Midtown Vacations
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Where to stay in Midtown
Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Downtown St. Louis
3 out of top 10 points of interest in this area
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Downtown West
3 out of top 10 points of interest in this area
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Midtown Hotel Deals
Element by Marriott St. Louis Midtown
3763 Forest Park Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
₩191,187
₩223,553 total
Aug 30 - Aug 31
includes taxes & fees
9/10 Wonderful! (811 reviews)
"I was not prepared for the $50 parking. That was an unexpected expense since I already paid so much for the room and nothing was open since it was a Sunday."
Reviewed on Aug 17, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
₩189,842
₩223,879 total
Sep 4 - Sep 5
includes taxes & fees
8.6/10 Excellent! (4,196 reviews)
"Staff was very helpful and friendly."
Reviewed on Aug 18, 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
₩129,760
₩151,480 total
Aug 30 - Aug 31
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Midtown vacation package cost?
Starting from a low , a package is your gateway to low-priced travel. Build your own Midtown trip by selecting from our great range of hotels, flights and rental cars.
How do I get a cheap travel package to Midtown?
Bundle your bookings with Expedia to save big bucks on your next trip. With over 550 partner airlines and 1,000,000 properties throughout the world, your Midtown vacation package can be tailored exactly to suit your travel style. With all that extra cash, why not add one or two awesome tours and activities? It's an easy way to unlock even more savings. The vacation you've always dreamed of in Midtown is much closer than you thought!
Where should I stay in Midtown?
A trip to Midtown isn't complete until you've seen Busch Stadium and Gateway Arch. Book a hotel within walking distance so you can easily access these terrific tourist attractions.
What are the top hotels in Midtown?
Book a room at Element St. Louis Midtown. It's one of this neighborhood's most in-demand hotels. Another reputable option in Midtown is Residence Inn by Marriott St Louis Downtown.
How far in advance should I book my Midtown vacation?
While prices fluctuate, we generally advise booking your vacation as soon as possible. Most international fares are available on Expedia up to 12 months in advance. If you're booking late, you might still get lucky. Cheap journeys to Midtown occasionally appear only weeks before departure.
What does an Expedia Midtown travel package include?
With Expedia, you can select a combination of car rentals, hotels and flights to build your ideal Midtown package. Once you've made your booking, you can add on the fun things like tours and experiences. Remember — the more you bundle, the bigger the savings!
What should I know before booking a Midtown travel package?
You'll land big savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one spot makes trip planning easier. So why waste time or money? Whether you're putting together an upscale romantic escape or an affordable family break, browse our vacation packages today.
Can I choose my airline with a Midtown Expedia vacation package?
With a vacation package, you're the boss. Whether you're looking to fly to Midtown in economy or business class, simply select from the available airline options. Expedia has access to over 550 airline partners worldwide.
If I'm not able to travel, can I cancel my Midtown vacation package?
Don't stress if you're rethinking your Midtown vacation package — it's possible to cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We understand life can occasionally throw a spanner in the travel works, so head to our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.
Stay near popular Midtown attractions
St. Louis University
8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Photo by Wanderlustfemale
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's fascinating museums or attend a baseball game.
Chaifetz Arena
8.8/10 (59 reviews)
Catch an event at Chaifetz Arena during your trip to St. Louis. Amble around the area's picturesque gardens or attend a baseball game.
Harris-Stowe State University
Explore the campus of Harris-Stowe State University during your visit to St. Louis.
City Foundry STL
City Foundry STL is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?
Museum of Contemporary Religious Art
You can spend an afternoon exploring the galleries in Museum of Contemporary Religious Art during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a sporting event.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.