Otay Mesa West Vacations

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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego

Otay Mesa West Hotel Deals

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ₩174,980 per night from Oct 28 to Oct 29
₩174,980
₩201,130 total
Oct 28 - Oct 29
includes taxes & fees
9/10 Wonderful! (168 reviews)
"Beautiful facility. Quiet. Good breakfast"

Reviewed on Oct 17, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ₩313,641 per night from Nov 1 to Nov 2
₩313,641
₩441,561 total
Nov 1 - Nov 2
includes taxes & fees
9/10 Wonderful! (2,857 reviews)
"The hotel is beautiful and conveniently located near Seaport Village, offering everything you need within walking distance. You and your family can fully enjoy your stay without having to venture far—Seaport Village and the hotel itself provide plenty to experience. The dining options are both affordable ..."

Reviewed on Oct 20, 2025

Manchester Grand Hyatt San Diego
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

3.5 out of 5
San Diego
The price is ₩118,788 per night from Nov 11 to Nov 12
₩118,788
₩134,165 total
Nov 11 - Nov 12
includes taxes & fees
7.8/10 Good! (1,075 reviews)
"Nice clean room. Everything was great."

Reviewed on Oct 19, 2025

Comfort Inn San Diego Airport At The Harbor
See all 6,766 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Otay Mesa West vacation package cost?
Discover the best of Otay Mesa West from as little as . Choose from a wonderful selection of flights, hotels and rental cars to suit every style and budget. You can score even better deals when you add some experiences or tours to your package.
How do I get a cheap travel package to Otay Mesa West?
Booking an Otay Mesa West vacation package with Expedia is the easiest way to save. We have over 550 partner airlines and 1,000,000 properties across the globe. With such an awesome range to select from, you'll have no trouble putting together your next dream vacation.
Where should I stay in Otay Mesa West?
You'll want to stay where the action is. Many people book hotels around popular attractions, like Las Americas Premium Outlets, North Island Credit Union Amphitheatre and Aquatica.
How far in advance should I book my Otay Mesa West vacation?
Smart travelers will likely want to book early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you're booking last minute, don't despair. Low prices sometimes appear just weeks before departure dates.
What does an Expedia Otay Mesa West travel package include?
It all depends on what type of getaway you're contemplating. Otay Mesa West vacation deals can include hotels, car rentals and flights. You can mix and match to find the travel package that fits your needs. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking an Otay Mesa West travel package?
Get ready to save with an Expedia travel package. Bundle your airfares, rental cars and hotels and pick up fabulous discounts. You're not limited to hotels, though. Book with us and select from beach villas, mountain cabins and everything in between!
Can I choose my airline with an Otay Mesa West Expedia vacation package?
With a vacation package, you're the boss. Whether you'd like to fly to Otay Mesa West in economy or business class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Otay Mesa West vacation package?
You can. We get that even the best-laid plans can go awry, so we're here to help if you need to make changes to your Otay Mesa West vacation package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for further information. Also, be sure to check your itinerary for the nitty-gritty on change fees.

Discover the most popular places to visit in Otay Mesa West

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
Balboa Park which includes a pond

Balboa Park

Culture and nature converge in this diverse park located in the heart of the city.

Balboa Park
USS Midway Museum which includes military items

USS Midway Museum

Experience the thrills and hardships of Navy life at this waterfront museum which has become a San Diego landmark.

USS Midway Museum
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.