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Compare 44 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Santa Cruz hotels

Little Italy B&B

3.0 star property
9.4 out of 10, Exceptional, (49)
"Quiet and clean. Very nice stay!"
The price is ₩55,972
₩61,569 total
includes taxes & fees
Aug 23 - Aug 24
Little Italy B&B

Hotel Dos Rios

3.0 star property
8.6 out of 10, Excellent, (70)
"Excelente"
The price is ₩119,639
₩131,603 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Dos Rios

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

3.0 star property
8.2 out of 10, Very Good, (232)
"Great hotel"
The price is ₩141,048
₩155,153 total
includes taxes & fees
Sep 21 - Sep 22
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

Hotel Finca Lerida

3.0 star property
8.8 out of 10, Excellent, (182)
"The property is beautifully located on a coffee farm. The rooms are nice and bright. The restaurant is beautiful with outdoor seating with views of the mountain tops. The weather is prefect and you do not need an air conditioner. The staff were wonderful especially Luis. "
The price is ₩177,976
₩195,774 total
includes taxes & fees
Aug 25 - Aug 26
Hotel Finca Lerida

Los Quetzales Ecolodge & Spa

3.0 star property
8.6 out of 10, Excellent, (30)
"When I arrived to check in, I could not find anyone. Fortunately, a dog came and found me and me and led me to someone who checked me in. I reserved a room with a fireplace but was told that if I wanted a fireplace, I would have to pay extra. Room was very cramped and always cold. Water eventually ran hot but in a limited supply. Dining room options were limited but the food was good. Loved the balcony porch overlooking the garden. Very friendly dogs"
The price is ₩128,455
₩141,300 total
includes taxes & fees
Aug 23 - Aug 24
Los Quetzales Ecolodge & Spa

Linda Vista Cabins

3.0 star property
9.2 out of 10, Wonderful, (17)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
The price is ₩61,345
₩67,474 total
includes taxes & fees
Aug 25 - Aug 26
Linda Vista Cabins

Los Brezos Boutique Hotel

3.5 star property
9.4 out of 10, Exceptional, (22)
"Los Brezos is the best hotel in the area. The restaurant is amazing, the food at all times is delicious and high standard"
The price is ₩166,236
₩182,860 total
includes taxes & fees
Aug 23 - Aug 24
Los Brezos Boutique Hotel

Hostal Victoria Volcán Chiriquí S. A.

2.0 star property
8.8 out of 10, Excellent, (8)
"Hostal Victoria was a simple and down-to-earth Hostal. The entire staff were friendly, kind, and helpful. Good value for a budget place to stay. "
The price is ₩62,968
₩69,265 total
includes taxes & fees
Aug 25 - Aug 26
Hostal Victoria Volcán Chiriquí S. A.

Luxury Canyon Suites

2.0 star property
7.6 out of 10, Good, (4)
"Last minute booking over a busy weekend. Was really one of the only decent looking places available. Out of the way, although quite nice rooms and building I wouldn’t book there unless desperate for a room. Only a few staying and checking in late with a quite rude security guard seemed awkward. Anyway decent enough, adequate WiFi but on 35 m download and it’s all shared connection not per room as stated. I think if the place was full it would barely handle the load. All in all decent enough...
The price is ₩160,516
₩176,568 total
includes taxes & fees
Aug 23 - Aug 24
Luxury Canyon Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Head to Área Silvestre Protegida Lagunas de Volcán and Las Cavernas de Corredores—just two of the sights around Santa Cruz.

Top Santa Cruz Hotel Reviews

Frequently asked questions

Where is the best place to stay in Santa Cruz?

Located 12.3 mi (19.8 km) from the heart of Santa Cruz, Hotel Bambito By Faranda Boutique, a member of Radisson Individuals is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Hotel Finca Lerida and Los Quetzales Ecolodge & Spa. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best vacation home rentals in Santa Cruz?

Casa Little Italy: This vacation home rental outside of Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about picking new dates or cancelling your trip to Santa Cruz, go to https://www.expedia.com/service/.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 43 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Places to visit in the wider area include Área Silvestre Protegida Lagunas de Volcán, Las Cavernas de Corredores, and Arte Cruz Volcán. You'll also find Sitio Barriles Museum and Paradise Tropical Garden in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the weather like in Santa Cruz?

The hottest months are usually March and February with an average temp of 78°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa Cruz are October, November, August, and July, with each month seeing an average of 30 inches of rainfall.