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Our top choices for Otay Mesa West hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,685 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
19.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (964 reviews)
"Great stay. Would definitely stay again."
United States
Zoraima
The price is ₩178,881
₩207,405 total
includes taxes & fees
Feb 23 - Feb 24
The DEXTRO Little Italy, BW Premier Collection

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 18.2 km from Otay Mesa West
9.0 out of 10, Wonderful, (2,910 reviews)
"Excellent stay...wonderful staff"
United States
Michelle
The price is ₩349,714
₩485,209 total
includes taxes & fees
Feb 6 - Feb 7
Manchester Grand Hyatt San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very Good, (6,022 reviews)
"Great place to stay"
United States
David
The price is ₩222,632
₩309,052 total
includes taxes & fees
Feb 8 - Feb 9
Wyndham San Diego Bayside

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,162 reviews)
"Good location friendly staff"
United States
Anya
The price is ₩130,228
₩149,690 total
includes taxes & fees
Jan 26 - Jan 27
Wyndham Garden San Diego Near SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld
3.0 star property
24.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (556 reviews)
"Great place to stay, nice room Highly recommended !!"
United States
Wilfredo
The price is ₩184,447
₩212,014 total
includes taxes & fees
Jan 27 - Jan 28
Hampton Inn & Suites by Hilton San Diego SeaWorld

Ash&9th

Ash&9th
2.0 star property
18.5 km from Otay Mesa West
8.4 out of 10, Very Good, (279 reviews)
"Will stay again! "
United States
Darlene
The price is ₩94,818
₩107,855 total
includes taxes & fees
Jan 26 - Jan 27
Ash&9th

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
23.1 km from Otay Mesa West
8.8 out of 10, Excellent, (3,626 reviews)
"Love the Kings Inn, always on our travel list!!"
United States
Linzee
Kings Inn San Diego

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay, 27.2 km from Otay Mesa West
8.4 out of 10, Very Good, (1,594 reviews)
"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."
United States
francisco
The price is ₩218,023
₩328,029 total
includes taxes & fees
Jan 30 - Jan 31
Hyatt Regency Mission Bay Spa and Marina

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 27.9 km from Otay Mesa West
8.8 out of 10, Excellent, (2,385 reviews)
"This is a staple for me and my family whenever we are in the area."
United States
Elizabeth
The price is ₩209,975
₩318,796 total
includes taxes & fees
Feb 22 - Feb 23
Paradise Point Resort & Spa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
11 km from Otay Mesa West
8.0 out of 10, Very Good, (1,609 reviews)
"Yes the room was clean and the staff was nice and very friendly and the breakfast was good it was a good experience."
United States
russell
The price is ₩174,126
₩198,068 total
includes taxes & fees
Jan 26 - Jan 27
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
23.7 km from Otay Mesa West
8.0 out of 10, Very Good, (1,024 reviews)
"Great stay"
United States
Viviann
The price is ₩141,934
₩163,736 total
includes taxes & fees
Feb 8 - Feb 9
Crowne Plaza San Diego - Mission Valley by IHG

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 17.8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,007 reviews)
"Great location and stay. "
United States
Simran
The price is ₩144,861
₩210,248 total
includes taxes & fees
Jan 26 - Jan 27
Staypineapple, Hotel Z, Gaslamp San Diego

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 23.2 km from Otay Mesa West
8.2 out of 10, Very Good, (1,942 reviews)
"Rooms are very clean, workers were very friendly. Will definitely stay there again "
United States
Claudia
The price is ₩145,739
₩167,519 total
includes taxes & fees
Feb 8 - Feb 9
Comfort Inn San Diego Old Town

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
19.3 km from Otay Mesa West
8.2 out of 10, Very Good, (2,362 reviews)
"Room was clean, check in staff was friendly and very helpful. Would definitely stay here again!"
United States
Susan
The price is ₩203,834
₩236,335 total
includes taxes & fees
Feb 7 - Feb 8
Hampton Inn San Diego-Downtown

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 29.3 km from Otay Mesa West
8.0 out of 10, Very Good, (1,922 reviews)
"The staff was very nice and great location"
United States
Curtis
The price is ₩128,505
₩147,710 total
includes taxes & fees
Feb 1 - Feb 2
GreenTree Inn San Diego Mission Bay

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3,262 reviews)
"Great place to stay!"
United States
CINDY
The price is ₩567,590
₩728,121 total
includes taxes & fees
Feb 3 - Feb 4
Hard Rock Hotel San Diego

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
22.1 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,327 reviews)
"Beautiful location, great staff, always a pleasure to stay here"
United States
simona
The price is ₩183,051
₩210,408 total
includes taxes & fees
Jan 26 - Jan 27
Bay Club Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
22.1 km from Otay Mesa West
8.8 out of 10, Excellent, (1,572 reviews)
"Great place.very clean great for family would definitely stay there again."
United States
Joseph
The price is ₩208,365
₩239,505 total
includes taxes & fees
Feb 16 - Feb 17
Best Western Plus Island Palms Hotel & Marina

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
22.9 km from Otay Mesa West
8.0 out of 10, Very Good, (2,447 reviews)
"I'd stay here again. "
United States
Flint A
The price is ₩116,913
₩134,385 total
includes taxes & fees
Jan 27 - Jan 28
Days Inn by Wyndham San Diego Hotel Circle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Ocean Beach Farmers Market, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighborhood that travelers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.
Where can I learn more about changing or cancelling my trip to Otay Mesa West?
To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.
What is there to do around this San Diego neighborhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.