A coastal town with a pier, boats, and a hillside with buildings.

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Check availability on Pythagorio Resorts & Hotels with Spas

Tonight
Sep 22 - Sep 23
Tomorrow
Sep 23 - Sep 24
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Pythagorio hotels with a spa

A modern interior with a central seating area, a kitchen in the background, and large windows.
A spa area with a hot tub, two bean bag chairs, and several potted plants.
An outdoor cafe with tables, chairs, potted plants, and a tree with ripe oranges.
A modern bathroom with a glass-enclosed shower, a marble-tiled wall, a sink with a mirror, and neatly stacked towels.

1. Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
  • Serene massages await at this eco-certified urban retreat with a steam room and rainfall showers for ultimate relaxation.
₩152,720
₩183,047 total
includes taxes & fees
Oct 5 - Oct 6
Doryssa Theorem Hotel
A massage therapy session in an outdoor setting with a scenic view of the sea and mountains.
A serene outdoor setting with a pool, a person in a white dress, and a view of the sea.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.
A modern hotel room with a white sofa, a glass coffee table with cups, a blue desk, and a view of the sea through large windows.

2. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Seaside retreat offers rejuvenating spa treatments, private beach access, and indoor-outdoor pools.
₩232,924
₩278,783 total
includes taxes & fees
Sep 27 - Sep 28
Proteas Blu Resort - Adults Only
A modern bathroom with a stone-patterned wall, a glass bathtub, and a small seating area with a kettle and cups.
A poolside table with a meal, a drink, and a view of a pool and mountains.
A beach with rows of beige lounge chairs and umbrellas, a clear sky, and a calm sea with a distant mountain.
A hotel room with a bed, a sofa, a dining table, and a view of the sea.

3. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
  • Rejuvenate at this beachfront hotel with a full-service spa and seaside yoga classes for total relaxation.
₩261,891
₩310,514 total
includes taxes & fees
Oct 1 - Oct 2
Doryssa Seaside Resort
A person in a colorful swimsuit standing on a balcony overlooking the ocean.
A balcony with a table set for breakfast, including a basket, a plate of pastries, a cup, and a potted plant.
A coastal residential area with multi-story buildings, a swimming pool, and a view of the sea and a mountain in the distance.
A modern living room with a sofa, armchair, and a TV mounted on the wall.

4. Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
  • Revitalize with beachside spa services and seasonal pool at this coastal retreat with Turkish hammam and sauna.
₩149,229
₩179,224 total
includes taxes & fees
Sep 28 - Sep 29
Hydrele Beach Hotel
A pool area with steps leading into the water, a bench, and a stone wall.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.
A room with a view of the sea through sheer curtains, a wooden bed, and a balcony with a chair and a table.

5. Casa Cook Samos

Casa Cook Samos
Samos
  • Immerse in a beachfront boutique escape with 4 specialized treatment rooms and daily aromatherapy spa services for complete renewal.
₩296,023
₩347,904 total
includes taxes & fees
Oct 16 - Oct 17
Casa Cook Samos
A poolside lounge area with wooden pergolas and stone walls.
A room with a balcony, a sofa, a wooden table, and a view of palm trees and mountains.
A pool area with lounge chairs and umbrellas, surrounded by stone walls and greenery.
A wooden deck with lounge chairs and a pool.

6. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
  • Indulge in rejuvenating spa treatments at this boutique hotel with seasonal pool and garden oasis.
₩185,330
₩218,769 total
includes taxes & fees
Oct 1 - Oct 2
Doryssa Boutique Hotel
A circular seating area with mosaic tile walls and a central pillar.
An outdoor patio area with tables and chairs, a pool, and umbrellas.
A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and a clear sky.
A reception area with a wooden reception desk, a clock, and a reception sign.

7. Aegeon

Aegeon
Samos
  • Unwind at this island hotel with tranquil spa treatments, including massage services in 2 treatment rooms and a relaxing Turkish bath.
₩89,144
₩105,528 total
includes taxes & fees
Oct 2 - Oct 3
Aegeon
A spacious lobby with a marble floor, white sofas, and potted plants.
A pool area with a wooden pergola structure, a clear night sky, and a mountain backdrop.
An outdoor dining area with wicker furniture, a bar with shelves of bottles, and a view of trees and mountains in the background.
A wooden deck with lounge chairs and a thatched umbrella.

8. Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa
Samos
  • Serene beachfront escape with two outdoor pools and an on-site spa offering rejuvenating treatments in scenic surroundings.
₩119,492
₩146,850 total
includes taxes & fees
Sep 27 - Sep 28
Samian Mare Hotel Suites & Spa
A poolside area with lounge chairs and an umbrella, overlooking a clear blue sea and distant mountains.
A bedroom with a bed, a large mirror, and an open door leading to a balcony with a view of the sea.
A coastal landscape with trees framing a beach and clear blue sea.
A balcony with a view of a coastal area, including a beach and a mountainous backdrop.

9. Armonia Bay Hotel

Armonia Bay Hotel
Samos
  • Mediterranean retreat offers rejuvenating seaside escapes with massages, infinity pools, and garden serenity.
₩185,476
₩211,054 total
includes taxes & fees
Oct 14 - Oct 15
Armonia Bay Hotel
A modern outdoor terrace with a pool, seating, and a view of a coastal town.
A bar area with stools, a counter, and bottles.
A modern outdoor seating area with a view of a coastal town and mountains.
A modern multi-story house with a flat roof, large windows, and a landscaped terrace with water features.

10. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
₩327,813
₩382,719 total
includes taxes & fees
Oct 20 - Oct 21
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
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Choose what matters most at spa hotels in Pythagorio

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with pools in Pythagorio

A beach with rows of beige lounge chairs and umbrellas, a clear sky, and a calm sea with a distant mountain.
A modern kitchen with a central island, pendant lighting, and a tiled backsplash.
A beachside lounge with white umbrellas and beige lounge chairs, a wooden deck, and a view of the sea and a pier in the background.
A coastal hotel with a swimming pool, surrounded by greenery and overlooking the sea.

Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
₩261,891
₩310,514 total
includes taxes & fees
Oct 1 - Oct 2
Doryssa Seaside Resort
A modern resort with a central pool, lounge areas, and mountain views.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.
A bar area with a wooden counter and stools.

Casa Cook Samos

Casa Cook Samos
Samos
₩296,023
₩347,904 total
includes taxes & fees
Oct 16 - Oct 17
Casa Cook Samos
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.
A covered outdoor seating area with wooden flooring, white cushioned chairs, and tables.
A modern bedroom with a bed, bedside tables, a desk, and a view of the sea.

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
₩232,924
₩278,783 total
includes taxes & fees
Sep 27 - Sep 28
Proteas Blu Resort - Adults Only
A person in a colorful swimsuit standing on a balcony overlooking the ocean.
A beach with clear blue water, a sandy shore, and a few boats. There are buildings with colorful roofs in the background.
A coastal residential area with multi-story buildings, a swimming pool, and a view of the sea and a mountain in the distance.
A buffet area with a variety of food options, including a section labeled "Pastry" and another labeled "Bacon."

Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
₩149,229
₩179,224 total
includes taxes & fees
Sep 28 - Sep 29
Hydrele Beach Hotel
A pool area with lounge chairs and umbrellas, surrounded by stone walls and greenery.
A boutique hotel entrance with a stone pathway, wooden gates, and potted plants.
A wooden deck with lounge chairs and a pool.
A bedroom with a wooden wall, a hanging textured light fixture, and a bed with pillows.

Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
₩185,330
₩218,769 total
includes taxes & fees
Oct 1 - Oct 2
Doryssa Boutique Hotel
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Spa hotels with free breakfast in Pythagorio

A beach with rows of beige lounge chairs and umbrellas, a clear sky, and a calm sea with a distant mountain.
A modern kitchen with a central island, pendant lighting, and a tiled backsplash.
A beachside lounge with white umbrellas and beige lounge chairs, a wooden deck, and a view of the sea and a pier in the background.
A coastal hotel with a swimming pool, surrounded by greenery and overlooking the sea.

Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
₩261,891
₩310,514 total
includes taxes & fees
Oct 1 - Oct 2
Doryssa Seaside Resort
An outdoor cafe with tables, chairs, potted plants, and a tree with ripe oranges.
A modern interior with a central seating area, a kitchen in the background, and large windows.
A spa area with a hot tub, two bean bag chairs, and several potted plants.
A modern kitchen with dark cabinetry, a central island, and two chairs.

Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
₩152,720
₩183,047 total
includes taxes & fees
Oct 5 - Oct 6
Doryssa Theorem Hotel
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.
A covered outdoor seating area with wooden flooring, white cushioned chairs, and tables.
A modern bedroom with a bed, bedside tables, a desk, and a view of the sea.

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
₩232,924
₩278,783 total
includes taxes & fees
Sep 27 - Sep 28
Proteas Blu Resort - Adults Only
A person in a colorful swimsuit standing on a balcony overlooking the ocean.
A beach with clear blue water, a sandy shore, and a few boats. There are buildings with colorful roofs in the background.
A coastal residential area with multi-story buildings, a swimming pool, and a view of the sea and a mountain in the distance.
A buffet area with a variety of food options, including a section labeled "Pastry" and another labeled "Bacon."

Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
₩149,229
₩179,224 total
includes taxes & fees
Sep 28 - Sep 29
Hydrele Beach Hotel
A modern resort with a central pool, lounge areas, and mountain views.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.
A bar area with a wooden counter and stools.

Casa Cook Samos

Casa Cook Samos
Samos
₩296,023
₩347,904 total
includes taxes & fees
Oct 16 - Oct 17
Casa Cook Samos
A pool area with lounge chairs and umbrellas, surrounded by stone walls and greenery.
A boutique hotel entrance with a stone pathway, wooden gates, and potted plants.
A wooden deck with lounge chairs and a pool.
A bedroom with a wooden wall, a hanging textured light fixture, and a bed with pillows.

Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
₩185,330
₩218,769 total
includes taxes & fees
Oct 1 - Oct 2
Doryssa Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pythagorio Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

8/10 Good
"Very good, friendly place"
Zafer 3-night trip
Posted 3 weeks ago
Doryssa Seaside Resort

Frequently asked questions

Looking for a spa hotel in Pythagorio?
Treat yourself to some pampering and book a hotel with a spa. Check out the historical sites and museums in Pythagorio—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness center, a hair salon, a beach bar, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Proteas Blu Resort - Adults Only and Hydrele Beach Hotel.
How many spa hotels are there in Pythagorio?
Among Expedia's 74 accommodation options in Pythagorio, there are 5 spa hotels.
What's there to see and do in Pythagorio?
Take in the sights and attractions that Pythagorio offers with a visit to Samos Pythagorion Archaeological Museum, Pythagoreion, and Glicorisa Beach. If you have extra time while you're in the area, you might want to stop by Folklore Museum of the Nikolaos Dimitriou Foundation of Samos and Tunnel of Eupalinos.
What is a Pythagorio spa hotel?
Spa hotels in Pythagorio feature on-site spas which offer services including therapies and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.