Ortigia Vacations

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Where to stay in Ortigia

Find the best Ortigia areas and neighborhoods for the activities you enjoy most. Learn more about Ortigia
The Sanctuary of the Madonna delle Lacrime was erected in memory of the miraculous lacrimation of the effigy depicting the Immaculate Heart of Mary, placed to the bedside of the spouses Lannuso at their humble home in Via degli Orti in Syracuse, in 1953.

Santa Lucia

1 out of top 10 points of interest in this area
4.5/5(27 area reviews)

Santa Lucia is noteworthy for its historic sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

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Ortigia Hotel Deals

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

4 out of 5
Via Vittorio Veneto 93 Syracuse SR
Fully refundableReserve now, pay when you stay
9.4/10 Exceptional! (914 reviews)
Nice room- great view.

Reviewed on Jan 15, 2026

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Algila' Ortigia Charme Hotel
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5 out of 5
Viale Mazzini, 12 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is ₩279,357 per night from Feb 10 to Feb 11
₩279,357
₩324,537 total
Feb 10 - Feb 11
includes taxes & fees
8.8/10 Excellent! (569 reviews)
Stunning hotel and area on the waterfront in Ortigia. Strongly recommend everything except the restaurant. Food was marginal for the price with much better options close by

Reviewed on Dec 31, 2025

Grand Hotel Ortigia Siracusa
Palazzo Artemide - VRetreats

Palazzo Artemide - VRetreats

4 out of 5
Via Roma 66 Syracuse SR
9.4/10 Exceptional! (657 reviews)
Very clean, elegant and comfortable. Pleasant and helpful staff.

Reviewed on Jan 11, 2026

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Palazzo Artemide - VRetreats
See all 798 properties in Ortigia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Ortigia vacation package cost?
Our Ortigia vacation packages, which start from as low as , are an awesome way to save big bucks. Handpick your preferred hotels, flights and more to create your ideal escape.
How do I get a cheap travel package to Ortigia?
Imagine all the fabulous things you could do in Ortigia with a wad of extra cash in your pocket. Watch your savings stack up when you bundle your flights, hotels and other bookings into an Ortigia vacation package. You have plenty of choice when you book with Expedia too. In fact, you can choose from more than 550 airlines and 1,000,000 hotels around the world. Whether you're taking a vacation with the family or surprising your special someone, planning a trip to Ortigia is better with a package.
Where should I stay in Ortigia?
Most travelers who visit Ortigia include both Cathedral of Syracuse and Temple of Apollo on their to-do lists. Why not select a hotel that's close to these fantastic attractions?
What are the top hotels in Ortigia?
Get your escape off to a flying start by booking a room at Le Dimore Del Mito - Gaia. It's one of most sought-after hotels in Ortigia. Another welcoming option is Le Dimore Del Mito - Atalanta.
How far in advance should I book my Ortigia vacation?
While not all airlines release ticket prices early, you can normally look up international fares on Expedia up to a year in advance. This is the time you can bag some incredible bargains. If you've left everything to the last minute, you might still be in luck. Low prices occasionally emerge a few weeks prior to departure.
What does an Expedia Ortigia travel package include?
You can select from any combination of flights, rental cars and hotels. Once you've made your booking, you can also add on tours and activities. Want to pick your airfare class? That's also possible. The choice is yours when it comes to crafting your dream Ortigia trip.
What should I know before booking an Ortigia travel package?
An Expedia travel package can be tailored to your budget and is a fantastic way to make your budget go further. What you include is totally up to you. Rental cars, hotels and flights — choose any combination that suits your plans.
Can I choose my airline with an Ortigia Expedia vacation package?
Most definitely. We offer more than 550 airlines around the world, so you can customize your Ortigia escape according to your budget and needs.
If I'm not able to travel, can I cancel my Ortigia vacation package?
Whether it's your flight or hotel, you can cancel and rebook it. Booked your Ortigia vacation package in the last 24 hours? You may be able to make any changes for free. For older bookings, you may incur a fee from your airline, hotel or car rental company. For further information, head to our Customer Service Portal. We're here to help you every step of the way.

Discover the most popular places to visit in Ortigia

Tropical Aquarium of Syracuse

You can browse the exhibits at Tropical Aquarium of Syracuse, a museum with a story of its own, during your trip to Syracuse. Wander the seaside in this culturally rich area.

Tropical Aquarium of Syracuse

Teatro dei Pupi

4.5/5(3 reviews)

Enjoy a show at Teatro dei Pupi, a storied theater in Syracuse. Wander the seaside in this culturally rich area.

Teatro dei Pupi

Archaeological Park of Neapolis

4.5/5(40 reviews)

You can learn about the history of Syracuse with a trip to Archaeological Park of Neapolis. Wander the seaside in this culturally rich area.

Archaeological Park of Neapolis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.