Ostiense Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩234,741 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Rome City Centre. Top attractions like Trevi Fountain and Piazza Navona are major draws. Catch the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station to see more of the city.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Aparthotel Colombo Roma

Aparthotel Colombo Roma

4 out of 5
Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
The price is ₩88,207 per night from Jan 20 to Jan 21
₩88,207
₩122,833 total
Jan 20 - Jan 21
includes taxes & fees
9/10 Wonderful! (357 reviews)
Nice welcome, good location, clean hotel

Reviewed on Jan 6, 2026

Aparthotel Colombo Roma
Hotel Dei Mellini

Hotel Dei Mellini

4 out of 5
Via Muzio Clementi 81 Rome RM
Fully refundableReserve now, pay when you stay
The price is ₩285,969 per night from Feb 1 to Feb 2
₩285,969
₩340,371 total
Feb 1 - Feb 2
includes taxes & fees
9.2/10 Wonderful! (987 reviews)
Delightful return to the hotel - very friendly and helpful staff. Excellent breakfast selection.

Reviewed on Jan 11, 2026

Hotel Dei Mellini
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
The price is ₩206,442 per night from Jan 18 to Jan 19
₩206,442
₩252,891 total
Jan 18 - Jan 19
includes taxes & fees
8.6/10 Excellent! (1,922 reviews)
Great location. Hospitality was outstanding very accommodating snacks available and the breakfast was great. Highly recommended certainly will return.

Reviewed on Jan 10, 2026

Hotel Quirinale
See all 15,154 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Ostiense vacation package cost?
Our Ostiense packages, which start at just , are an ideal way to save money. All you have to do is choose your favorite flights, hotels and rental cars to create your perfect escape.
How do I get a cheap travel package to Ostiense?
Browse and book everything in one place with our Ostiense vacation packages. You'll find deals on flights, hotels, tours and more that'll keep your credit card happy and adventurous side satisfied. And, with more than 550 partner airlines and 1,000,000 properties all over the world to choose from, you have countless opportunities to mix and match as you please.
Where should I stay in Ostiense?
Most people who travel to Ostiense include both St. Peters Basilica and Roman Forum on their to-do lists. Why not go for a hotel within walking distance of these main attractions?
What are the top hotels in Ostiense?
Hotel Derby and Rooms Piramide are among the most sought-after hotels in Ostiense. Why not have a look at the rates and amenities at each and then make up your mind?
How far in advance should I book my Ostiense vacation?
Reserving your seat early with Expedia means one less thing to worry about. Most carriers display prices up to 12 months in advance. This is often the cheapest time to book. If circumstances have left you booking late, great deals to Ostiense sometimes emerge just weeks before departure.
What does an Expedia Ostiense travel package include?
Flights, rental cars and hotels — we've got them all. With Expedia, you can create your Ostiense travel package just how you like it. All you have to do is figure out what you need. Once you've made your booking, you can add on extras like experiences and activities. The more you bundle, the greater the savings!
What should I know before booking an Ostiense travel package?
When you book your hotels, flights and car rentals together, you'll walk away with awesome discounts. Whether you're organizing a rural escape in a cottage or prefer to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with an Ostiense Expedia vacation package?
You certainly can. Expedia has access to more than 550 partner airlines throughout the world, so pick the carrier that's a good fit for your budget and traveling style.
If I'm not able to travel, can I cancel my Ostiense vacation package?
You sure can, and we'll help you every step of the way. You may be able to change or cancel your Ostiense vacation package at no cost within 24 hours of booking. But you may be charged a fee by your airline, hotel or car rental company for older bookings. If life gets in the way of your vacation, browse our Customer Service Portal for more information.

Discover the most popular places to visit in Ostiense

Illuminated Colosseum stands majestically in Rome at night with vibrant city life surrounding it

Colosseum

A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.

Colosseum
Visit Trevi Fountain, stunning baroque masterpiece in Rome, Italy under bright blue sky

Trevi Fountain

Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain.

Trevi Fountain
Visit Pantheon in Rome and experience its ancient architecture and bustling atmosphere during a sunny day

Pantheon

One of ancient Rome’s greatest achievements combines momentous history and inspired architecture.

Pantheon
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.