Find hotels in Santa Ana, Antigua Guatemala from ₩41,207

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Oct 31 - Nov 1
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Discover 1,219 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Interior
Casa Buho B&B
Casa Buho B&B
3.0 star property
9.2 out of 10, Wonderful, (46)
"All was very good and True to the pictures "
United States
Xavier
The price is ₩93,301
₩113,827 total
includes taxes & fees
Nov 28 - Nov 29
Casa Buho B&B
Garden view
Hostal Casa Buho
Hostal Casa Buho
3.0 star property
8.6 out of 10, Excellent, (21)
"Las instalaciones están muy bien solo que sí está lejos del centro de Antigua "
Mexico
LUIS FERNANDO
Hostal Casa Buho
Front of property
Villas Santa Ana-Ricardo
Villas Santa Ana-Ricardo
3.5 star property
8.4 out of 10, Very Good, (11)
"We loved this house the view was wonderful "
United States
Emely
Villas Santa Ana-Ricardo
Living area
La guarida del caudillo
La guarida del caudillo
1.0 star property
The price is ₩39,246
₩47,881 total
includes taxes & fees
Nov 5 - Nov 6
La guarida del caudillo
Living area
Castillo De Los Gigantes
Castillo De Los Gigantes
2.0 star property
The price is ₩33,776
₩41,207 total
includes taxes & fees
Nov 5 - Nov 6
Castillo De Los Gigantes
Indoor wedding
Barceló Guatemala City
Barceló Guatemala City
4.5 star property
9.2 out of 10, Wonderful, (3073)
"Good hotel very close to airport"
United States
Robert
The price is ₩157,238
₩191,831 total
includes taxes & fees
Nov 28 - Nov 29
Barceló Guatemala City
3 outdoor pools, pool umbrellas
Hotel Soleil La Antigua
Hotel Soleil La Antigua
4.0 star property
8.6 out of 10, Excellent, (1002)
"It is a family hotel. "
United States
Pablo
Hotel Soleil La Antigua
Fitness studio
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 star property
9.2 out of 10, Wonderful, (1006)
"Will definitely be returning here!"
United States
Axel
The price is ₩383,662
₩485,403 total
includes taxes & fees
Nov 28 - Nov 29
Hotel Museo Spa Casa Santo Domingo
Terrace/patio
Los Pasos Boutique Hotel & Spa
Los Pasos Boutique Hotel & Spa
4.5 star property
9.4 out of 10, Exceptional, (1005)
"It a beautiful property and everyone was extremely polite, attentive and accommodating! This property is walking distance from the cathedral and main square. Very safe area. Thank you all for your kindness we will be back!"
United States
Maritza
The price is ₩187,858
₩229,187 total
includes taxes & fees
Nov 30 - Dec 1
Los Pasos Boutique Hotel & Spa
Egyptian cotton sheets, premium bedding, in-room safe, desk
El Convento Boutique Hotel
El Convento Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (781)
"El Convento is a beautiful and charming hotel with great service and views of the volcanoes; would definitely stay here again!"
United States
Christine
The price is ₩283,340
₩367,140 total
includes taxes & fees
Nov 16 - Nov 17
El Convento Boutique Hotel
Breakfast, lunch, dinner served; international cuisine, garden views
Clarion Suites Guatemala City
Clarion Suites Guatemala City
4.0 star property
9.0 out of 10, Wonderful, (1002)
"Excellent hotel !! "
United States
Sergio
The price is ₩149,202
₩182,026 total
includes taxes & fees
Nov 28 - Nov 29
Clarion Suites Guatemala City
4 restaurants, breakfast, lunch, dinner served; international cuisine
InterContinental Real Guatemala by IHG
InterContinental Real Guatemala by IHG
5.0 star property
9.2 out of 10, Wonderful, (1010)
"Love everything about this hotel "
United States
Sady
The price is ₩241,841
₩312,504 total
includes taxes & fees
Nov 23 - Nov 24
InterContinental Real Guatemala by IHG
Outdoor pool
Hyatt Centric Guatemala City
Hyatt Centric Guatemala City
4.5 star property
9.6 out of 10, Exceptional, (762)
"Excelente Hotel "
Mexico
Blanca
The price is ₩230,393
₩281,079 total
includes taxes & fees
Nov 14 - Nov 15
Hyatt Centric Guatemala City
Exterior
Naif Boutique Hotel
Naif Boutique Hotel
3.0 star property
8.8 out of 10, Excellent, (357)
"My stay was pleasant "
United States
Ibelisse
The price is ₩159,242
₩194,275 total
includes taxes & fees
Nov 10 - Nov 11
Naif Boutique Hotel
2 treatment rooms
Hotel Las Americas
Hotel Las Americas
4.0 star property
8.4 out of 10, Very Good, (1001)
"The breakfast is great. "
United States
Darrol
The price is ₩122,999
₩150,059 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Las Americas
Exterior
All Suite El Marques de Antigua
All Suite El Marques de Antigua
3.5 star property
9.2 out of 10, Wonderful, (285)
"Had a wonderful stay! The location was perfect for sightseeing, and the hotel staff made us feel at home. Rooms were clean, spacious, and had all the amenities we needed. I highly recommend it"
United States
juan
All Suite El Marques de Antigua
Front of property
Mestizo Cortijo
Mestizo Cortijo
3.0 star property
9.0 out of 10, Wonderful, (85)
"The Hotel it’s super nice! Too bad we couldn’t enjoy the morning sunrise breakfast views because we had to leave super early for our daily activities. "
United States
sujey
The price is ₩176,372
₩215,174 total
includes taxes & fees
Nov 30 - Dec 1
Mestizo Cortijo
Exterior
Hotel Posada de Don Rodrigo Antigua
Hotel Posada de Don Rodrigo Antigua
3.5 star property
9.4 out of 10, Exceptional, (629)
"Lovely hotel, good food. "
United Kingdom
Lucy
The price is ₩228,918
₩313,952 total
includes taxes & fees
Nov 13 - Nov 14
Hotel Posada de Don Rodrigo Antigua
Terrace/patio
In & Out Hotel
In & Out Hotel
3.0 star property
8.4 out of 10, Very Good, (783)
"Breakfast included "
United States
Chelsea
In & Out Hotel
Exterior
Hotel Casa Carmina
Hotel Casa Carmina
4.0 star property
9.0 out of 10, Wonderful, (183)
"Great place to stay the staff were very friendly and welcoming "
United States
Vanessa Sanchez
The price is ₩172,579
₩210,547 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Casa Carmina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

10/10 Excellent
"Tremendous. We'll be back!! "
Robert 2-night trip
Posted 1 day ago
Hotel Museo Spa Casa Santo Domingo

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Frequently asked questions

What's it like in Santa Ana?
Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favorite hotel to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 18 hotels and other accommodations in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about updating your trip to Santa Ana or cancelling it, click here.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.