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Compare 1,487 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Riande Aeropuerto Hotel & Casino
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1887)
"Place was perfect, staff was friendly, service was great, and we will stay there again"
The price is ₩201,350
₩221,485 total
includes taxes & fees
Sep 8 - Sep 9
Riande Aeropuerto Hotel & Casino
Courtyard by Marriott Panama Metromall
Breakfast, lunch, dinner served; international cuisine

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1006)
"Lovely hotel in a great and safe location"
The price is ₩136,163
₩149,780 total
includes taxes & fees
Sep 6 - Sep 7
Courtyard by Marriott Panama Metromall
Panama House Bed & Breakfast
Terrace/patio

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (170)
"The accommodations offered great value for the money. We appreciated the ability to bring our golden retriever, and have a parking spot in front. The owner and her staff were very friendly and helpful. The back area of the property, featuring green parrots and a blue macaw, added ambience and fun to the experience."
The price is ₩57,338
₩63,072 total
includes taxes & fees
Aug 20 - Aug 21
Panama House Bed & Breakfast
Hotel Marparaiso
Exterior

Hotel Marparaiso

3.0 star property
8.0 out of 10, Very Good, (129)
"Everything was good. "
The price is ₩50,468
₩55,520 total
includes taxes & fees
Aug 20 - Aug 21
Hotel Marparaiso
Arcadia Condo Suites
50-inch LED TV with satellite channels

Arcadia Condo Suites

2.5 star property
9.2 out of 10, Wonderful, (53)
"its a very nice place "
The price is ₩67,734
₩138,633 total
includes taxes & fees
Aug 20 - Aug 21
Arcadia Condo Suites
Waymore Hotel Spa & Casino
Outdoor pool

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (420)
"Great hotel for the price."
The price is ₩112,414
₩123,655 total
includes taxes & fees
Aug 20 - Aug 21
Waymore Hotel Spa & Casino
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | 1 bedroom, premium bedding, minibar, in-room safe

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (598)
"The staff was very friendly. "
The price is ₩294,783
₩324,261 total
includes taxes & fees
Sep 7 - Sep 8
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Hotel Acapulco
Classic Double Room, 1 Double Bed, Non Smoking | In-room safe, desk, soundproofing, free WiFi

Hotel Acapulco

3.0 star property
7.6 out of 10, Good, (111)
"Good service "
The price is ₩38,870
₩42,757 total
includes taxes & fees
Aug 20 - Aug 21
Hotel Acapulco
The Westin Panama
Outdoor pool, pool umbrellas, sun loungers

The Westin Panama

4.0 star property
8.8 out of 10, Excellent, (288)
"Restaurant was under construction and food nearby was t the best but the hotel itself and staff were fantastic. "
The price is ₩249,479
₩274,427 total
includes taxes & fees
Aug 30 - Aug 31
The Westin Panama
Hotel Pension Corona
Ecotours

Hotel Pension Corona

2.5 star property
7.8 out of 10, Good, (105)
"Great spot for the price "
The price is ₩25,234
₩27,760 total
includes taxes & fees
Aug 20 - Aug 21
Hotel Pension Corona
Toscana Inn
Terrace/patio

Toscana Inn

3.5 star property
9.0 out of 10, Wonderful, (718)
"Great hotel"
The price is ₩68,706
₩75,577 total
includes taxes & fees
Aug 20 - Aug 21
Toscana Inn
Hotel Milan
Exterior

Hotel Milan

3.0 star property
9.0 out of 10, Wonderful, (383)
"I enjoyed my stay "
The price is ₩55,520
₩61,072 total
includes taxes & fees
Aug 20 - Aug 21
Hotel Milan
Riande Urban Hotel
2 bars/lounges, gastropub

Riande Urban Hotel

3.5 star property
8.8 out of 10, Excellent, (1034)
"Loved the staff and the hotel decor"
The price is ₩105,620
₩116,182 total
includes taxes & fees
Aug 20 - Aug 21
Riande Urban Hotel
Hotel Costa Inn
Balcony

Hotel Costa Inn

3.0 star property
7.0 out of 10, Good, (516)
"Place is good for a short time stay. Room service was good"
The price is ₩29,148
₩32,063 total
includes taxes & fees
Sep 15 - Sep 16
Hotel Costa Inn
Hotel Latino
Aerial view

Hotel Latino

3.0 star property
6.6 out of 10, (212)
"Fair for the price. Restaurant is great"
The price is ₩33,728
₩37,101 total
includes taxes & fees
Aug 20 - Aug 21
Hotel Latino
Aloft Panama
Exterior

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (837)
"Nice and convenient location."
The price is ₩162,396
₩178,636 total
includes taxes & fees
Aug 25 - Aug 26
Aloft Panama
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1033)
"Lovely hotel "
The price is ₩176,317
₩193,949 total
includes taxes & fees
Sep 12 - Sep 13
Megapolis Hotel Panamá
Best Western Plus Panama Zen Hotel
Outdoor pool, pool umbrellas, sun loungers

Best Western Plus Panama Zen Hotel

4.0 star property
9.0 out of 10, Wonderful, (911)
"This hotel is amazing"
The price is ₩115,548
₩127,103 total
includes taxes & fees
Aug 23 - Aug 24
Best Western Plus Panama Zen Hotel
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (501)
"Great location. "
The price is ₩211,184
₩232,302 total
includes taxes & fees
Aug 29 - Aug 30
Residence Inn by Marriott Panama City
Hotel California Panama
Outdoor pool

Hotel California Panama

3.0 star property
7.8 out of 10, Good, (85)
"Comfortable enough for a business stay. Clean and friendly place. "
The price is ₩53,299
₩58,629 total
includes taxes & fees
Aug 20 - Aug 21
Hotel California Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

See all hotels in Santa Clara

Top Santa Clara Hotel Reviews

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

10/10 Excellent
"It was good"
Imran Elleyaz 4-night trip
Posted 2 days ago
Dreams Playa Bonita Panama - All Inclusive

Frequently asked questions

What's the best place for a stay in Santa Clara?

Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Sheraton Grand Panama and Dreams Playa Bonita Panama - All Inclusive. See all available top hotels, or vacation rentals in Santa Clara.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.

What's the best place to stay near Culebra Cut?

Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.

What is staying in Santa Clara like?

Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1494 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.

What is there to see in Santa Clara?

A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.

What's the seasonal weather like in Santa Clara?

The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.