The Best Hotels Closest to Mary Bird Perkins Cancer Center in Natchez for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Mary Bird Perkins Cancer Center hotels

A large, two-story building with a symmetrical facade, surrounded by trees and illuminated by string lights.

A formal dining room with a long table set for a meal, surrounded by upholstered chairs.

A grand room with a chandelier, a piano, a sofa, and a table with a vase of flowers.

A bar area with a bartender pouring a drink into a glass, a shelf with various liquor bottles, and two glasses with a red drink on the counter.

1. Monmouth Historic Inns and Gardens

3.1 km from Mary Bird Perkins Cancer Center

Diana

₩193,104

₩245,259 total

includes taxes & fees

Oct 31 - Nov 1

A large, symmetrical building with a central entrance flanked by columns, surrounded by a well-maintained lawn.

A restaurant with brick walls, wooden beams, and plaid chairs. Tables are set with white tablecloths and silverware.

A room with a fireplace, ornate chairs, a round table, and a large mirror.

A porch with white rocking chairs and a black wrought iron railing.

2. Dunleith Historic Inn

2.9 km from Mary Bird Perkins Cancer Center

Herbert

₩190,111

₩256,058 total

includes taxes & fees

Nov 1 - Nov 2

A reception area with a wooden reception desk, a black circular wall art, and a modern ceiling design.

A bathroom with a large mirror, a sink, and a trash bin.

A modern kitchen with blue cabinets, a central island, and a seating area with round tables and chairs.

A motel with a blue and white exterior, a gas station, and a parking lot.

3. Excellent Inn & Suites

0.2 km from Mary Bird Perkins Cancer Center

Mary

₩126,725

₩142,093 total

includes taxes & fees

Nov 8 - Nov 9

A building with a central entrance, columns, and a balcony with railings.

A covered outdoor seating area with a table and benches, surrounded by trees and a building with a porch.

A hotel room with two beds, a bench, a nightstand, and a lamp.

4. Days Inn by Wyndham Natchez

0.7 km from Mary Bird Perkins Cancer Center

Glynn

₩93,596

₩105,641 total

includes taxes & fees

Oct 21 - Oct 22

A two-story house with a covered porch, brick exterior, and white columns.

A traditional living room with a fireplace, a bookshelf, and a chandelier.

A dining room with a round table set for six, surrounded by wooden chairs.

A spacious living room with a wooden coffee table, a sofa, and a dining table. There are potted plants and a chandelier.

5. Concord Quarters

4.4 km from Mary Bird Perkins Cancer Center

Justin

₩135,173

₩151,372 total

includes taxes & fees

Nov 16 - Nov 17

A balcony with a sofa, a small table, and a stool. There is a view of buildings and a sunset in the background.

A cozy outdoor seating area with a sofa, coffee table, and chairs.

A view through a window with a street scene, including buildings and a street lamp.

A living room with a coffee table, two armchairs, a painting on the wall, a kitchen area with white cabinets, and a wooden table.

6. Natchez Manor Bed & Breakfast

4 km from Mary Bird Perkins Cancer Center

Jill S.

₩185,380

₩206,600 total

includes taxes & fees

Nov 9 - Nov 10

A two-story building with a prominent entrance and large windows.

A hotel room with two beds, a sitting area with a chair and table, a bathroom visible through an open door, and a large mirror.

A dining area with tables and chairs, large windows with curtains, and a patterned carpet.

A balcony with a green cushion and a metal chair, overlooking a cityscape with buildings and a cloudy sky.

7. The Guest House Historic Mansion

4.2 km from Mary Bird Perkins Cancer Center

Jodie

₩149,897

₩167,568 total

includes taxes & fees

Nov 2 - Nov 3

A large, two-story house with a prominent tree in front, white exterior, and a covered porch.

A living room with a sofa, a glass coffee table, a patterned rug, a wooden chair, and a kitchen in the background.

A four-poster bed with a canopy, a dresser, a chair, and a decorative vase.

A dining table with a chessboard, a potted plant, and leather chairs in a room with a bookshelf and a lamp in the background.

8. Brandon Hall Plantation

16.2 km from Mary Bird Perkins Cancer Center

Elizabeth

₩347,922

₩372,275 total

includes taxes & fees

Oct 20 - Oct 21

A brown leather armchair with a cushion that has text, positioned in front of a window with white curtains.

A dining area with a table set for four, surrounded by white chairs, large windows with a view of greenery, and a chandelier.

A corridor with a closed door labeled "Carriage House," a wicker chair, and a hanging lantern.

A dining area with a dark table, white chairs, a chandelier, and a window with curtains.

9. The Natchez Pearl

4.3 km from Mary Bird Perkins Cancer Center

John

₩167,558

₩327,137 total

includes taxes & fees

Oct 25 - Oct 26

A two-story house with a front porch, a brick pathway, and a large tree.

A spacious living room with hardwood floors, a chandelier, a fireplace, and a dining area in the background.

A room with a wooden dresser, a large ornate mirror, a vase with flowers, a framed painting, and a chair.

A spacious living room with a large, ornate chandelier, a patterned area rug, and classic furniture including a sofa and armchairs.

10. The Beaumont House

3.7 km from Mary Bird Perkins Cancer Center

Sherrill

₩226,629

₩251,975 total

includes taxes & fees

Nov 9 - Nov 10

A two-story house with a porch, a white picket fence, and an American flag.

A traditional living room with a sofa, armchairs, a coffee table, a fireplace, and decorative items.

A porch with a bench and two rocking chairs, a white railing, and a view of a brick wall and trees.

A dining room with a chandelier, a fireplace, and a painting on the wall.

11. Riverboat Bed & Breakfast

4.3 km from Mary Bird Perkins Cancer Center

Christopher

₩286,183

₩317,483 total

includes taxes & fees

Nov 15 - Nov 16

A brick building with a green awning labeled "GRAND HOTEL".

A cozy living room with a sofa, armchairs, a coffee table, and a dining area with chairs and a table. Large windows with curtains provide natural light and views.

A spacious living room with a fireplace, a staircase, and a dining area.

A sign for the Grand Hotel Natchitoches with a brick archway and a garden with colorful flowers.

12. Natchez Grand Hotel & Suites on the River

4.5 km from Mary Bird Perkins Cancer Center

Joyce

₩168,255

₩220,125 total

includes taxes & fees

Nov 1 - Nov 2

A deck with two chairs and a table, overlooking a river and a sunset.

A bathroom with a white shower curtain, a white sink with a large bowl, a toilet, and a mirror with a wooden frame.

A dining room with a fireplace, ornate mirror, chandelier, and a large window with a view.

A pool area with statues, a white fence, and a sunset view.

13. Weymouth Hall B&B

5.6 km from Mary Bird Perkins Cancer Center

Harley

₩167,277

₩186,687 total

includes taxes & fees

Nov 10 - Nov 11

A modern restaurant with a long counter, multiple seating areas, and a distinctive blue brick wall.

A modern hotel room with a large bed, two bedside tables, a nightstand, a desk, and a chair.

A modern hotel lobby with a seating area, a desk, and a decorative light fixture.

A modern living room with a fireplace, two armchairs, a coffee table, and a large window with curtains.

14. The Bridges Hotel

4.1 km from Mary Bird Perkins Cancer Center

Thomas

₩124,565

₩139,704 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a large bed, two bedside lamps, a flat-screen TV, a dresser, and a patterned carpet.

A white building with a sign reading 'Hampton Inn & Suites.'

A conference room with a long table, chairs, a kitchenette, and a bar area.

A conference room with tables and chairs, a whiteboard, a TV, and a window with blinds.

15. Hampton Inn & Suites Natchez

3.9 km from Mary Bird Perkins Cancer Center

Bobbi

₩217,725

₩242,179 total

includes taxes & fees

Oct 31 - Nov 1

A spacious living area with a modern sofa set, a black and white rug, and large windows offering a view of the outdoors.

A swimming pool with lounge chairs and a building with multiple floors and large windows.

A modern living room with a sectional sofa, a flat-screen TV mounted on a red wall, and a large window offering a view of the outdoors.

A modern hotel room with a large bed, a flat-screen TV, a dining area with a table and chairs, and a view of the outdoors.

16. Magnolia Hotel, BW Signature Collection

4.1 km from Mary Bird Perkins Cancer Center

Carol

₩181,223

₩202,028 total

includes taxes & fees

Oct 26 - Oct 27

A patio with a fire pit, outdoor seating, and a view of a park.

A modern kitchenette with a microwave, oven, and sink. There is a sofa with cushions and a chair in the living area.

A townhouse hotel with a modern design, featuring a covered entrance and a well-maintained garden area.

A modern kitchen with dark wood cabinets, a herringbone floor pattern, and a central island with a red bowl of fruit.

17. TownePlace Suites by Marriott Vidalia Riverfront

5.4 km from Mary Bird Perkins Cancer Center

Lorenza

₩227,109

₩281,046 total

includes taxes & fees

Nov 2 - Nov 3

A hotel lobby with a fireplace, seating area, and a reception desk.

A hotel room with a kitchenette, a bed, a sofa, a desk, and a bathroom.

A modern kitchen with wooden cabinets, a white countertop, and a coffee machine.

A Holiday Inn Express & Suites with a large parking lot, a building entrance, and a signboard.

18. Holiday Inn Express Hotel & Suites Natchez South by IHG

3.8 km from Mary Bird Perkins Cancer Center

thomas

₩187,971

₩209,453 total

includes taxes & fees

Oct 27 - Oct 28

A terrace with lounge chairs and umbrellas overlooking a river.

A room with a large window, a patterned rug, and a wooden chair.

A spacious living room with a leather sofa, two patterned armchairs, a wooden coffee table, and a decorative plant arrangement. Large windows with curtains provide natural light and a view.

A hotel room with two beds, a desk, a television, and a view of the outdoors.

19. Clarion Suites Vidalia Riverfront

5.4 km from Mary Bird Perkins Cancer Center

Dwight

₩150,863

₩174,623 total

includes taxes & fees

Oct 26 - Oct 27

A Red Carpet Inn with a sign indicating free hot breakfast, a Cash Saver nearby, and a parking area.

A reception area with a wooden reception desk, framed pictures on the wall, a chandelier, and a view of the outside through large windows.

A small office with a desk, chair, laptop, potted plant, framed picture, and a shelf with magazines.

A hotel room with two beds, each with green bedding, a wooden headboard, a nightstand with a lamp, and a window with curtains.

20. Red Carpet Inn

4.3 km from Mary Bird Perkins Cancer Center

alison

₩108,621

₩122,165 total

includes taxes & fees

Nov 9 - Nov 10

View all properties

Compare popular hotels close to Mary Bird Perkins Cancer Center

Property	Property class	Guest rating
Monmouth Historic Inns and Gardens	9.4 Exceptional 727 reviews	View
Dunleith Historic Inn	8.8 Excellent 560 reviews	View
Excellent Inn & Suites	8.0 Very good 327 reviews	View
Days Inn by Wyndham Natchez	6.6 1,000 reviews	View
Concord Quarters	10.0 Exceptional 118 reviews	View

Top Mary Bird Perkins Cancer Center Hotel Reviews

The Guest House Historic Mansion

10/10 Excellent

"The room was clean and comfortable. The bed was very nice and cozy. The property itself needs some sprucing up but was well kept and clean. If the owners had more capital to help in maintenance and upgrades this would help immensely. Staff should have some uniforms with insignia and nametags."

Excellent Inn & Suites

8/10 Good

"Clean room"

Natchez Grand Hotel

10/10 Excellent

"Good stay. Got a room upgrade"

The Hotel Vue

8/10 Good

"There need to be a microwave in the rooms. I wasn’t able to heat up my food. Other than that everything was good."

Clarion Suites Vidalia Riverfront

8/10 Good

"i’m"

Red Carpet Inn

10/10 Excellent

"Best value I’ve found in Natchez. Been here many times and will return. The best value for lodging you’ll find in 2026 and beyond, clean and comfortable in a safe and welcoming environment."

Days Inn by Wyndham Natchez

8/10 Good

"Staff was friendly and helpful. The bed was comfy, no bugs. My only complaint is the room smelled a little like mildew."

Monmouth Historic Inns and Gardens

10/10 Excellent

"The staff was wonderful. Excellent breakfast."

Hampton Inn & Suites Natchez

10/10 Excellent

"Hampton Inn is yet to let me down . Friendly staff, good breakfast , good location , good house keeping. It’s just good ."

Other attractions near Mary Bird Perkins Cancer Center

Longwood

9.4/10 (312 reviews)

You can find out about the history of Natchez with a stop at Longwood. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

See properties

Grand Village of the Natchez Indians

You can spend time browsing the exhibits at Grand Village of the Natchez Indians during your travels in Natchez. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

See properties

Elms Court

10.0/10 (5 reviews)

You can find out about the history of Natchez with a stop at Elms Court. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

See properties

Alcorn State University

Walk around the campus at Alcorn State University during your stay in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

See properties

Melrose

9.0/10 (133 reviews)

Find out about the history of Natchez when you take a trip to Melrose. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

See properties

Natchez National Historical Park

9.2/10 (331 reviews)

Explore the great outdoors at Natchez National Historical Park, a lovely green space in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

See properties

Auburn Museum & Historic Home

9.8/10 (9 reviews)

You can browse the exhibits at Auburn Museum & Historic Home, a museum with a story of its own, during your trip to Natchez. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.

See properties

Martin Performing Arts Center

Enjoy an outing to Martin Performing Arts Center during your stay in Natchez. Stroll along the area's riverfront, or simply savor its top-notch restaurants.

See properties

Frequently asked questions

What's the area like around Mary Bird Perkins Cancer Center?

Mary Bird Perkins Cancer Center is located in Natchez. This historic area is known for its beautiful river views and array of dining options. You'll find 139 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Mary Bird Perkins Cancer Center?

Adjacent to Mary Bird Perkins Cancer Center, Excellent Inn & Suites is one of the top choices for your stay based on our traveler data. Another good choice is Days Inn by Wyndham Natchez, located just 0.4 mi (0.7 km) away.

How many hotels are there close to Mary Bird Perkins Cancer Center?

Expedia has 139 hotels and other accommodations a few miles from Mary Bird Perkins Cancer Center.

If I need to cancel the hotel reservation for my stay near Mary Bird Perkins Cancer Center, will I receive a refund?

Yes, most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best deals available near Mary Bird Perkins Cancer Center.

Where can I learn more about changing or cancelling my trip in the area near Mary Bird Perkins Cancer Center?

For additional details about changing or cancelling your stay near Mary Bird Perkins Cancer Center, go to https://www.expedia.com/service/.

What can I see and do near Mary Bird Perkins Cancer Center?

Rosalie Mansion, Rhythm Night Club Museum, and Auburn Museum & Historic Home feature a variety of fascinating exhibits to see while you're in town. Longwood, Natchez National Historical Park, and Magnolia Hall are monuments to see when you're exploring the area around Mary Bird Perkins Cancer Center. For cultural attractions near Mary Bird Perkins Cancer Center, head to Natchez City Auditorium, Stratton Chapel Gallery, and William Johnson House Museum.

Find hotels near Mary Bird Perkins Cancer Center, Natchez from ₩105,641

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mary Bird Perkins Cancer Center hotels

1. Monmouth Historic Inns and Gardens

2. Dunleith Historic Inn

3. Excellent Inn & Suites

4. Days Inn by Wyndham Natchez

5. Concord Quarters

6. Natchez Manor Bed & Breakfast

7. The Guest House Historic Mansion

8. Brandon Hall Plantation

9. The Natchez Pearl

10. The Beaumont House

11. Riverboat Bed & Breakfast

12. Natchez Grand Hotel & Suites on the River

13. Weymouth Hall B&B

14. The Bridges Hotel

15. Hampton Inn & Suites Natchez

16. Magnolia Hotel, BW Signature Collection

17. TownePlace Suites by Marriott Vidalia Riverfront

18. Holiday Inn Express Hotel & Suites Natchez South by IHG

19. Clarion Suites Vidalia Riverfront

20. Red Carpet Inn

Compare popular hotels close to Mary Bird Perkins Cancer Center

Top Mary Bird Perkins Cancer Center Hotel Reviews

The Guest House Historic Mansion

Excellent Inn & Suites

Natchez Grand Hotel

The Hotel Vue

Clarion Suites Vidalia Riverfront

Red Carpet Inn

Days Inn by Wyndham Natchez

Monmouth Historic Inns and Gardens

Hampton Inn & Suites Natchez

Other attractions near Mary Bird Perkins Cancer Center

Longwood

Grand Village of the Natchez Indians

Elms Court

Alcorn State University

Melrose

Natchez National Historical Park

Auburn Museum & Historic Home

Martin Performing Arts Center

Frequently asked questions