Santa Cruz Vacations & Trips

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    Save up to ₩1,660,000 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Santa Cruz Hotel Deals

Hotel Fiesta

Hotel Fiesta

Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
₩193,329
₩193,329 total
Aug 29 - Aug 30
9/10 Wonderful! (431 reviews)
"Clean, safe, very friendly staff. close to port and main shopping/dining. lovely pool, affordable drinks at bar and good breakfast."

Reviewed on Aug 22, 2026

Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
₩179,320
₩179,320 total
Aug 29 - Aug 30
10/10 Exceptional! (157 reviews)
"Pros: quiet location but still a close walk to town, excellent rotating breakfast options, warm pool for the kids to play in, very clean and comfortable, lots of character! Cons: none, we loved it all!"

Reviewed on Aug 13, 2026

Maidith Galapagos Inn
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

Barrio Punta Estrada Puerto Ayora Galapagos
₩761,647
₩839,929 total
Sep 24 - Sep 25
Finch Bay Galapagos Hotel
See all 221 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Handcraft your Santa Cruz vacation package from as little as . Pick from any combination of hotels, flights and rental cars to build the escape you've been dreaming about for ages. Be sure to add on a few experiences or activities!
How do I get a cheap travel package to Santa Cruz?
Our Santa Cruz vacation packages offer plenty of savings for the savvy globetrotter. For the best deal, simply bundle your hotel, flights and extras (such as activities) into an affordable package. But low prices are just the beginning of your next amazing adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotels throughout the world to pick from. Whatever your style, there's a vacation package that's perfect for you.
How far in advance should I book my Santa Cruz vacation?
To bag cheap prices, book ASAP. Airlines typically advertise flights, along with some of the lowest fares, nearly a year ahead of time. Hotels, car rental and experiences should also be booked well in advance to avoid disappointment. If you've decided on a last-minute getaway in Santa Cruz, there are always plenty of great bargains to be had on Expedia. Check them out now!
What does an Expedia Santa Cruz travel package include?
Rental cars, flights and hotels, or any combination of the three — the choice is yours. Whether you're exploring Santa Cruz with the whole family or adventuring solo, there's a package to suit your style and budget. Once you've made your booking, why not add on a couple of activities?
What should I know before booking a Santa Cruz travel package?
Get set to save with an Expedia travel package. Combine your airfares, rental cars and hotels and be rewarded with exciting discounts. Hotels aren't your only choice, though. We have oceanfront condos, creek-side mountain cabins and even glamping tents!
Can I choose my airline with a Santa Cruz Expedia vacation package?
Yes, and with more than 550 airlines to select from around the world, you've got lots of choice. Look through the available options and find out which airline suits your budget and needs.
If I'm not able to travel, can I cancel my Santa Cruz vacation package?
If your travel plans in Santa Cruz have changed, it's comforting to know that you can cancel your booking. If you made your booking less than 24 hours ago, you may be eligible to receive a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. To find out more, visit our Customer Service Portal.

Stay near popular Santa Cruz attractions

A beach with a small island in the distance.
Photo by Elizabeth Oates

Tortuga Bay Beach

9.6/10 (488 reviews)
If a restful vacation is part of your travel plans, Tortuga Bay Beach might be the perfect place to seek out during your trip to Bella Vista. While you're in the area, wander around the parks.
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A rocky shoreline with mangrove trees and calm ocean waters.
Photo by Luis Felipe

El Garrapatero Beach

9.2/10 (154 reviews)
Why not spend a carefree afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.
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Playa de los Alemanes

8.8/10 (262 reviews)
If a restful vacation is part of your travel plans, Playa de los Alemanes might be the perfect place to seek out during your trip to Puerto Ayora. While you're here, you can savor the top-notch restaurants.
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Malecon

9.2/10 (350 reviews)
You can find out about the history of Puerto Ayora with a visit to Malecon. Wander the waterfront and beaches in the area.
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Los Gemelos Sinkholes

9.2/10 (143 reviews)
Commune with nature and explore the great outdoors at Los Gemelos Sinkholes during your travels in Santa Rosa. Wander the waterfront and beaches in the area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.