Find hotels in Matlacha Isles, Cape Coral from ₩80,668

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 21 - Nov 22
Tomorrow
Nov 22 - Nov 23
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Discover 14,152 Matlacha Isles hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4.0 star property
17.2 km from Matlacha Isles
8.4 out of 10, Very Good, (1008)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is ₩293,103
₩363,632 total
includes taxes & fees
Nov 30 - Dec 1
Marriott Sanibel Harbour Resort & Spa
Interior entrance
Allure Suites

Allure Suites

3.0 star property
17 km from Matlacha Isles
7.6 out of 10, Good, (1006)
"Was clean staff was very nice"
United States
Richard J
Allure Suites
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
18.1 km from Matlacha Isles
8.6 out of 10, Excellent, (1003)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
The price is ₩139,387
₩155,417 total
includes taxes & fees
Dec 1 - Dec 2
Residence Inn by Marriott Fort Myers Sanibel
Property amenity
Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75

2.5 star property
24.8 km from Matlacha Isles
9.6 out of 10, Exceptional, (331)
"Friendly staff, great breakfast, clean room. "
United States
Shellie
The price is ₩136,687
₩152,406 total
includes taxes & fees
Nov 30 - Dec 1
Comfort Suites Fort Myers East I-75
Lobby
Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites

2.5 star property
20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1079)
"Service was great, cleanliness was good ad well, really enjoyed breakfast"
United States
Tina
The price is ₩106,976
₩119,278 total
includes taxes & fees
Nov 26 - Nov 27
Best Western Fort Myers Inn & Suites
Lobby
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2.0 star property
28 km from Matlacha Isles
8.0 out of 10, Very Good, (1485)
"Clean, comfortable and quiet facility… I would stay here again!"
United States
John
The price is ₩96,030
₩107,078 total
includes taxes & fees
Nov 26 - Nov 27
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Laptop workspace, blackout drapes, free WiFi, bed sheets
StudioRes Fort Myers Airport

StudioRes Fort Myers Airport

3.0 star property
29.5 km from Matlacha Isles
8.4 out of 10, Very Good, (8)
"Clean room, staff, amenities, easy check in, easy access to gas stations, restaurants, and retail. "
United States
Gina
The price is ₩131,024
₩146,092 total
includes taxes & fees
Nov 30 - Dec 1
StudioRes Fort Myers Airport
Hypo-allergenic bedding, down comforters, individually decorated
Econo Lodge Fort Myers North

Econo Lodge Fort Myers North

2.0 star property
Hancock, 16.5 km from Matlacha Isles
5.6 out of 10, (296)
"Friendly staff great location close to beaches for a reasonable price"
United States
John
The price is ₩84,512
₩94,231 total
includes taxes & fees
Nov 23 - Nov 24
Econo Lodge Fort Myers North
Outdoor pool
Days Inn by Wyndham Fort Myers Springs Resort

Days Inn by Wyndham Fort Myers Springs Resort

2.5 star property
28 km from Matlacha Isles
6.0 out of 10, (1000)
"It was a really clean hotel "
United States
Tina
The price is ₩92,289
₩102,902 total
includes taxes & fees
Nov 26 - Nov 27
Days Inn by Wyndham Fort Myers Springs Resort
Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
20.4 km from Matlacha Isles
8.8 out of 10, Excellent, (1003)
"Great Place to Stay!"
United States
JUDY
The price is ₩174,644
₩194,730 total
includes taxes & fees
Nov 24 - Nov 25
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior
Best Western Fort Myers Waterfront

Best Western Fort Myers Waterfront

3.0 star property
Hancock, 16.7 km from Matlacha Isles
7.4 out of 10, Good, (1005)
"Great hospitality. Perfect view on the water. Great restaurant on site and IHOP next door. "
United States
Carol
The price is ₩148,410
₩165,478 total
includes taxes & fees
Nov 24 - Nov 25
Best Western Fort Myers Waterfront
Garden
Travelodge by Wyndham Fort Myers North

Travelodge by Wyndham Fort Myers North

2.0 star property
Hancock, 16.4 km from Matlacha Isles
5.8 out of 10, (1001)
"Great place to stay "
United States
Blaine
The price is ₩71,361
₩79,565 total
includes taxes & fees
Nov 23 - Nov 24
Travelodge by Wyndham Fort Myers North
Outdoor pool
Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd

2.5 star property
21 km from Matlacha Isles
9.4 out of 10, Exceptional, (1001)
"Clean room, friendly staff, nice breakfast"
United States
Mercedes
The price is ₩165,327
₩184,339 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn & Suites Fort Myers - Colonial Blvd
View from room
Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral

3.0 star property
20.4 km from Matlacha Isles
8.2 out of 10, Very Good, (1003)
"Was a terrific stay and they went out of their way to accommodate my injured dog even giving us a late checkout "
United States
laura
The price is ₩116,205
₩129,568 total
includes taxes & fees
Dec 22 - Dec 23
Courtyard by Marriott Fort Myers Cape Coral
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3.0 star property
18.3 km from Matlacha Isles
8.0 out of 10, Very Good, (1004)
"Great place to stay and breakfast was delicious "
United States
Keishly
The price is ₩136,462
₩152,155 total
includes taxes & fees
Nov 24 - Nov 25
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Interior entrance
Candlewood Suites Ft Myers I-75 by IHG

Candlewood Suites Ft Myers I-75 by IHG

2.5 star property
25.1 km from Matlacha Isles
8.0 out of 10, Very Good, (741)
"The suite is equipped with everything you need."
United States
Elizabet
The price is ₩101,334
₩112,987 total
includes taxes & fees
Nov 30 - Dec 1
Candlewood Suites Ft Myers I-75 by IHG
Pool
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

3.5 star property
17.9 km from Matlacha Isles
8.6 out of 10, Excellent, (832)
"Staff was friendly. "
United States
Jennifer
The price is ₩215,360
₩240,126 total
includes taxes & fees
Dec 4 - Dec 5
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
Exterior
Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

3.0 star property
24.7 km from Matlacha Isles
8.2 out of 10, Very Good, (1008)
"Goodlocation"
United States
Mary Michael
The price is ₩136,462
₩152,154 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Place Fort Myers/at The Forum
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 star property
19.9 km from Matlacha Isles
9.4 out of 10, Exceptional, (1010)
"Excellent room and price! Breakfast was great. Holiday Inn Express is doing everything right for a comfortable stay."
United States
Denise
The price is ₩116,652
₩130,066 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Property amenity
MainStay Suites Fort Myers East I-75

MainStay Suites Fort Myers East I-75

2.5 star property
24.7 km from Matlacha Isles
9.6 out of 10, Exceptional, (202)
"Overall good hotel for a reasonable price "
United States
Carolyn
The price is ₩137,186
₩152,963 total
includes taxes & fees
Nov 29 - Nov 30
MainStay Suites Fort Myers East I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most.

Pelican

If you're spending some time in Pelican, Tarpon Point and Harbour View Gallery are top sights worth seeing.

Cape Coral which includes a river or creek and a park

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Mariner

While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

North Fort Myers showing a sandy beach, general coastal views and a coastal town

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

Yacht Club

While there might not be top attractions in Yacht Club, you can explore the larger area and discover places like Cape Coral Yacht Club Beach and Dolphin Marina.

Top Matlacha Isles Hotel Reviews

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

10/10 Excellent
"The staff have been extremely kind, upbeat and positive! Our room, the lobby, and the pool area are immaculate! The environment is fun and relaxing at the same time! I love everything about Pink Shell!"
Belinda 1-night trip
Posted 6 hours ago
Pink Shell Beach Resort and Marina

Explore a world of travel with Expedia

Frequently asked questions

What is Matlacha Isles like?
Travelers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighborhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to kick up your feet after a day of exploring the sights in Cape Coral, you can choose from 16 Expedia hotels and other accommodations in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available in Matlacha Isles.
Where can I learn more about changing or cancelling my trip to Matlacha Isles?
To find more details about changing or cancelling your trip to Matlacha Isles, go to https://www.expedia.com/service/.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens, and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, be sure to visit other sights like Little Dead Key or Big Dead Key.