Find hotels in Serra Mesa, San Diego from ₩105,113

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Discover 8,824 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham San Diego Bayside
Enjoy dining under the shade of a palm tree in our outdoor dining area, surrounded by a beautifully landscaped garden.

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very Good, (5799)
"Great stay!"
The price is ₩211,408
₩284,995 total
includes taxes & fees
Sep 1 - Sep 2
Wyndham San Diego Bayside
Hard Rock Hotel San Diego
Relax by the pool surrounded by lounge chairs and umbrellas.

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2778)
"Amazing stay"
The price is ₩229,096
₩329,512 total
includes taxes & fees
Aug 25 - Aug 26
Hard Rock Hotel San Diego
Loews Coronado Bay Resort
Enjoy waterfront views and access to a marina with boats available for recreational use.

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1013)
"Loved our stay very accommodating "
The price is ₩276,505
₩370,155 total
includes taxes & fees
Sep 1 - Sep 2
Loews Coronado Bay Resort
Palihotel San Diego Gaslamp Quarter
Relax on the rooftop with striped sofas and armchairs, surrounded by lush greenery and city views.

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1586)
"Great hotel highly recommended"
The price is ₩131,305
₩191,135 total
includes taxes & fees
Aug 27 - Aug 28
Palihotel San Diego Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
Relax and socialize in our elegantly furnished bar area, featuring a variety of seating options and a selection of beverages.

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2434)
"Loved the history of the hotel and the location to the Gaslamp area."
The price is ₩192,789
₩260,748 total
includes taxes & fees
Aug 17 - Aug 18
The Horton Grand, Downtown/Gaslamp Quarter
Best Western Plus Marina Gateway Hotel
Two large beds with blue and white bedding, a desk, and a potted plant adorn this stylish room.

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3176)
"This location was great for our family get away"
The price is ₩198,847
₩219,120 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Plus Marina Gateway Hotel
Gaslamp Plaza Suites
Experience the grandeur of our lobby, featuring a stunning chandelier, elegant marble floor, and a beautifully designed reception desk.

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1005)
"I love their clean bathrooms and been able to choose a suite over a standard room also been "
The price is ₩151,452
₩172,277 total
includes taxes & fees
Aug 7 - Aug 8
Gaslamp Plaza Suites
Alma San Diego Downtown, a Tribute Portfolio Hotel
Enjoy a city view from the large window, with a desk and chair for work and a small table for relaxation.

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (726)
"Friendly staff and parking was easy "
The price is ₩247,326
₩399,531 total
includes taxes & fees
Aug 17 - Aug 18
Alma San Diego Downtown, a Tribute Portfolio Hotel
El Cordova Hotel on Coronado Island
Enter a spacious lobby with high ceilings and a warm atmosphere, featuring a staircase and lush greenery.

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1005)
"Loved our stay at El Cordova Hotel! The on-site restaurant was super convenient, the whole place had a cozy, homey vibe, and we were just minutes from Coronado Beach. Excellent experience all around!"
The price is ₩351,855
₩387,717 total
includes taxes & fees
Sep 1 - Sep 2
El Cordova Hotel on Coronado Island
The Bristol Hotel San Diego
Welcome to The Bristol, featuring a sleek glass facade and modern design.

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very Good, (1352)
"Very friendly staff all around."
The price is ₩204,836
₩237,098 total
includes taxes & fees
Aug 24 - Aug 25
The Bristol Hotel San Diego
Legacy Resort Hotel & Spa
Welcome to our hotel, set amidst beautifully maintained gardens with a clear path leading to the main building.

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2869)
"Great stay"
The price is ₩233,500
₩268,396 total
includes taxes & fees
Aug 24 - Aug 25
Legacy Resort Hotel & Spa
The Dana on Mission Bay
Relax by the serene pool surrounded by lounge chairs and umbrellas, adjacent to a well-lit building with large windows.

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (3610)
"Wonderful place!"
The price is ₩230,096
₩264,485 total
includes taxes & fees
Aug 17 - Aug 18
The Dana on Mission Bay
The Sofia Hotel
Enter The Sofia Hotel through a grand, arched doorway surrounded by lush topiary and a warm, inviting glow.

The Sofia Hotel

3.5 star property
8.4 out of 10, Very Good, (1508)
"Great stay"
The price is ₩166,663
₩225,982 total
includes taxes & fees
Aug 25 - Aug 26
The Sofia Hotel
Bay Club Hotel & Marina
Enjoy a tranquil marina view from your balcony, complete with a table for two.

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2758)
"Great place to stay"
The price is ₩211,338
₩242,923 total
includes taxes & fees
Sep 1 - Sep 2
Bay Club Hotel & Marina
La Pensione Hotel
La Pensione Hotel features a classic tower with a pointed roof and balcony, set amidst a lively street scene with outdoor seating areas.

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1784)
"Stayed here a few times, always a great getaway. "
The price is ₩198,833
₩226,173 total
includes taxes & fees
Aug 31 - Sep 1
La Pensione Hotel
La Quinta Inn by Wyndham San Diego - Miramar
Welcome to the hotel's reception area, featuring a central desk with a flat top and a stunning cityscape mural above.

La Quinta Inn by Wyndham San Diego - Miramar

3.0 star property
7.6 out of 10, Good, (1007)
"Nice stay"
The price is ₩137,558
₩158,108 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta Inn by Wyndham San Diego - Miramar
Staypineapple, Hotel Z, Gaslamp San Diego
Relax in a stylish room with a large bed, wooden headboard, and cozy armchair.

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Great place"
The price is ₩187,787
₩257,519 total
includes taxes & fees
Sep 1 - Sep 2
Staypineapple, Hotel Z, Gaslamp San Diego
Days Inn by Wyndham San Diego Hotel Circle
Relax by the serene pool surrounded by lounge chairs and umbrellas, set amidst tall trees and a hilly landscape.

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
7.8 out of 10, Good, (2272)
"Great stay. "
The price is ₩136,307
₩156,678 total
includes taxes & fees
Sep 2 - Sep 3
Days Inn by Wyndham San Diego Hotel Circle
Glorietta Bay Inn Coronado Island
Experience the classic charm of this elegant hotel, featuring a grand facade with evenly spaced windows and a central entrance, surrounded by lush greenery and a well-maintained lawn.

Glorietta Bay Inn Coronado Island

3.5 star property
8.6 out of 10, Excellent, (1002)
"Excellent staff and location."
The price is ₩329,513
₩428,206 total
includes taxes & fees
Aug 10 - Aug 11
Glorietta Bay Inn Coronado Island
Days Inn by Wyndham San Diego-East/El Cajon
Relax in this serene space with a large bed, ocean-inspired artwork, and a cozy reading nook by the window.

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1000)
"Cozy bed, very quiet and convenient"
The price is ₩140,545
₩154,874 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn by Wyndham San Diego-East/El Cajon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
US Grant Hotel
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Belmont Park showing rides and a garden
Mission Beach map

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach Park showing a beach
Pacific Beach map

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Gaslamp Quarter showing signage, night scenes and street scenes
Gaslamp Quarter map

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach
Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

San Diego Marriott La Jolla

San Diego Marriott La Jolla

10/10 Excellent
"I like how nice the hotel is in terms of its location relative to being able to access the beaches around La Jolla and Del Mar"
Matthew 1-night trip
Posted 7 hours ago
San Diego Marriott La Jolla

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 36 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.