Matlacha Isles Vacations

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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
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Pelican

1 out of top 10 points of interest in this area

If you're spending some time in Pelican, Tarpon Point and Harbour View Gallery are top sights worth seeing.

Find hotels in Pelican

Matlacha Isles Hotel Deals

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street, Fort Myers Beach, FL
The price is ₩222,165 per night from Aug 24 to Aug 25
₩222,165
₩301,539 total
Aug 24 - Aug 25
includes taxes & fees
8.8/10 Excellent! (1,366 reviews)
"Excellent"

Reviewed on Aug 13, 2025

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
The price is ₩276,465 per night from Aug 21 to Aug 22
₩276,465
₩369,765 total
Aug 21 - Aug 22
includes taxes & fees
8.6/10 Excellent! (1,011 reviews)
"Property was great, several dining options. The only suggestion I have is that you leave a broom and dustpan in rooms so guests can sweep up sand and not have to have housekeeping do it."

Reviewed on Aug 12, 2025

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
Fully refundableReserve now, pay when you stay
The price is ₩315,802 per night from Aug 17 to Aug 18
₩315,802
₩386,595 total
Aug 17 - Aug 18
includes taxes & fees
9/10 Wonderful! (1,272 reviews)
"Delightful! Clean room, helpful and friendly staff and great location. Beautiful beach with great shelling, and the pool & pool bar was very relaxing."

Reviewed on Aug 11, 2025

Sanibel Island Beach Resort
See all 13,416 properties in Matlacha Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles vacation package cost?
Our Matlacha Isles vacation packages, which begin from just , are the best way to save loads of cash. Select your favorite flights, hotels and rental cars to create a custom-built itinerary.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotel and flight bookings, add on extras such as activities, and save with a Matlacha Isles vacation package. You won't just walk away with awesome discounts on your trip — you'll have loads of choice at your fingertips too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 hotels around the globe. Your next epic adventure begins right here, right now!
Where should I stay in Matlacha Isles?
If you're itching to be where the action is, stay near Sun Splash Water Park. Many happy campers book a hotel around this renowned tourist attraction.
What are the top hotels in Matlacha Isles?
Reserve a room at The Perfect Day In Matlacha Direct Gulf Access. It's one of the neighborhood's most popular hotels. Another highly rated option in Matlacha Isles is Fun'n Sun - Charming 3 Br/ 3 Baths Waterfront Villa W. Boat Lift.
How far in advance should I book my Matlacha Isles vacation?
Smart travelers will likely want to reserve their seats early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you've left things to the last minute, don't stress. Low prices occasionally become available just weeks prior to departure.
What does an Expedia Matlacha Isles travel package include?
Expedia has all you need to organize your Matlacha Isles trip, but how you structure your package depends on you. Select from a combination of rental cars, hotels and flights. Chasing some experiences or tours to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a deal to suit your needs.
What should I know before booking a Matlacha Isles travel package?
Bundling your bookings into a Matlacha Isles vacation package is the easiest way to organize your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Matlacha Isles Expedia vacation package?
Yes, definitely. Expedia has more than 550 partner airlines to select from globally. With all that choice, finding the ideal carrier to bring you to Matlacha Isles will be easy.
If I'm not able to travel, can I cancel my Matlacha Isles vacation package?
Don't worry if you're rethinking your Matlacha Isles vacation package — you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We get that your circumstances can suddenly change, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.