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Our top choices for Serra Mesa hotels

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 5.3 km from Serra Mesa
8.4 out of 10, Very Good, (1,000 reviews)
"Clean, very chill easy check in"
United States
Susana
The price is ₩131,814
₩148,615 total
includes taxes & fees
Mar 15 - Mar 16
Berkshire Motor Hotel

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,275 reviews)
"Great location, clean rooms, friendly staff"
United States
Beth
Urban Boutique Hotel

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1,026 reviews)
"Clean quiet friendly helpful staff convenient location will stay there again"
United States
David
The price is ₩183,087
₩208,262 total
includes taxes & fees
Apr 5 - Apr 6
Gaslamp Plaza Suites

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very Good, (1,965 reviews)
"Great stay"
United States
Lizeth
The price is ₩153,190
₩176,084 total
includes taxes & fees
Mar 18 - Mar 19
GreenTree Inn San Diego Mission Bay

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,929 reviews)
"Great location and staff "
United States
morgan
La Pensione Hotel

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1,316 reviews)
"Clean room, staff was great during check in and checking out. "
United States
Amber
The price is ₩88,006
₩101,158 total
includes taxes & fees
Mar 26 - Mar 27
Heritage Inn San Diego

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.2 out of 10, Very Good, (407 reviews)
"Great location… stuff was really friendly "
United States
Aurora
The price is ₩115,611
₩131,507 total
includes taxes & fees
Apr 7 - Apr 8
Ash&9th

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,181 reviews)
"Good location friendly staff"
United States
Anya
The price is ₩143,821
₩165,314 total
includes taxes & fees
Mar 22 - Mar 23
Wyndham Garden San Diego Near SeaWorld

SureStay Hotel by Best Western San Diego Pacific Beach

SureStay Hotel by Best Western San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very Good, (1,557 reviews)
"Room was nice, clean, staff was friendly, "
United States
philip
The price is ₩154,802
₩174,841 total
includes taxes & fees
Mar 30 - Mar 31
SureStay Hotel by Best Western San Diego Pacific Beach

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3,470 reviews)
"Nice beds and breakfast, really convenient "
Canada
Margarita
The price is ₩150,604
₩173,112 total
includes taxes & fees
Apr 5 - Apr 6
Comfort Inn Sea World Area

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1,795 reviews)
"Great hotel "
United States
Alexander
The Sofia Hotel

The Beau Hotel Gaslamp Quarter San Diego

The Beau Hotel Gaslamp Quarter San Diego
3.0 star property
Gaslamp Quarter, 9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (640 reviews)
"Clean room, friendly staff, great location."
United States
Bruce
The price is ₩224,267
₩255,103 total
includes taxes & fees
Apr 6 - Apr 7
The Beau Hotel Gaslamp Quarter San Diego

Westgate Hotel

Westgate Hotel
4.5 star property
9.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,002 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
12.2 km from Serra Mesa
8.6 out of 10, Excellent, (1,020 reviews)
"Super clean rooms and a great location "
United States
Mark
Sea Harbor Hotel

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1,519 reviews)
"Great stay, great location, great staff."
United States
Jodie
The Bristol Hotel San Diego

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
11.9 km from Serra Mesa
7.8 out of 10, Good, (1,350 reviews)
"Great room, clean property and courteous staff"
United States
Reginald D.
The price is ₩145,709
₩164,571 total
includes taxes & fees
Apr 6 - Apr 7
Comfort Inn San Diego Airport At The Harbor

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
North Pacific Beach, 7.4 km from Serra Mesa
8.0 out of 10, Very Good, (1,490 reviews)
"Great staff, clean rooms "
United States
Hala
The price is ₩176,709
₩203,161 total
includes taxes & fees
Apr 5 - Apr 6
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.4 km from Serra Mesa
8.6 out of 10, Excellent, (1,456 reviews)
"Great breakfast-comfortable rooms-helpful staff-great location for events"
United States
bill
The price is ₩183,383
₩210,789 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn San Diego/Mission Valley

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
11.8 km from Serra Mesa
8.4 out of 10, Very Good, (1,767 reviews)
"Well stay again love the location"
United States
Lynette
The price is ₩152,471
₩174,961 total
includes taxes & fees
Mar 30 - Mar 31
Best Western Yacht Harbor Hotel

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,291 reviews)
"Clean room, friendly staff, great location Very affordable rate Good breakfast variety "
United States
Mary
The price is ₩210,601
₩244,181 total
includes taxes & fees
Apr 2 - Apr 3
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels will I be able to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.
Where can I learn more about changing or cancelling my trip to Serra Mesa?
For more information about picking new dates or cancelling your trip to Serra Mesa, click here.
What can I see and do in this San Diego neighborhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.