Find hotels near Saint Francis Medical Center, Cape Girardeau from ₩83,982

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 26 - Aug 27
Tomorrow
Aug 27 - Aug 28
This weekend
Aug 29 - Aug 31
Next weekend
Sep 5 - Sep 7

Filter by

Guest rating
Guest rating
Star rating

Compare 184 hotels close to Saint Francis Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Saint Francis Medical Center hotels

Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (740)
"Nice and clean hotel friendly service"
The price is ₩152,360
₩171,884 total
includes taxes & fees
Sep 5 - Sep 6
Hampton Inn Cape Girardeau I 55 East
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is ₩143,120
₩161,459 total
includes taxes & fees
Sep 1 - Sep 2
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (985)
"Easy access and parking"
The price is ₩125,042
₩141,049 total
includes taxes & fees
Aug 31 - Sep 1
Drury Inn & Suites Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (125)
"The hotel was very clean and updated and the staff was super friendly and very informative!"
The price is ₩129,224
₩145,783 total
includes taxes & fees
Sep 4 - Sep 5
Fairfield Inn & Suites by Marriott Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Excellent place to stay "
The price is ₩97,252
₩109,716 total
includes taxes & fees
Aug 28 - Aug 29
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"We enjoyed the quick check in and how quiet the property was. "
The price is ₩97,252
₩109,716 total
includes taxes & fees
Aug 28 - Aug 29
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG
Exterior

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.0 out of 10, Very Good, (838)
"Great stay great staff"
The price is ₩108,382
₩129,912 total
includes taxes & fees
Aug 31 - Sep 1
Candlewood Suites Cape Girardeau by IHG
Town House Inn Cape Giradreau
1 bedroom, desk, free WiFi

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (194)
"Easy to get in and out "
The price is ₩97,266
₩113,621 total
includes taxes & fees
Aug 28 - Aug 29
Town House Inn Cape Giradreau
Rockwood Inn
Standard Room, 1 Queen Bed, Non Smoking, Garden View | 1 bedroom, free WiFi

Rockwood Inn

2.0 star property
10.0 out of 10, Exceptional, (16)
"The property was historic and renovations were perfect. Each room hads a bathroom, the beds were great. It was lovely and peaceful. "
The price is ₩208,816
₩235,564 total
includes taxes & fees
Sep 2 - Sep 3
Rockwood Inn
Courtyard by Marriott Cape Girardeau Downtown
Lobby lounge

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (441)
"Very clean and upscale hotel."
The price is ₩173,689
₩196,813 total
includes taxes & fees
Sep 7 - Sep 8
Courtyard by Marriott Cape Girardeau Downtown
The Riverview
Grand Riverview Two Queen Room | 1 bedroom, premium bedding, pillowtop beds, in-room safe

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (396)
"From the moment we walked in we were impressed with the customer service, facility & cleanliness. We enjoyed every part of our one night stay! We would definitely stay here again "
The price is ₩183,832
₩207,389 total
includes taxes & fees
Sep 7 - Sep 8
The Riverview
Tru By Hilton Cape Girardeau
Room, 2 Queen Beds

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (54)
"Great overall stay"
The price is ₩128,738
₩146,521 total
includes taxes & fees
Sep 1 - Sep 2
Tru By Hilton Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (602)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is ₩108,660
₩117,597 total
includes taxes & fees
Aug 31 - Sep 1
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (729)
"Great area, fast check in, quiet, very spacious"
The price is ₩123,666
₩133,837 total
includes taxes & fees
Aug 31 - Sep 1
Comfort Suites Jackson-Cape Girardeau
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1005)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is ₩125,042
₩132,198 total
includes taxes & fees
Aug 31 - Sep 1
Drury Inn & Suites Jackson MO
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (629)
"Staff was wonderful and helpful pool was great room was comfortable breakfast needs improvements decent for what they had "
The price is ₩83,982
₩94,743 total
includes taxes & fees
Sep 14 - Sep 15
Quality Inn
Town House Inn
Economy Single Room, 1 Queen Bed, Kitchenette | 1 bedroom, free WiFi, bed sheets

Town House Inn

2.5 star property
7.6 out of 10, Good, (407)
"The housekeepers steal and the owners help them and allow it I’m not changing me review Expedia it’s the truth "
The price is ₩90,040
₩97,446 total
includes taxes & fees
Aug 28 - Aug 29
Town House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Saint Francis Medical Center Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Kickback and breakfast was the best I’ve ever had at any hotel before including service. "
Billy R. 1-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's the area like around Saint Francis Medical Center?

Saint Francis Medical Center is located in Cape Girardeau. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, check out the 9 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Saint Francis Medical Center?

Adjacent to Saint Francis Medical Center, Pear Tree Inn Cape Girardeau Near the Medical Center is one of the top choices for your stay based on our traveler data, and this hotel offers free WiFi and LCD TVs. Other good options within a short distance include Drury Plaza Hotel Cape Girardeau Conference Center and Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

How many hotels can I expect to find close to Saint Francis Medical Center?

Expedia has 9 hotels and other accommodations within a mile from Saint Francis Medical Center.

If I need to cancel the hotel reservation for my stay near Saint Francis Medical Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Saint Francis Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Saint Francis Medical Center?

For more information about changing or cancelling your stay near Saint Francis Medical Center, click here.

What can I see and do near Saint Francis Medical Center?

You might spend a leisurely day outdoors at Cape Rock Park and Fort D Historic Site. Create some family memories at Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area.