The Best Hotels Closest to Mary Bird Perkins Cancer Center in Natchez for 2026

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Our top choices for Mary Bird Perkins Cancer Center hotels

A large, two-story building with a symmetrical facade, surrounded by trees and illuminated by string lights.

A formal dining room with a long table set for a meal, surrounded by upholstered chairs.

A bar area with a bartender pouring a drink into a glass, a shelf with various liquor bottles, and two glasses with a red drink on the counter.

A garden pathway leading to a white archway with a sign, surrounded by lush greenery and potted plants.

1. Monmouth Historic Inns and Gardens

3.1 km from Mary Bird Perkins Cancer Center

Victor

₩193,009

₩245,138 total

includes taxes & fees

Oct 31 - Nov 1

A large, symmetrical building with a central entrance flanked by columns, surrounded by a well-maintained lawn.

A room with a brick fireplace, two wall-mounted sconces, a grey armchair, a bedside table, and a floor lamp.

A porch with white rocking chairs and a black wrought iron railing.

A restaurant with brick walls, wooden beams, and plaid chairs. Tables are set with white tablecloths and silverware.

2. Dunleith Historic Inn

2.9 km from Mary Bird Perkins Cancer Center

Dan

₩158,347

₩221,094 total

includes taxes & fees

Oct 19 - Oct 20

A reception area with a wooden reception desk, a black circular wall art, and a modern ceiling design.

A motel with a blue and white exterior, a gas station, and a parking lot.

A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

A modern kitchen with blue cabinets, a central island, and a seating area with round tables and chairs.

3. Excellent Inn & Suites

0.2 km from Mary Bird Perkins Cancer Center

Mary

₩114,599

₩143,497 total

includes taxes & fees

Oct 9 - Oct 10

A building with a central entrance, columns, and a balcony with railings.

A hotel room with two beds, a bench, a nightstand, and a lamp.

A covered outdoor seating area with a table and benches, surrounded by trees and a building with a porch.

4. Days Inn by Wyndham Natchez

0.7 km from Mary Bird Perkins Cancer Center

Glynn

₩93,435

₩105,459 total

includes taxes & fees

Oct 21 - Oct 22

A hallway with a stone fountain, green plants, and a statue.

A cozy living room with a television, a coffee table, wicker furniture, and a staircase.

A two-story brick building with white columns and a balcony, surrounded by a white fence.

A covered outdoor corridor with a brick floor, white walls, a white railing, a table with chairs, a bench, and a hanging light fixture.

5. Choctaw Hall Bed and Breakfast

4.5 km from Mary Bird Perkins Cancer Center

JEANIE

₩201,453

₩224,279 total

includes taxes & fees

Oct 5 - Oct 6

A covered porch with a white railing, a fountain, and a lawn with various plants.

A two-story brick house with a front porch, white columns, and a central door.

A dining table set with plates, bowls, cutlery, and glasses, indicating a meal setting.

A room with a pool table, a fireplace, and large windows.

6. Stone House Musical B&B

3.5 km from Mary Bird Perkins Cancer Center

Nancy

₩219,816

₩244,478 total

includes taxes & fees

Oct 6 - Oct 7

A large, two-story house with a prominent tree in front, white exterior, and a covered porch.

A four-poster bed with a canopy, a dresser, a chair, and a decorative vase.

A room with a fireplace, a large mirror, and a red armchair.

A dining table with a chessboard, a potted plant, and leather chairs in a room with a bookshelf and a lamp in the background.

7. Brandon Hall Plantation

16.2 km from Mary Bird Perkins Cancer Center

Elizabeth

₩332,940

₩356,249 total

includes taxes & fees

Oct 5 - Oct 6

A two-story house with a porch, a white picket fence, and an American flag.

A porch with a bench and two rocking chairs, a white railing, and a view of a brick wall and trees.

A bedroom with a wooden panel wall, a bed with a quilt, and framed pictures.

A dining room with a chandelier, a fireplace, and a painting on the wall.

8. Riverboat Bed & Breakfast

4.3 km from Mary Bird Perkins Cancer Center

Christopher

₩223,838

₩248,902 total

includes taxes & fees

Oct 6 - Oct 7

A balcony with a sofa, a small table, and a stool. There is a view of buildings and a sunset in the background.

A cozy outdoor seating area with a sofa, coffee table, and chairs.

A living room with a coffee table, two armchairs, a painting on the wall, a kitchen area with white cabinets, and a wooden table.

A building with a black awning, a sign reading "Nathans Manor," and a number "600" on the door. There are outdoor tables and chairs, and a tree is visible.

9. Natchez Manor Bed & Breakfast

4 km from Mary Bird Perkins Cancer Center

Jill S.

₩185,288

₩206,497 total

includes taxes & fees

Oct 6 - Oct 7

A two-story house with a front porch, a brick pathway, and a large tree.

A spacious living room with hardwood floors, a chandelier, a fireplace, and a dining area in the background.

A formal dining room with a round table set for four, surrounded by ornate chairs.

A room with a wooden dresser, a large ornate mirror, a vase with flowers, a framed painting, and a chair.

10. The Beaumont House

3.7 km from Mary Bird Perkins Cancer Center

Sherrill

₩208,396

₩231,917 total

includes taxes & fees

Oct 5 - Oct 6

A two-story Victorian-style house with a wrap-around porch, a balcony, and a well-maintained front yard.

A house with a porch, surrounded by a garden with various flowers.

A formal dining room with a fireplace, ornate furniture, and a well-set dining table.

A grand staircase with a white balustrade, a chandelier, and a decorative wall with framed pictures.

11. Devereaux Shields House

4.5 km from Mary Bird Perkins Cancer Center

Robert

₩233,204

₩260,545 total

includes taxes & fees

Oct 5 - Oct 6

A two-story building with a prominent entrance and large windows.

A dining area with tables and chairs, large windows with curtains, and a patterned carpet.

A balcony with a green cushion and a metal chair, overlooking a cityscape with buildings and a cloudy sky.

A hotel room with two beds, a sitting area with a chair and table, a bathroom visible through an open door, and a large mirror.

12. The Guest House Historic Mansion

4.2 km from Mary Bird Perkins Cancer Center

Karen

₩162,309

₩181,222 total

includes taxes & fees

Nov 3 - Nov 4

A spacious living room with hardwood floors, a chandelier, a floral rug, and a dining area with a table and chairs.

A covered porch with white columns, a red patterned rug, and two white chairs.

A bedroom with a large bed, a tufted headboard, and a patterned bedspread. There are two bedside tables with lamps and a framed picture above the bed.

A dining room with a chandelier, wooden furniture, and large windows with curtains.

13. The King's Daughters Bed and Breakfast

6 km from Mary Bird Perkins Cancer Center

Margaret

₩233,032

₩259,021 total

includes taxes & fees

Nov 1 - Nov 2

A brick building with a green awning labeled "GRAND HOTEL".

A cozy living room with a sofa, armchairs, a coffee table, and a dining area with chairs and a table. Large windows with curtains provide natural light and views.

A sign for the Grand Hotel Natchitoches with a brick archway and a garden with colorful flowers.

A spacious living room with a fireplace, a staircase, and a dining area.

14. Natchez Grand Hotel & Suites on the River

4.5 km from Mary Bird Perkins Cancer Center

April

₩186,568

₩240,907 total

includes taxes & fees

Oct 5 - Oct 6

A deck with two chairs and a table, overlooking a river and a sunset.

A four-poster bed with a patterned bedspread, a red canopy, and a nightstand with a lamp.

A bathroom with a white shower curtain, a white sink with a large bowl, a toilet, and a mirror with a wooden frame.

A pool area with statues, a white fence, and a sunset view.

15. Weymouth Hall B&B

5.6 km from Mary Bird Perkins Cancer Center

Harley

₩167,194

₩186,595 total

includes taxes & fees

Oct 5 - Oct 6

A hotel lobby with a dining area, seating arrangements, and large windows.

A gym with weightlifting equipment, cardio machines, and a blue exercise ball.

A modern hotel with a flat roof, multiple windows, and a prominent sign.

A hotel room with a bed, desk, TV, and seating area.

16. Hampton Inn & Suites Natchez

3.9 km from Mary Bird Perkins Cancer Center

Bobbi

₩207,726

₩231,180 total

includes taxes & fees

Oct 31 - Nov 1

A modern restaurant with a long counter, multiple seating areas, and a distinctive blue brick wall.

A modern hotel room with a large bed, two bedside tables, a nightstand, a desk, and a chair.

A modern lobby with a sofa, chairs, and a coffee table.

A modern living room with a fireplace, two armchairs, a coffee table, and a large window with curtains.

17. The Bridges Hotel

4.1 km from Mary Bird Perkins Cancer Center

Arthur

₩124,504

₩139,636 total

includes taxes & fees

Oct 11 - Oct 12

A swimming pool with a statue on the left, surrounded by neatly trimmed hedges and trees.

A brick gate with a sign reading "Guest & Tour Entrance."

A white colonial-style house with a porch, surrounded by a garden with pink flowers.

A four-poster bed with a canopy, a sitting area with a small table and chairs, and a large mirror on the wall.

18. The Burn Bed and Breakfast

4.5 km from Mary Bird Perkins Cancer Center

MELISSA

₩198,370

₩220,887 total

includes taxes & fees

Oct 19 - Oct 20

A patio with a fire pit, outdoor seating, and a view of a park.

A gym with treadmills, elliptical machines, and free weights.

A townhouse hotel with a modern design, featuring a covered entrance and a well-maintained garden area.

A modern kitchen with dark wood cabinets, a herringbone floor pattern, and a central island with a red bowl of fruit.

19. TownePlace Suites by Marriott Vidalia Riverfront

5.4 km from Mary Bird Perkins Cancer Center

Shannon

₩232,415

₩287,614 total

includes taxes & fees

Oct 22 - Oct 23

A terrace with lounge chairs and umbrellas overlooking a river.

A spacious living room with a leather sofa, two patterned armchairs, a wooden coffee table, and a decorative plant arrangement. Large windows with curtains provide natural light and a view.

A room with a large window, a patterned rug, and a wooden chair.

A hotel room with two beds, a desk, a television, and a view of the outdoors.

20. Clarion Suites Vidalia Riverfront

5.4 km from Mary Bird Perkins Cancer Center

Dwight

₩150,788

₩174,538 total

includes taxes & fees

Oct 11 - Oct 12

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Compare popular hotels close to Mary Bird Perkins Cancer Center

Property	Property class	Guest rating
Monmouth Historic Inns and Gardens	9.4 Exceptional 726 reviews	View
Dunleith Historic Inn	8.8 Excellent 555 reviews	View
Excellent Inn & Suites	8.0 Very good 322 reviews	View
Days Inn by Wyndham Natchez	6.6 1,000 reviews	View
Choctaw Hall Bed and Breakfast	10.0 Exceptional 395 reviews	View

Top Mary Bird Perkins Cancer Center Hotel Reviews

Natchez Grand Hotel & Suites On the River

8/10 Good

"Nice hotel right on the Mississippi River. Good breakfast. Dinner at Slick Rick’s was great. Only minus was the door to our room was difficult to open and close-had to yank and slam it."

The Guest House Historic Mansion

10/10 Excellent

"It was a nice surprise after a long day on the road. Very friendly and helpful staff"

Excellent Inn & Suites

10/10 Excellent

"Location was great, breakfast was good, and staff was helpful and friendly."

Holiday Inn Express Hotel & Suites Natchez South by IHG

8/10 Good

"Good location. Quiet. Room was clean and comfortable"

Monmouth Historic Inns and Gardens

8/10 Good

"Love the historic architecture. Nice staff. Good breakfast. Dinner at the restaurant was very good. Our room needed a deep clean. (Very dusty drapes and bed crown.) The wallpaper in bathroom is quite stained. But the room was comfortable and very roomy."

The Hotel Vue

10/10 Excellent

"I stayed at the Bridges Hotel. The hotel was beautiful and clean. The staff was so nice and friendly. I got to play with the hotel mascot. Bridges is his name. When I plan another girls trip I will try to get the Bridge Hotel again."

Linden Historic Bed & Breakfast

10/10 Excellent

"Beautiful cottage decorated for the holidays, in a quiet residential neighborhood but close to town. Perfect for our family Christmas trip. "

Other attractions near Mary Bird Perkins Cancer Center

Longwood

9.4/10 (312 reviews)

You can find out about the history of Natchez with a stop at Longwood. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Grand Village of the Natchez Indians

You can spend time browsing the exhibits at Grand Village of the Natchez Indians during your travels in Natchez. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

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Elms Court

10.0/10 (5 reviews)

You can find out about the history of Natchez with a stop at Elms Court. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Alcorn State University

Walk around the campus at Alcorn State University during your stay in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Melrose

9.0/10 (133 reviews)

Find out about the history of Natchez when you take a trip to Melrose. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

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Natchez National Historical Park

9.2/10 (331 reviews)

Explore the great outdoors at Natchez National Historical Park, a lovely green space in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Auburn Museum & Historic Home

9.8/10 (9 reviews)

You can browse the exhibits at Auburn Museum & Historic Home, a museum with a story of its own, during your trip to Natchez. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

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Martin Performing Arts Center

Enjoy an outing to Martin Performing Arts Center during your stay in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

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Frequently asked questions

What's the area like around Mary Bird Perkins Cancer Center?

Mary Bird Perkins Cancer Center is located in Natchez. This historic area is known for its beautiful river views and array of dining options. You'll find 139 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Mary Bird Perkins Cancer Center?

Adjacent to Mary Bird Perkins Cancer Center, Excellent Inn & Suites is one of the top choices for your stay based on our traveler data. Another good choice is Days Inn by Wyndham Natchez, located just 0.4 mi (0.7 km) away.

How many hotels are there close to Mary Bird Perkins Cancer Center?

Expedia has 139 hotels and other accommodations a few miles from Mary Bird Perkins Cancer Center.

If I need to cancel the hotel reservation for my stay near Mary Bird Perkins Cancer Center, will I receive a refund?

Yes, most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best deals available near Mary Bird Perkins Cancer Center.

Where can I learn more about changing or cancelling my trip in the area near Mary Bird Perkins Cancer Center?

For additional details about changing or cancelling your stay near Mary Bird Perkins Cancer Center, go to https://www.expedia.com/service/.

What can I see and do near Mary Bird Perkins Cancer Center?

Rosalie Mansion, Rhythm Night Club Museum, and Auburn Museum & Historic Home feature a variety of fascinating exhibits to see while you're in town. Longwood, Natchez National Historical Park, and Magnolia Hall are monuments to see when you're exploring the area around Mary Bird Perkins Cancer Center. For cultural attractions near Mary Bird Perkins Cancer Center, head to Natchez City Auditorium, Stratton Chapel Gallery, and William Johnson House Museum.

Find hotels near Mary Bird Perkins Cancer Center, Natchez from ₩105,459

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Our top choices for Mary Bird Perkins Cancer Center hotels

1. Monmouth Historic Inns and Gardens

2. Dunleith Historic Inn

3. Excellent Inn & Suites

4. Days Inn by Wyndham Natchez

5. Choctaw Hall Bed and Breakfast

6. Stone House Musical B&B

7. Brandon Hall Plantation

8. Riverboat Bed & Breakfast

9. Natchez Manor Bed & Breakfast

10. The Beaumont House

11. Devereaux Shields House

12. The Guest House Historic Mansion

13. The King's Daughters Bed and Breakfast

14. Natchez Grand Hotel & Suites on the River

15. Weymouth Hall B&B

16. Hampton Inn & Suites Natchez

17. The Bridges Hotel

18. The Burn Bed and Breakfast

19. TownePlace Suites by Marriott Vidalia Riverfront

20. Clarion Suites Vidalia Riverfront

Compare popular hotels close to Mary Bird Perkins Cancer Center

Top Mary Bird Perkins Cancer Center Hotel Reviews

Natchez Grand Hotel & Suites On the River

The Guest House Historic Mansion

Excellent Inn & Suites

Holiday Inn Express Hotel & Suites Natchez South by IHG

Monmouth Historic Inns and Gardens

The Hotel Vue

Linden Historic Bed & Breakfast

Other attractions near Mary Bird Perkins Cancer Center

Longwood

Grand Village of the Natchez Indians

Elms Court

Alcorn State University

Melrose

Natchez National Historical Park

Auburn Museum & Historic Home

Martin Performing Arts Center

Frequently asked questions