Santa Cruz Island Vacations

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Find the Best Santa Cruz Island Vacation Packages

Santa Cruz Island Hotel Deals

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
The price is ₩231,971 per night from Mar 24 to Mar 25
₩231,971
₩231,971 total
Mar 24 - Mar 25
Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
The price is ₩215,162 per night from Mar 26 to Mar 27
₩215,162
₩215,162 total
Mar 26 - Mar 27
9.8/10 Exceptional! (120 reviews)
Very helpful staff. The water in the room was very convenient.

Reviewed on Mar 16, 2026

Maidith Galapagos Inn
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
8.8/10 Excellent! (193 reviews)
The staff was amazing, so attentive and kind!

Reviewed on Feb 25, 2026

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Hotel el descanso del Guia
See all 216 properties in Santa Cruz Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz Island

Hermosa playa, ubicada a 45min de Puerto Ayora en la isla Santa Cruz, Galápagos. Aquí se pueden observar flamingos, y disfrutar de zona de camping y alquiler de kayak.

El Garrapatero Beach

Why not spend a carefree afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.

El Garrapatero Beach

Frequently asked questions

Can I cancel my flight booking to Santa Cruz Island due to COVID-19?
Many airlines now provide more flexibility due to COVID-19. Our convenient Customer Service Portal will help answer most queries about which policies apply to your flight. It's also worth scanning over the terms and conditions of your chosen carrier — preferably before locking in your seat!
What's the best way to find cheap flights to Santa Cruz Island that have flexible change policies?
We know that travel arrangements can change from one day to the next, so choosing a flexible fare with Expedia is always a wise idea. Simply tick the "No change fee" box below the "Flexible change policies" filter. Your low-cost, flexible flight to Santa Cruz Island is only a few clicks away.
What are some of the general tips for travelers to Santa Cruz Island during the COVID-19 outbreak?
The COVID-19 pandemic has brought about big changes to the way we travel. If you're planning an escape to Santa Cruz Island, the following tips will help you navigate this new traveling reality:
  • Research if any travel restrictions apply to your origin and destination before booking your flight. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Wear a face mask even during airport screening. A TSA officer will require you to adjust your mask for identification purposes.
  • You're no longer required to hand your boarding pass (paper or electronic) directly to a TSA officer. Rather, you should position the pass on the reader and then hold it up to allow the agent to visually inspect it.
  • You are now allowed to take one container of hand sanitizer up to 12 oz (350 ml) in your carry-on luggage. This will need to be removed for X-ray scanning.
  • To minimize handling during the screening process, place items such as your phone, wallet and keys into your carry-on instead of the bins.
  • Separate any food you have for screening. Food items often trigger the alarm. Putting them in a clear plastic bag and into a bin reduces the need for a TSA agent to touch and inspect your belongings.

Which airlines fly to Santa Cruz Island?
LATAM Airlines Ecuador runs flights into or near Santa Cruz Island, including 60 that arrive at Seymour Airport (GPS) each month. Choose your vacation dates and then secure your seat early for the best price.
How can I find cheap tickets to Santa Cruz Island?
For the best deal to Santa Cruz Island, book well ahead of time. Also make use of Expedia's "flexible dates" link at the top of your search results. This will display prices for similar time frames. In the last seven days, was the lowest price for a flight to Santa Cruz Island.
How much is a flight to Santa Cruz Island?
If you were flying one way from (), you could've picked up a cheap ticket for in the last seven days. Round-trip flights to Santa Cruz Island ranged from only to during this same period.
What are the most popular airports to fly into in Santa Cruz Island?
Seymour Airport (GPS) is the main entryway for people traveling into and out of Santa Cruz Island. Approximately 95 flights a month touch down at this airport.
When is the cheapest time to fly to Santa Cruz Island?
Departing on a Tuesday, followed by a Monday, is generally the best way to bag the cheapest fare. Avoid the weekends if you can, because Saturday is typically the most expensive day of the week. Spend the cash you saved having a good time in Santa Cruz Island instead!
How much is a plane ticket to Santa Cruz Island?
In the last seven days, plane tickets to Santa Cruz Island fluctuated between and . Prices rise as your travel date nears, so grab a terrific deal today.
Which airlines with flights to Santa Cruz Island employ COVID-19 cleanliness policies?
Like most things, plane travel is looking very different nowadays. Airlines worldwide have adopted a range of measures, including social distancing, to slow the spread of COVID-19. Here are some of them:
  • LATAM Airlines Ecuador - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Avianca - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.