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Our top choices for Matlacha Isles hotels

3 restaurants, breakfast, lunch, dinner served; Italian cuisine
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,095 reviews)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
The price is ₩274,721
₩338,728 total
includes taxes & fees
Jan 11 - Jan 12
Lani Kai Beachfront Resort
Lobby
Baymont by Wyndham Punta Gorda/Port Charlotte

Baymont by Wyndham Punta Gorda/Port Charlotte

Baymont by Wyndham Punta Gorda/Port Charlotte
2.5 star property
28.9 km from Matlacha Isles
8.4 out of 10, Very Good, (1,159 reviews)
"Friendly staff, good breakfast. "
United States
Tom
The price is ₩129,511
₩145,052 total
includes taxes & fees
Jan 11 - Jan 12
Baymont by Wyndham Punta Gorda/Port Charlotte
Lobby
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
28 km from Matlacha Isles
8.0 out of 10, Very Good, (1,520 reviews)
"Loved the stay "
United States
Moosa Nazar
The price is ₩121,662
₩135,654 total
includes taxes & fees
Jan 11 - Jan 12
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Property entrance
Holiday Inn Express & Suites Punta Gorda by IHG

Holiday Inn Express & Suites Punta Gorda by IHG

Holiday Inn Express & Suites Punta Gorda by IHG
2.5 star property
28.8 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean room, good location, reasonable price."
United States
John
The price is ₩177,333
₩198,613 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Express & Suites Punta Gorda by IHG
Exterior
Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
18.2 km from Matlacha Isles
7.2 out of 10, Good, (156 reviews)
"The service at the front desk was exceptional, the new manager is doing an amazing job!!"
United States
Sandro
The price is ₩129,366
₩144,243 total
includes taxes & fees
Jan 11 - Jan 12
Woodspring Suites Fort Myers - Cape Coral
Laptop workspace, blackout drapes, free WiFi, bed sheets
StudioRes Fort Myers Airport

StudioRes Fort Myers Airport

StudioRes Fort Myers Airport
3.0 star property
29.5 km from Matlacha Isles
9.2 out of 10, Wonderful, (24 reviews)
"Loved stay here!!! "
United States
Melissa
The price is ₩159,382
₩177,711 total
includes taxes & fees
Jan 18 - Jan 19
StudioRes Fort Myers Airport
Indoor pool
Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
27.9 km from Matlacha Isles
8.8 out of 10, Excellent, (1,112 reviews)
"Comfortable rooms and beds, good breakfast and easy access to baseball parks."
United States
Javier
The price is ₩150,515
₩167,824 total
includes taxes & fees
Jan 11 - Jan 12
Comfort Inn & Suites Fort Myers Airport
Floating Coconut Cottage Houseboat | Terrace/patio
Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
20.3 km from Matlacha Isles
8.6 out of 10, Excellent, (914 reviews)
"Staff was very helpful at check-in; room was clean. As a solo female traveler, I felt safe. "
United States
Kimberly
Latitude 26 Waterfront Resort & Marina
Sundeck
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
20.4 km from Matlacha Isles
8.8 out of 10, Excellent, (1,002 reviews)
"Great Place to Stay!"
United States
JUDY
The price is ₩228,934
₩255,272 total
includes taxes & fees
Jan 18 - Jan 19
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior
Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1,128 reviews)
"Clean room, old property and fresh, varied options for breakfast"
Canada
supriya
The price is ₩129,526
₩144,422 total
includes taxes & fees
Jan 11 - Jan 12
Best Western Fort Myers Inn & Suites
Property grounds
Boca Grande Hotel

Boca Grande Hotel

Boca Grande Hotel
2.5 star property
28.8 km from Matlacha Isles
8.8 out of 10, Excellent, (587 reviews)
"This place was awesome!"
United States
Dharyl
The price is ₩181,694
₩203,497 total
includes taxes & fees
Jan 11 - Jan 12
Boca Grande Hotel
On the beach, sun loungers, beach towels
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,520 reviews)
"Great location. "
United States
Patricia
The price is ₩376,469
₩456,103 total
includes taxes & fees
Jan 11 - Jan 12
Sanibel Island Beach Resort
Exterior
Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum
3.0 star property
24.7 km from Matlacha Isles
8.2 out of 10, Very Good, (1,003 reviews)
"Friendly staff, good breakfast good location."
United States
Lily
The price is ₩165,705
₩184,760 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt Place Fort Myers/at The Forum
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
19.9 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,000 reviews)
"Spotless rooms , great breakfast , courteous staff ! Had a great time !"
United States
Arijit
The price is ₩213,030
₩237,528 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Lobby
Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
24.8 km from Matlacha Isles
9.6 out of 10, Exceptional, (372 reviews)
"Friendly staff, great breakfast, clean room. "
United States
Shellie
The price is ₩158,437
₩176,657 total
includes taxes & fees
Jan 11 - Jan 12
Comfort Suites Fort Myers East I-75
Reception
Knights Inn Punta Gorda

Knights Inn Punta Gorda

Knights Inn Punta Gorda
1.5 star property
28.5 km from Matlacha Isles
7.2 out of 10, Good, (955 reviews)
"Very clean and well organized. Staff was professional and well organized, as well."
United States
Sandra
The price is ₩123,552
₩138,378 total
includes taxes & fees
Jan 11 - Jan 12
Knights Inn Punta Gorda
2 outdoor pools
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
22.8 km from Matlacha Isles
8.6 out of 10, Excellent, (1,586 reviews)
"Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach"
United States
Erika
The Lighthouse Resort Inn & Suites
1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down comforters, desk, laptop workspace
Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
18.4 km from Matlacha Isles
7.6 out of 10, Good, (211 reviews)
"Clean room and staff was excellent "
Canada
SURINDER
The price is ₩122,748
₩158,688 total
includes taxes & fees
Jan 11 - Jan 12
Quality Inn Fort Myers Cape Coral
Reception
Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
19.3 km from Matlacha Isles
7.6 out of 10, Good, (1,142 reviews)
"Loved it. The staff was great rooms were clean. "
United States
Austin
The price is ₩110,688
₩123,417 total
includes taxes & fees
Jan 11 - Jan 12
Americas Best Value Inn Ft. Myers
Lobby
Quality Suites Fort Myers I-75

Quality Suites Fort Myers I-75

Quality Suites Fort Myers I-75
2.5 star property
27.1 km from Matlacha Isles
8.2 out of 10, Very Good, (1,001 reviews)
"Staff was courteous, breakfast was ok, very low water pressure in the shower, room was overall ok."
United States
JUNIOR
The price is ₩143,901
₩160,457 total
includes taxes & fees
Jan 11 - Jan 12
Quality Suites Fort Myers I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most.

Pelican

If you're spending some time in Pelican, Tarpon Point and Harbour View Gallery are top sights worth seeing.

Cape Coral which includes a river or creek and a park

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club

While there might not be top attractions in Yacht Club, you can explore the larger area and discover places like Cape Coral Yacht Club Beach and Dolphin Marina.

North Fort Myers showing a sandy beach, general coastal views and a coastal town

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

Mariner

While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

Top Matlacha Isles Hotel Reviews

Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

10/10 Excellent
"Good"
Griselle 1-night trip
Posted 2 days ago
Hyatt Place Fort Myers/at The Forum

Frequently asked questions

What is Matlacha Isles like?
Travelers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighborhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to kick up your feet after a day of exploring the sights in Cape Coral, you can choose from 17 Expedia hotels and other accommodations in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available in Matlacha Isles.
Where can I learn more about changing or cancelling my trip to Matlacha Isles?
To find more details about changing or cancelling your trip to Matlacha Isles, go to https://www.expedia.com/service/.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens, and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, be sure to visit other sights like Little Dead Key or Big Dead Key.