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Our top choices for Serra Mesa hotels

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1,474 reviews)
"Newly remodeled rooms, clean and wonderful staff. "
United States
Zoe
The Bristol Hotel San Diego

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (1,206 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
United States
Ginger
The price is ₩262,405
₩363,700 total
includes taxes & fees
Jan 25 - Jan 26
Margaritaville Hotel San Diego Gaslamp Quarter

Westgate Hotel

Westgate Hotel
4.5 star property
9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (1,004 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1,003 reviews)
"Great location and stay. "
United States
Simran
The price is ₩130,397
₩193,529 total
includes taxes & fees
Jan 25 - Jan 26
Staypineapple, Hotel Z, Gaslamp San Diego

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 10.1 km from Serra Mesa
9.0 out of 10, Wonderful, (4,025 reviews)
"Great location, friendly attentive staff and great tv setup in rooms."
United States
John
The price is ₩232,956
₩301,450 total
includes taxes & fees
Jan 25 - Jan 26
The Dana on Mission Bay

Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 10.1 km from Serra Mesa
8.6 out of 10, Excellent, (2,195 reviews)
"Excellent location, wonderful staff."
United States
phuc
The price is ₩183,141
₩212,341 total
includes taxes & fees
Jan 25 - Jan 26
Palihotel San Diego Gaslamp Quarter

The Wayfarer San Diego

The Wayfarer San Diego
4.0 star property
Mission Beach, 10.9 km from Serra Mesa
9.4 out of 10, Exceptional, (1,722 reviews)
"Great location. Easy access to beach and boardwalk."
United States
Fernando
The price is ₩235,153
₩270,297 total
includes taxes & fees
Jan 25 - Jan 26
The Wayfarer San Diego

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3,259 reviews)
"Great place to stay!"
United States
CINDY
The price is ₩671,330
₩848,442 total
includes taxes & fees
Feb 3 - Feb 4
Hard Rock Hotel San Diego

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,257 reviews)
"Friendly staff, great location, excellent value overall "
United States
Maryann
The price is ₩233,249
₩270,440 total
includes taxes & fees
Jan 26 - Jan 27
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Inn By The Sea La Jolla

Inn By The Sea La Jolla
3.5 star property
13.7 km from Serra Mesa
9.4 out of 10, Exceptional, (1,775 reviews)
"A lovely stay in a quaint area!"
United States
Sydney
The price is ₩233,791
₩268,734 total
includes taxes & fees
Jan 25 - Jan 26
Inn By The Sea La Jolla

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,901 reviews)
"Excellent location, top notch service and well priced hotel parking!"
Canada
Monika
La Pensione Hotel

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
5.8 km from Serra Mesa
9.2 out of 10, Wonderful, (2,942 reviews)
"Great relaxing hotel"
United States
Christopher
The price is ₩236,032
₩271,307 total
includes taxes & fees
Jan 25 - Jan 26
Legacy Resort Hotel & Spa

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1,025 reviews)
"Loved the staff very welcoming. Room was good and comfortable. Perfect location. This is our 3rd time here and definitely will come back. "
United States
SONIA
The price is ₩174,350
₩198,323 total
includes taxes & fees
Jan 25 - Jan 26
Gaslamp Plaza Suites

Pacific View Inn

Pacific View Inn
2.0 star property
North Pacific Beach, 11.1 km from Serra Mesa
8.0 out of 10, Very Good, (1,004 reviews)
"Room was very clean and the ocean view was spectacular"
United States
Peter
The price is ₩164,564
₩185,867 total
includes taxes & fees
Jan 26 - Jan 27
Pacific View Inn

PB Surf Beachside Inn

PB Surf Beachside Inn
2.5 star property
North Pacific Beach, 11.1 km from Serra Mesa
8.2 out of 10, Very Good, (1,001 reviews)
"Really nice place to stay at"
United States
Alejandro
The price is ₩133,180
₩150,420 total
includes taxes & fees
Jan 25 - Jan 26
PB Surf Beachside Inn

The Shoal La Jolla Beach

The Shoal La Jolla Beach
2.5 star property
13.2 km from Serra Mesa
8.8 out of 10, Excellent, (1,001 reviews)
"Super solid place to stay, clean, great staff, walk to the beach."
United Kingdom
Nick
The price is ₩170,277
₩192,319 total
includes taxes & fees
Jan 26 - Jan 27
The Shoal La Jolla Beach

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1,713 reviews)
"Clean rooms, and very nice staff"
United States
Guadalupe
The price is ₩181,453
₩245,333 total
includes taxes & fees
Feb 16 - Feb 17
The Sofia Hotel

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
12.3 km from Serra Mesa
9.2 out of 10, Wonderful, (2,744 reviews)
"Great stay, highly recommend."
United States
Ryan
The price is ₩247,607
₩313,915 total
includes taxes & fees
Jan 24 - Jan 25
Humphreys Half Moon Inn

Del Mar Beach Hotel

Del Mar Beach Hotel
2.0 star property
21.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1,005 reviews)
"Great place"
United States
Frank
Del Mar Beach Hotel

Empress Hotel of La Jolla

Empress Hotel of La Jolla
3.0 star property
13.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location"
United States
Rachel
The price is ₩246,473
₩308,567 total
includes taxes & fees
Jan 26 - Jan 27
Empress Hotel of La Jolla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Ocean Beach Farmers Market, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels will I be able to find in the Serra Mesa area?
Expedia has 36 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.
Where can I learn more about changing or cancelling my trip to Serra Mesa?
For more information about picking new dates or cancelling your trip to Serra Mesa, click here.
What can I see and do in this San Diego neighborhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.