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Find hotels in San Francisco, Panama City from ₩133,516

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Discover 1,555 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Daily cooked-to-order breakfast (USD 15.00 per person)
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1004)
"Good staff, near to the airport"
Mexico
Samuel Edmundo Villa
The price is ₩181,237
₩199,361 total
includes taxes & fees
Nov 15 - Nov 16
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, pool umbrellas, sun loungers
Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6 out of 10, Exceptional, (1087)
"Good place to stay, convenient and the service was very good "
United States
Jannette
The price is ₩155,694
₩171,263 total
includes taxes & fees
Nov 2 - Nov 3
Ramada Plaza by Wyndham Panama Punta Pacifica
Exterior
Aloft Panama
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (871)
"I didbt park ot had breakfast at the hotel"
United States
Karlene
The price is ₩166,253
₩182,879 total
includes taxes & fees
Nov 12 - Nov 13
Aloft Panama
Terrace/patio
Sheraton Grand Panama
Sheraton Grand Panama
4.0 star property
8.6 out of 10, Excellent, (969)
"Centrally located and friendly staff "
United States
Julio
The price is ₩191,898
₩211,088 total
includes taxes & fees
Nov 9 - Nov 10
Sheraton Grand Panama
Front of property
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very Good, (1163)
"Great stay "
United States
Mark
The price is ₩184,627
₩203,090 total
includes taxes & fees
Nov 21 - Nov 22
Megapolis Hotel Panamá
View from property
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 star property
9.4 out of 10, Exceptional, (2125)
"great property and staff "
United States
Yunior
The price is ₩224,673
₩247,140 total
includes taxes & fees
Nov 12 - Nov 13
Plaza Paitilla Inn Hotel
Outdoor pool
Boutique Apartments Panamá Coco del Mar
Boutique Apartments Panamá Coco del Mar
3.5 star property
7.4 out of 10, Good, (146)
"GORGEOUS view!!! And very spacious "
United States
christine
The price is ₩60,900
₩257,684 total
includes taxes & fees
Nov 12 - Nov 13
Boutique Apartments Panamá Coco del Mar
4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama
JW Marriott Panama
5.0 star property
9.0 out of 10, Wonderful, (1011)
"The rooms were amazing "
United States
Andrae Kevin
The price is ₩333,568
₩366,925 total
includes taxes & fees
Nov 14 - Nov 15
JW Marriott Panama
Outdoor pool
Boutique Apartments Atlapa
Boutique Apartments Atlapa
3.0 star property
7.6 out of 10, Good, (23)
"Property was nice, however needs to be exterminated as it has a serious roach problem. We saw roaches everyday. Called to inform and I think they may have come to spray while we were out but that only seemed to make it worse."
United States
Dilworth Ann
Boutique Apartments Atlapa
Exterior
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4.0 star property
8.6 out of 10, Excellent, (1382)
"Very nice Hotel "
United States
Marcos
The price is ₩121,378
₩133,516 total
includes taxes & fees
Nov 2 - Nov 3
Decapolis Hotel Panama City
View from property
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4.0 star property
9.0 out of 10, Wonderful, (1027)
"The hotel was amazing and the view was awesome. The staff was great and the housekeeping as well."
United States
Marcus
The price is ₩191,428
₩210,571 total
includes taxes & fees
Nov 12 - Nov 13
Las Americas Golden Tower Panama
Lobby sitting area
San Francisco by Wynwood House
San Francisco by Wynwood House
3.0 star property
9.2 out of 10, Wonderful, (52)
"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "
United States
mario
The price is ₩155,837
₩210,774 total
includes taxes & fees
Nov 19 - Nov 20
San Francisco by Wynwood House
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (522)
"Great experience "
United States
Jazzmine
The price is ₩217,728
₩239,501 total
includes taxes & fees
Nov 14 - Nov 15
Residence Inn by Marriott Panama City
Outdoor pool
Wanders Panama by Boutique Apartments
Wanders Panama by Boutique Apartments
4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is ₩182,561
₩419,618 total
includes taxes & fees
Nov 16 - Nov 17
Wanders Panama by Boutique Apartments
Terrace/patio
Casa Orquídea
Casa Orquídea
2.0 star property
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
United States
Natalia
The price is ₩131,653
₩144,818 total
includes taxes & fees
Nov 12 - Nov 13
Casa Orquídea
Apartment | Internet
w Bright 1BR w Private Balcony in San Francisco
w Bright 1BR w Private Balcony in San Francisco
2.0 star property
The price is ₩142,216
₩198,939 total
includes taxes & fees
Nov 9 - Nov 10
w Bright 1BR w Private Balcony in San Francisco
Apartment | 1 bedroom, Internet
w Premium 1BR w Balcony in San Francisco
w Premium 1BR w Balcony in San Francisco
2.0 star property
The price is ₩138,782
₩195,161 total
includes taxes & fees
Nov 2 - Nov 3
w Premium 1BR w Balcony in San Francisco
Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4.0 star property
8.4 out of 10, Very Good, (2280)
"Good place right next to the airport"
United States
alejandro
The price is ₩169,074
₩209,593 total
includes taxes & fees
Nov 1 - Nov 2
Crowne Plaza Panama Airport by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo
Central Hotel Panama Casco Viejo
4.0 star property
9.2 out of 10, Wonderful, (1001)
"This Hotel is amazing! From the greetings at check in to the good bye at check out the staff were very attentive and amazing. The hotel has 4 restaurants each one with a different theme and food selection; we tried all and the food, prices, and staff were beyond of amazing. Hotel is in the center of Casco Viejo, very close to all attractions. Thank you the staff and I will definitely will recommend."
United States
Joel
The price is ₩409,698
₩450,668 total
includes taxes & fees
Nov 18 - Nov 19
Central Hotel Panama Casco Viejo
Outdoor pool, sun loungers
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (4453)
"Great stay, clean, great restaurants, nearby for business travels"
United States
Christian
The price is ₩168,621
₩185,483 total
includes taxes & fees
Nov 13 - Nov 14
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

10/10 Excellent
"Clean room, excelent breakfast, good driver for the transportation, excellent staff, very kind"
LUIS F 4-night trip
Posted 1 day ago
Plaza Paitilla Inn Hotel

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels will I find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 210 San Francisco hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.
What is there to do in this Panama City neighborhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.