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Our top choices for Otay Mesa West hotels

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,728 reviews)
"Clean, quiet, helpful staff and simple airport transfers. "
United States
Jill
The price is ₩256,738
₩295,107 total
includes taxes & fees
Apr 3 - Apr 4
Hampton Inn & Suites San Diego Airport Liberty Station

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,783 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
9.2 km from Otay Mesa West
9.8 out of 10, Exceptional, (1,112 reviews)
"Great location "
United States
Irma
The price is ₩394,373
₩434,573 total
includes taxes & fees
Mar 16 - Mar 17
Ayres Hotel San Diego South - Chula Vista

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
2.4 km from Otay Mesa West
7.8 out of 10, Good, (1,638 reviews)
"Clean rooms and the breakfast was amazing "
United States
Vanessa
The price is ₩151,298
₩166,428 total
includes taxes & fees
Mar 15 - Mar 16
Best Western Chula Vista/Otay Valley Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,747 reviews)
"My favorite place to stay"
United States
Rubidia
The price is ₩198,213
₩218,415 total
includes taxes & fees
Mar 15 - Mar 16
Best Western Plus Marina Gateway Hotel

Valli Hi Motel

Valli Hi Motel
2.5 star property
2.2 km from Otay Mesa West
8.4 out of 10, Very Good, (1,000 reviews)
"Excelente "
Mexico
Julio
Valli Hi Motel

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
12.4 km from Otay Mesa West
9.6 out of 10, Exceptional, (592 reviews)
"Clean room and friendly staff "
United States
Michael
The price is ₩250,698
₩276,256 total
includes taxes & fees
Mar 23 - Mar 24
SpringHill Suites by Marriott Chula Vista Eastlake

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.4 km from Otay Mesa West
8.4 out of 10, Very Good, (3,370 reviews)
"Love this hotel will always stay here when I come to San Diego "
United States
Darlene
The price is ₩183,259
₩275,153 total
includes taxes & fees
Apr 1 - Apr 2
Sheraton San Diego Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 26.8 km from Otay Mesa West
8.4 out of 10, Very Good, (1,366 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
United States
Dani
The price is ₩352,886
₩483,705 total
includes taxes & fees
Apr 6 - Apr 7
San Diego Mission Bay Resort

Old Town Inn

Old Town Inn
2.5 star property
23.7 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,816 reviews)
"Clean, friendly staff, good value, nice pool area"
Canada
Mark
Old Town Inn

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,070 reviews)
"great stay"
United States
Jose
The price is ₩224,309
₩257,831 total
includes taxes & fees
Mar 29 - Mar 30
Holiday Inn Express San Diego Airport - Old Town by IHG

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
21.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,515 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is ₩335,730
₩385,251 total
includes taxes & fees
Mar 18 - Mar 19
Lafayette Hotel & Club

Pleasant Inn

Pleasant Inn
2.5 star property
30.7 km from Otay Mesa West
8.4 out of 10, Very Good, (1,333 reviews)
"Great stay!"
United States
Gene
The price is ₩137,078
₩157,295 total
includes taxes & fees
Mar 15 - Mar 16
Pleasant Inn

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
2.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,228 reviews)
"Great stay"
United States
Elisa
The price is ₩173,216
₩197,033 total
includes taxes & fees
Mar 18 - Mar 19
Best Western Americana Inn

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
23.2 km from Otay Mesa West
8.4 out of 10, Very Good, (1,001 reviews)
"Room was clean, pleasant staff and great breakfast "
United States
Wendy
The price is ₩174,755
₩192,230 total
includes taxes & fees
Mar 15 - Mar 16
Best Western Plus La Mesa San Diego

The Rambler Hotel

The Rambler Hotel
3.0 star property
8 km from Otay Mesa West
9.0 out of 10, Wonderful, (2,068 reviews)
"Absolutely amazing stay will def be coming back!"
United States
Victor
The price is ₩174,462
₩201,848 total
includes taxes & fees
Mar 30 - Mar 31
The Rambler Hotel

Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
29.7 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,011 reviews)
"Absolutely wonderful hotel. Really great location with a lot of convenient dining and shopping options in the area. "
United States
Maxwell
The price is ₩179,124
₩205,545 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn San Diego-Kearny Mesa

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,205 reviews)
"Good location friendly staff"
United States
Anya
The price is ₩143,821
₩165,314 total
includes taxes & fees
Mar 22 - Mar 23
Wyndham Garden San Diego Near SeaWorld

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
22.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (2,808 reviews)
"Great stay, highly recommend."
United States
Ryan
The price is ₩262,427
₩330,965 total
includes taxes & fees
Apr 5 - Apr 6
Humphreys Half Moon Inn

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
3.0 star property
24.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (718 reviews)
"Great place to stay, nice room Highly recommended !!"
United States
Wilfredo
The price is ₩241,432
₩277,515 total
includes taxes & fees
Mar 24 - Mar 25
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighborhood that travelers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.
Where can I learn more about changing or cancelling my trip to Otay Mesa West?
To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.
What is there to do around this San Diego neighborhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.