ceiling fan, and large windows offering a view of the city.

A swimming pool with lounge chairs and a building with multiple floors and large windows.

A modern living room with a sectional sofa, a flat-screen TV mounted on a red wall, and a large window offering a view of the outdoors.

17. Magnolia Hotel, BW Signature Collection

4.1 km from Mary Bird Perkins Cancer Center

Carol

₩180,311

₩201,012 total

includes taxes & fees

Oct 25 - Oct 26

A hotel lobby with a fireplace, seating area, and a reception desk.

A hotel room with a large bed, a sofa, a desk with a lamp, and a framed picture on the wall.

A Holiday Inn Express & Suites with a large parking lot, a building entrance, and a signboard.

A modern kitchen with wooden cabinets, a white countertop, and a coffee machine.

18. Holiday Inn Express Hotel & Suites Natchez South by IHG

3.8 km from Mary Bird Perkins Cancer Center

thomas

₩186,795

₩208,143 total

includes taxes & fees

Oct 27 - Oct 28

A terrace with lounge chairs and umbrellas overlooking a river.

An indoor swimming pool with clear water, tiled walls, and a sunlit room with windows and lounge chairs.

A spacious living room with a leather sofa, two patterned armchairs, a wooden coffee table, and a decorative plant arrangement. Large windows with curtains provide natural light and a view.

A room with a large window, a patterned rug, and a wooden chair.

19. Clarion Suites Vidalia Riverfront

5.4 km from Mary Bird Perkins Cancer Center

Dwight

₩150,103

₩173,744 total

includes taxes & fees

Oct 26 - Oct 27

A Red Carpet Inn with a sign indicating free hot breakfast, a Cash Saver nearby, and a parking area.

A hotel lobby with a reception desk, chairs, a small table, and a potted plant.

A hotel room with two beds, each with green bedding, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A small office with a desk, chair, laptop, potted plant, framed picture, and a shelf with magazines.

20. Red Carpet Inn

4.3 km from Mary Bird Perkins Cancer Center

alison

₩108,074

₩121,550 total

includes taxes & fees

Oct 20 - Oct 21

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Compare popular hotels close to Mary Bird Perkins Cancer Center

Property	Property class	Guest rating
Monmouth Historic Inns and Gardens	9.4 Exceptional 727 reviews	View
Dunleith Historic Inn	8.8 Excellent 560 reviews	View
Excellent Inn & Suites	8.0 Very good 327 reviews	View
Days Inn by Wyndham Natchez	6.6 1,003 reviews	View
Choctaw Hall Bed and Breakfast	10.0 Exceptional 398 reviews	View

Top Mary Bird Perkins Cancer Center Hotel Reviews

The Guest House Historic Mansion

10/10 Excellent

"Cute and quaint! Staff was amazing, so kind and helpful with suggestions on places to eat, what was going on in time, etc. Breakfast was great! We would stay there again."

Days Inn by Wyndham Natchez

10/10 Excellent

"Meet a cook originally from New Orleans who had a great personality and a wonderful cook. She's an older lady with a people's spirit i.e. smiles, greets everyone and a hard worker ❤️ 💙"

Excellent Inn & Suites

8/10 Good

"Clean room"

Natchez Grand Hotel

10/10 Excellent

"Good stay. Got a room upgrade"

The Hotel Vue

8/10 Good

"There need to be a microwave in the rooms. I wasn’t able to heat up my food. Other than that everything was good."

Red Carpet Inn

10/10 Excellent

"Best value I’ve found in Natchez. Been here many times and will return. The best value for lodging you’ll find in 2026 and beyond, clean and comfortable in a safe and welcoming environment."

Monmouth Historic Inns and Gardens

10/10 Excellent

"The staff was wonderful. Excellent breakfast."

Hampton Inn & Suites Natchez

10/10 Excellent

"Hampton Inn is yet to let me down . Friendly staff, good breakfast , good location , good house keeping. It’s just good ."

Linden Historic Bed & Breakfast

10/10 Excellent

"Beautiful cottage decorated for the holidays, in a quiet residential neighborhood but close to town. Perfect for our family Christmas trip. "

Other attractions near Mary Bird Perkins Cancer Center

Longwood

9.4/10 (312 reviews)

You can find out about the history of Natchez with a stop at Longwood. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Grand Village of the Natchez Indians

You can spend time browsing the exhibits at Grand Village of the Natchez Indians during your travels in Natchez. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

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Elms Court

10.0/10 (5 reviews)

You can find out about the history of Natchez with a stop at Elms Court. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Alcorn State University

Walk around the campus at Alcorn State University during your stay in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Melrose

9.0/10 (133 reviews)

Find out about the history of Natchez when you take a trip to Melrose. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

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Natchez National Historical Park

9.2/10 (331 reviews)

Explore the great outdoors at Natchez National Historical Park, a lovely green space in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Auburn Museum & Historic Home

9.8/10 (9 reviews)

You can browse the exhibits at Auburn Museum & Historic Home, a museum with a story of its own, during your trip to Natchez. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

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Martin Performing Arts Center

Enjoy an outing to Martin Performing Arts Center during your stay in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Frequently asked questions

What's the area like around Mary Bird Perkins Cancer Center?

Mary Bird Perkins Cancer Center is located in Natchez. This historic area is known for its beautiful river views and array of dining options. You'll find 139 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Mary Bird Perkins Cancer Center?

Adjacent to Mary Bird Perkins Cancer Center, Excellent Inn & Suites is one of the top choices for your stay based on our traveler data. Another good choice is Days Inn by Wyndham Natchez, located just 0.4 mi (0.7 km) away.

How many hotels are there close to Mary Bird Perkins Cancer Center?

Expedia has 139 hotels and other accommodations a few miles from Mary Bird Perkins Cancer Center.

If I need to cancel the hotel reservation for my stay near Mary Bird Perkins Cancer Center, will I receive a refund?

Yes, most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best deals available near Mary Bird Perkins Cancer Center.

Where can I learn more about changing or cancelling my trip in the area near Mary Bird Perkins Cancer Center?

For additional details about changing or cancelling your stay near Mary Bird Perkins Cancer Center, go to https://www.expedia.com/service/.

What can I see and do near Mary Bird Perkins Cancer Center?

Rosalie Mansion, Rhythm Night Club Museum, and Auburn Museum & Historic Home feature a variety of fascinating exhibits to see while you're in town. Longwood, Natchez National Historical Park, and Magnolia Hall are monuments to see when you're exploring the area around Mary Bird Perkins Cancer Center. For cultural attractions near Mary Bird Perkins Cancer Center, head to Natchez City Auditorium, Stratton Chapel Gallery, and William Johnson House Museum.

Find hotels near Mary Bird Perkins Cancer Center, Natchez from ₩104,982

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Our top choices for Mary Bird Perkins Cancer Center hotels

1. Monmouth Historic Inns and Gardens

2. Dunleith Historic Inn

3. Excellent Inn & Suites

4. Days Inn by Wyndham Natchez

5. Choctaw Hall Bed and Breakfast

6. Concord Quarters

7. Natchez Manor Bed & Breakfast

8. Brandon Hall Plantation

9. The Natchez Pearl

10. The Beaumont House

11. The Guest House Historic Mansion

12. The Burn Bed and Breakfast

13. Natchez Grand Hotel & Suites on the River

14. The Bridges Hotel

15. Hampton Inn & Suites Natchez

16. TownePlace Suites by Marriott Vidalia Riverfront

17. Magnolia Hotel, BW Signature Collection

18. Holiday Inn Express Hotel & Suites Natchez South by IHG

19. Clarion Suites Vidalia Riverfront

20. Red Carpet Inn

Compare popular hotels close to Mary Bird Perkins Cancer Center

Top Mary Bird Perkins Cancer Center Hotel Reviews

The Guest House Historic Mansion

Days Inn by Wyndham Natchez

Excellent Inn & Suites

Natchez Grand Hotel

The Hotel Vue

Red Carpet Inn

Monmouth Historic Inns and Gardens

Hampton Inn & Suites Natchez

Linden Historic Bed & Breakfast

Other attractions near Mary Bird Perkins Cancer Center

Longwood

Grand Village of the Natchez Indians

Elms Court

Alcorn State University

Melrose

Natchez National Historical Park

Auburn Museum & Historic Home

Martin Performing Arts Center

Frequently asked questions