Top 10 Hotels in Santa Fe, FL from ₩91,843 - Competitive Prices

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Our top choices for Santa Fe hotels

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.

A hotel lobby with a seating area featuring sofas and armchairs, a central coffee table, and a flat-screen TV mounted on the wall.

A hotel reception area with directional signs for elevators, floor 1, pool restrooms, and business center.

A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.

1. La Quinta by Wyndham Gainesville

Gainesville

Elizabeth

₩134,053

₩150,816 total

includes taxes & fees

Sep 30 - Oct 1

A spacious indoor dining area with multiple tables and chairs, large windows offering a view of palm trees and greenery outside.

A Holiday Inn Express & Suites hotel with a modern design, multiple floors, and a parking lot.

A lobby with a patterned carpet, two green armchairs, a white sofa, a small round table with a plant, and framed artwork on the wall.

A hotel room with a bed, a desk with a chair, a television, and a blue sofa.

2. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Alachua

Tobias

₩140,823

₩158,427 total

includes taxes & fees

Oct 5 - Oct 6

A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.

A modern hotel lobby with a reception desk, seating area with chairs and ottomans, a large artwork, and a corridor leading to other rooms.

A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.

A hotel room with a bed, a desk, a chair, a sofa, and a window.

3. Comfort Suites Gainesville near University

Gainesville

thomas

₩112,754

₩130,910 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.

A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.

A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.

4. Drury Inn & Suites Gainesville

Gainesville

Joan

₩142,164

₩159,935 total

includes taxes & fees

Oct 4 - Oct 5

A stone water feature with cascading water, surrounded by a brick wall and greenery.

A neatly arranged bedroom with a bed, bedside lamps, a TV, and a mirror.

A reception desk with a modern design, a ceiling fan, and a seating area with chairs and a table.

A spacious living area with a wooden floor, a blue sofa, a round coffee table, and a ceiling fan.

5. BlueGem Motel

High Springs

Wesley

₩126,226

₩142,004 total

includes taxes & fees

Oct 5 - Oct 6

A multi-story hotel with a central entrance, palm trees, and a clear sky.

A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.

A hotel room with a bed, a desk, a television, a sofa, and artwork on the wall.

A modern living room with a green sofa, a round coffee table, and a fireplace.

6. Country Inn & Suites by Radisson, Gainesville, FL

Gainesville

sherry

₩119,700

₩134,663 total

includes taxes & fees

Oct 7 - Oct 8

A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.

A building with a Coca-Cola vending machine, a window with a 'OPEN' sign, and a red awning.

A bathroom with a large mirror, a sink, and a towel rack.

A corner room with two checkered chairs, a small table, a framed picture on the wall, and a floor lamp.

7. Palms Garden Inn

Lake City

Igor

₩93,363

₩105,033 total

includes taxes & fees

Oct 4 - Oct 5

A modern interior with a staircase, a seating area, and a colorful abstract wall design.

A modern bar area with a marble countertop, bar stools, and pendant lighting.

A spacious lobby with modern furniture, large windows, and a colorful abstract wall.

A modern hotel lobby with a round table featuring two drinks, a sofa, and a colorful wall art piece.

8. Hyatt Place Gainesville Downtown

Downtown Gainesville

Claire

₩132,699

₩149,287 total

includes taxes & fees

Oct 5 - Oct 6

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

A hotel room with two beds, a desk, a chair, a TV, and a couch.

A reception desk with a "Welcome to the Sun Shine State" sign, a "Treats" sign, and a minibar area with a "Hilton" sign.

9. Hampton Inn & Suites Alachua I-75

Alachua

Pamela

₩143,234

₩161,138 total

includes taxes & fees

Oct 11 - Oct 12

A large, multi-story hotel with a central courtyard, palm trees, and an American flag.

A spacious lobby with a large painting, a fireplace, a piano, and multiple seating areas.

A spacious dining area with multiple tables and chairs, a kitchen area with a coffee station, and large windows allowing natural light.

A bar area with wooden chairs, a bar counter, and a television mounted on the wall.

10. Best Western Gateway Grand

Gainesville

Jason

₩114,500

₩128,813 total

includes taxes & fees

Oct 6 - Oct 7

A modern hotel lobby with a curved ceiling, a central seating area with a sofa and ottoman, a bar area, and a dining space with chairs and tables.

A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and large windows offering views of the outside.

A modern hotel lobby with a breakfast bar, seating area, and a large window.

A hotel entrance with a sign reading "Springhill Suites by Marriott" and a modern building in the background.

11. SpringHill Suites by Marriott Gainesville

Gainesville

Robert

₩115,857

₩130,339 total

includes taxes & fees

Oct 4 - Oct 5

A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.

A hotel hallway with carpeted floors, doors on both sides, and overhead lighting.

A hotel room with a living area, kitchenette, and a large mirror.

A hotel room with a kitchenette, a bed, a desk with a chair, and a bathroom.

12. Hampton Inn Gainesville

Gainesville

Charles

₩121,427

₩136,606 total

includes taxes & fees

Oct 6 - Oct 7

A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.

A bedroom with a bed, a chair, a dresser, a ceiling fan, a window with blinds, and a wall-mounted air conditioner.

A stone outdoor seating area with a table and benches, a trash bin, and a building in the background.

A row of motel buildings with a fire hydrant and trees in front.

13. High Springs Country Inn

High Springs

Luis

₩88,353

₩99,397 total

includes taxes & fees

Oct 8 - Oct 9

A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.

A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

An outdoor patio with tables and chairs, a stone wall, and a view of a street with trees and buildings.

A Holiday Inn Express building with a modern design, featuring multiple windows and a flat roof.

14. Holiday Inn Express Starke by IHG

Starke

Judy

₩149,441

₩165,880 total

includes taxes & fees

Oct 4 - Oct 5

A hotel entrance with a covered driveway, flag poles, and a well-lit facade.

A modern dining area with a wooden table, four chairs, and a fireplace.

A spacious lobby with a reception desk, seating areas, and potted plants.

An outdoor seating area with tables and chairs, surrounded by greenery and a building with large windows.

15. Hilton Garden Inn Gainesville

Gainesville

jose

₩126,753

₩142,597 total

includes taxes & fees

Oct 1 - Oct 2

A modern bar area with a long counter, green bar stools, and a television displaying a golf game.

A modern hotel room with a large bed, a desk, a chair, and a TV mounted on the wall.

A Fairfield Inn & Suites Marriott hotel with a modern entrance, multiple floors, and a parking lot.

A modern living room with a fireplace, comfortable seating, and a large TV.

16. Fairfield Inn & Suites by Marriott Gainesville I-75

Gainesville

Robert

₩161,134

₩181,276 total

includes taxes & fees

Oct 11 - Oct 12

A modern building with a curved facade, a landscaped pathway, and a body of water in the foreground.

A modern living room with a flat-screen TV, wooden shelving, a small table, a sofa, and a large window offering a city view.

An outdoor seating area with tables and chairs, a water feature, and modern buildings in the background.

A bartender pouring a drink into a glass.

17. Hotel Eleo at the University of Florida

Gainesville

Diane

₩218,747

₩246,090 total

includes taxes & fees

Oct 1 - Oct 2

A swimming pool with a 5 ft 8 in depth marker, surrounded by lounge chairs and red umbrellas, with a fence and trees in the background.

A two-story motel with a covered entrance, a parking lot, and a clear sky.

A workspace with two chairs, a desk, a computer monitor, and a wall-mounted sign reading 'BUSINESS CENTER'.

A modern hotel lobby with a reception desk, seating area, and a wall-mounted television.

18. Clarion Pointe Alachua - Gainesville Area

Alachua

María Teresa

₩81,744

₩98,755 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.

A hotel room with two beige armchairs, a small side table, a glass display cabinet with sports memorabilia, a mounted flat-screen TV, and a door with a wooden frame.

Outdoor lounge chairs with metal frames and fabric seats, arranged in rows.

A breakfast bar with a juice dispenser, cereal boxes, and fruit bowls.

19. Sleep Inn & Suites University/Shands

Gainesville

prakasa Babu

₩102,774

₩123,264 total

includes taxes & fees

Oct 19 - Oct 20

A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

A hotel room with a bed, a desk with a chair, a television, a mirror, and a wardrobe.

A reception desk with a sign reading "Quality by Choice Hotels," surrounded by various reptile decorations.

A spacious lobby with a dining area, a kitchen, and a large window providing a view of the outdoors.

20. Quality Inn Alachua - Gainesville Area

Alachua

Deborah

₩103,236

₩116,141 total

includes taxes & fees

Oct 19 - Oct 20

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Top Santa Fe Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent

"Nice clean hotel"

Hilton University of Florida Conference Center Gainesville

10/10 Excellent

"So many options for entertainment and dining without even leaving the hotel."

HOM Hotel Gainesville, SureStay Collection by Best Western

10/10 Excellent

"Great hotel with nice staff!"

DoubleTree by Hilton Gainesville

8/10 Good

"Rooms are fine - very limited counter space in the bathroom"

Drury Inn & Suites Gainesville

10/10 Excellent

"Great location & staff!"

Red Roof Inn PLUS+ Gainesville

8/10 Good

"Everything was great!"

Comfort Suites Gainesville near University

8/10 Good

"The hotel is nice"

Hotel Indigo Gainesville-Celebration Pointe by IHG

8/10 Good

"H"

Best Western Gateway Grand

8/10 Good

"Nice staff, clean hotel, good location and good breakfast"

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL

₩81,638

₩91,843 total

Oct 4 - Oct 5

includes taxes & fees

7.4/10 Good! (1,333 reviews)

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL

₩97,832

₩110,059 total

Oct 5 - Oct 6

includes taxes & fees

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL

₩98,089

₩110,350 total

Oct 5 - Oct 6

includes taxes & fees

8.6/10 Excellent! (2,148 reviews)

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL

₩102,774

₩123,264 total

Oct 19 - Oct 20

includes taxes & fees

8.8/10 Excellent! (1,304 reviews)

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL

₩103,410

₩123,953 total

Oct 18 - Oct 19

includes taxes & fees

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL

₩112,754

₩130,910 total

Oct 18 - Oct 19

includes taxes & fees

9.2/10 Wonderful! (1,505 reviews)

Frequently asked questions

What's the best place for a stay in Santa Fe?

Located 18.6 mi (30 km) from the heart of Santa Fe, Drury Inn & Suites Gainesville is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Sleep Inn & Suites University/Shands and Country Inn & Suites by Radisson, Gainesville, FL. See all available top hotels, or vacation rentals in Santa Fe.

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

Where can I learn more about changing or cancelling my trip to Santa Fe?

To access more information about picking new dates or cancelling your trip to Santa Fe, go to https://www.expedia.com/service/.

What is staying in Santa Fe like?

Travelers to Santa Fe will find plenty to explore and enjoy. There are 796 hotels and other accommodations in the surrounding area. Find out more about Santa Fe.

What are the top places to visit in Santa Fe?

Places to visit in the wider area include Turkey Creek Golf Course, O'Leno State Park, and San Felasco Hammock Preserve State Park. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Check out what more to see and do in Expedia's Santa Fe guide.

What's the seasonal weather like in Santa Fe?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 59°F. The rainiest months in Santa Fe are August, June, July, and September, with each month seeing an average of 7 inches of rainfall.

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Find hotels in Santa Fe, FL from ₩91,843

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Fe

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Fe hotels

1. La Quinta by Wyndham Gainesville

2. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3. Comfort Suites Gainesville near University

4. Drury Inn & Suites Gainesville

5. BlueGem Motel

6. Country Inn & Suites by Radisson, Gainesville, FL

7. Palms Garden Inn

8. Hyatt Place Gainesville Downtown

9. Hampton Inn & Suites Alachua I-75

10. Best Western Gateway Grand

11. SpringHill Suites by Marriott Gainesville

12. Hampton Inn Gainesville

13. High Springs Country Inn

14. Holiday Inn Express Starke by IHG

15. Hilton Garden Inn Gainesville

16. Fairfield Inn & Suites by Marriott Gainesville I-75

17. Hotel Eleo at the University of Florida

18. Clarion Pointe Alachua - Gainesville Area

19. Sleep Inn & Suites University/Shands

20. Quality Inn Alachua - Gainesville Area

Top Santa Fe Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Hilton University of Florida Conference Center Gainesville

HOM Hotel Gainesville, SureStay Collection by Best Western

DoubleTree by Hilton Gainesville

Drury Inn & Suites Gainesville

Red Roof Inn PLUS+ Gainesville

Comfort Suites Gainesville near University

Hotel Indigo Gainesville-Celebration Pointe by IHG

Best Western Gateway Grand

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

Days Inn by Wyndham Gainesville University I-75

HOM Hotel Gainesville, SureStay Collection by Best Western

Sleep Inn & Suites University/Shands

Comfort Inn Gainesville - University Area

Comfort Suites Gainesville near University

Frequently asked questions

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