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Find Resorts & Hotels with Spas in Pythagorio

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Check availability on Pythagorio Resorts & Hotels with Spas

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Pythagorio hotels with a spa

Couples treatment rooms, steam room, Turkish bath, body treatments
Erato by Samian Mare

Erato by Samian Mare

Erato by Samian Mare
4.0 star property
Samos
9.2 out of 10, Wonderful, (18)
"Great stay! The staff was very helpful with booking taxis for us. The breakfast was great too!"
United States
Anonymous traveler
The price is ₩190,465
₩213,838 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Erato by Samian Mare
Turkish bath, 2 treatment rooms, manicures and pedicures
Aegeon

Aegeon

Aegeon
3.0 star property
Samos
7.6 out of 10, Good, (19)
"Great pool & outdoor area with a lovely bar"
Australia
Tracey
The price is ₩86,863
₩97,749 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Aegeon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pythagorio Hotel Reviews

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

10/10 Excellent
"Perfect"
David 9-night trip
Posted 3 months ago
Proteas Blu Resort - Adults Only
Doryssa Seaside Resort

Doryssa Seaside Resort

10/10 Excellent
"nice and relaxing hotel very close to Pythagoreio center. "
ilkay 4-night trip
Posted 7 months ago
Doryssa Seaside Resort

Frequently asked questions

Looking for a spa hotel in Pythagorio?
Treat yourself to some pampering and book a hotel with a spa. Check out the historical sites and museums in Pythagorio—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness center, a hair salon, a beach bar, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort.
How many spa hotels are there in Pythagorio?
Among Expedia's 74 accommodation options in Pythagorio, there are 5 spa hotels.
What's there to see and do in Pythagorio?
Take in the sights and attractions that Pythagorio offers with a visit to Samos Pythagorion Archaeological Museum, Pythagoreion, and Glicorisa Beach. If you have extra time while you're in the area, you might want to stop by Castle of Lycurgus and Panagia Spiliani Monastery.
What is a Pythagorio spa hotel?
Spa hotels in Pythagorio feature on-site spas which offer services including therapies and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.