Top 10 Hotels in Santa Fe, FL from ₩90,668 - Competitive Prices

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Our top choices for Santa Fe hotels

A hotel with a covered entrance, stone facade, and blue lighting accents.

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Alachua

Austin

₩150,284 total

includes taxes & fees

Dec 14 - Dec 15

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

2. Hampton Inn & Suites Alachua I-75

Alachua

Pamela

₩170,877 total

includes taxes & fees

Nov 29 - Nov 30

A large, multi-story hotel with a central courtyard, palm trees, and an American flag.

3. Best Western Gateway Grand

Gainesville

Jvotric

₩126,861 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.

4. La Quinta by Wyndham Gainesville

Gainesville

Megan

₩145,824 total

includes taxes & fees

Nov 15 - Nov 16

A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

5. Quality Inn Alachua - Gainesville Area

Alachua

faye

₩108,378 total

includes taxes & fees

Nov 22 - Nov 23

A multi-story hotel with a central entrance, palm trees, and a clear sky.

6. Country Inn & Suites by Radisson, Gainesville, FL

Gainesville

Jeff

₩132,623 total

includes taxes & fees

Nov 22 - Nov 23

A modern interior with a staircase, a seating area, and a colorful abstract wall design.

7. Hyatt Place Gainesville Downtown

Downtown Gainesville

Misak

₩155,274 total

includes taxes & fees

Nov 22 - Nov 23

A fire pit area surrounded by stone tiles, with a metal fence in the background.

8. Comfort Suites Gainesville near University

Gainesville

Samantha

₩124,835 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with a bed, bedside tables, a TV, a window with curtains, and a wall with artwork.

9. Sleep Inn & Suites University/Shands

Gainesville

Gertlenith

₩120,994 total

includes taxes & fees

Dec 4 - Dec 5

A modern bar area with a long counter, green bar stools, and a television displaying a golf game.

10. Fairfield Inn & Suites by Marriott Gainesville I-75

Gainesville

Robert

₩178,528 total

includes taxes & fees

Nov 15 - Nov 16

A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.

11. Holiday Inn Express Starke by IHG

Starke

Georgia

₩149,763 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel room with a large bed, a flat-screen TV, a desk, and a mural of a landscape.

12. Clarion Pointe Alachua - Gainesville Area

Alachua

Debra

₩108,669 total

includes taxes & fees

Dec 6 - Dec 7

A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.

13. Best Western Waldo Inn and Suites

Waldo

Sarah

₩126,230 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

14. Drury Inn & Suites Gainesville

Gainesville

Michael

₩157,509 total

includes taxes & fees

Nov 26 - Nov 27

An outdoor patio with wicker furniture, stone walls, and a barbecue grill.

15. TownePlace Suites by Marriott Gainesville Northwest

Gainesville

Jell

₩157,104 total

includes taxes & fees

Nov 16 - Nov 17

An outdoor seating area with a fire feature, chairs, and tables.

16. Hotel Indigo Gainesville-Celebration Pointe by IHG

Gainesville

Lorraine

₩153,052 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and large windows offering views of the outside.

17. SpringHill Suites by Marriott Gainesville

Gainesville

Hoang

₩127,941 total

includes taxes & fees

Nov 18 - Nov 19

18. HOM Hotel Gainesville, SureStay Collection by Best Western

Gainesville

Jenna

₩108,678 total

includes taxes & fees

Nov 22 - Nov 23

A spacious hotel lobby with a curved sofa, a patterned carpet, and a large window with sheer curtains.

19. Hilton University of Florida Conference Center Gainesville

Gainesville

Yuleivy

₩158,696 total

includes taxes & fees

Nov 22 - Nov 23

A cabin with a cozy interior, a dining area, and a view of the forest.

20. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

High Springs

Katie

₩290,951 total

includes taxes & fees

Dec 14 - Dec 15

View all properties

Top Santa Fe Hotel Reviews

Hampton Inn & Suites Alachua I-75

Alachua

10/10 Excellent

Jose

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

High Springs

10/10 Excellent

Alexander

La Quinta by Wyndham Gainesville

Gainesville

10/10 Excellent

Alan

Drury Inn & Suites Gainesville

Gainesville

10/10 Excellent

Jennifer

A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.

Vista Verde Farm Retreat

Lake City

10/10 Excellent

Steven

Best Western Gateway Grand

Gainesville

10/10 Excellent

jennifer Louise

Hotel Indigo Gainesville-Celebration Pointe by IHG

Gainesville

10/10 Excellent

Katrina

Sleep Inn & Suites University/Shands

Gainesville

10/10 Excellent

Lisa

Fairfield Inn & Suites by Marriott Gainesville I-75

Gainesville

10/10 Excellent

Marita

Country Inn & Suites by Radisson, Gainesville, FL

Gainesville

10/10 Excellent

Georgette

Best Western Waldo Inn and Suites

Waldo

10/10 Excellent

Parker

Comfort Suites Gainesville near University

Gainesville

10/10 Excellent

My daughter & I stay here frequently as it’s conveniently located near the medical facility UF Health. They apparently put great effort in keeping the facility clean. A lot of fact that it’s just shy of all the hustle and bustle of Gainesville, but within minutes of the University and the Hospital, the staff has accommodated me when I’ve asked for special needs, and I will always return to this this hotel.

Elizabeth

A large, two-story house with a porch, multiple windows, and a chimney.

Sweetwater Branch Inn

Gainesville

10/10 Excellent

I had a mini vacation here between conferences at the University of Florida. I had a delightful room, wonderful facilities, gardens, saltwater pool, and the cat Butterscotch was a wonderful friend as I had a lovely evening in a rocker on the porch with a bit of wine and a book. I highly recommend the massage therapist option. She was wonderful and set up and collapse was not intrusive in my room.

Carol

Frequently Asked Questions

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled before the hotel’s cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

Where can I learn more about changing or cancelling my trip to Santa Fe?

To access more information about picking new dates or cancelling your trip to Santa Fe, go to https://www.expedia.com/service/.

Find hotels in Santa Fe, FL from ₩90,668

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Go beyond your typical stay in Santa Fe

Check prices for these dates

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Our top choices for Santa Fe hotels

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

2. Hampton Inn & Suites Alachua I-75

3. Best Western Gateway Grand

4. La Quinta by Wyndham Gainesville

5. Quality Inn Alachua - Gainesville Area

6. Country Inn & Suites by Radisson, Gainesville, FL

7. Hyatt Place Gainesville Downtown

8. Comfort Suites Gainesville near University

9. Sleep Inn & Suites University/Shands

10. Fairfield Inn & Suites by Marriott Gainesville I-75

11. Holiday Inn Express Starke by IHG

12. Clarion Pointe Alachua - Gainesville Area

13. Best Western Waldo Inn and Suites

14. Drury Inn & Suites Gainesville

15. TownePlace Suites by Marriott Gainesville Northwest

16. Hotel Indigo Gainesville-Celebration Pointe by IHG

17. SpringHill Suites by Marriott Gainesville

18. HOM Hotel Gainesville, SureStay Collection by Best Western

19. Hilton University of Florida Conference Center Gainesville

20. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Top Santa Fe Hotel Reviews

Hampton Inn & Suites Alachua I-75

10/10 Excellent

Frequently Asked Questions

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Where can I learn more about changing or cancelling my trip to Santa Fe?