Serra Mesa, CA
San Diego
Visit Serra Mesa
Popular places to visit

San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.

Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.

Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.

SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Serra Mesa Hotel Deals

Hampton Inn & Suites by Hilton San Diego SeaWorld
Reviewed on Oct 17, 2025

Manchester Grand Hyatt San Diego
Reviewed on Oct 17, 2025

Comfort Inn San Diego Airport At The Harbor
Reviewed on Oct 18, 2025

Handlery Hotel
Reviewed on Oct 18, 2025

Wyndham San Diego Bayside
Reviewed on Oct 18, 2025

Pendry San Diego
Reviewed on Oct 15, 2025
Other neighborhoods around Serra Mesa

Mission Valley
Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.

North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Old Town San Diego
The ample dining options and beautiful seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Mid-City
If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.

Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.