A tropical island with a beach, clear turquoise waters, and lush greenery.

Find hotels in Santa Isabel from ₩192,141

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Check prices for these dates

Tonight
Oct 8 - Oct 9
Tomorrow
Oct 9 - Oct 10
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

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Our top choices for Santa Isabel hotels

1. Cabins on paradise San Blas island

Cabins on paradise San Blas island
Narganá
₩360,190
₩396,209 total
includes taxes & fees
Oct 16 - Oct 17
Cabins on paradise San Blas island

2. Cabins in Chichime Island

Cabins in Chichime Island
Narganá
France
Anonymous traveler
₩214,428
₩235,871 total
includes taxes & fees
Oct 9 - Oct 10
Cabins in Chichime Island

3. Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island
Narganá
United States
Ryan
₩251,772
₩276,949 total
includes taxes & fees
Oct 9 - Oct 10
Private Ocean-Front Cabin with private bathroom on San Blas Island

4. Trips Guna Yala

Trips Guna Yala
Narganá
₩124,682
₩306,471 total
includes taxes & fees
Oct 18 - Oct 19
Trips Guna Yala

5. Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
Narganá
₩2,737,844
₩3,011,628 total
includes taxes & fees
Oct 9 - Oct 10
Cocoloco - Catamaran Lagoon 52F SAN BLAS

6. Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom
Narganá
₩174,674
₩192,141 total
includes taxes & fees
Nov 1 - Nov 2
Private wood Cabins on San Blas island - private bathroom
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Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkeling. Hike through lush rainforest trails to spot colorful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

See all hotels in Santa Isabel
A tropical island with a beach, clear turquoise waters, and lush greenery.

Top Santa Isabel Hotel Reviews

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
Ryan 4-night trip
Posted 8 months ago
Private Ocean-Front Cabin with private bathroom on San Blas Island

More cheap stays in Santa Isabel

Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom

Wailidup Island Narganá Guna Yala
₩174,674
₩192,141 total
Nov 1 - Nov 2
includes taxes & fees
Private wood Cabins on San Blas island - private bathroom
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala
₩251,772
₩276,949 total
Oct 9 - Oct 10
includes taxes & fees
10/10 Exceptional! (1 review)
Private Ocean-Front Cabin with private bathroom on San Blas Island
Trips Guna Yala

Trips Guna Yala

Urgandi, Mamardub Narganá Guna Yala
₩124,682
₩306,471 total
Oct 18 - Oct 19
includes taxes & fees
Trips Guna Yala
Cabins on paradise San Blas island

Cabins on paradise San Blas island

9.587566, -78.879820 Narganá San Blas
₩360,190
₩396,209 total
Oct 16 - Oct 17
includes taxes & fees
Cabins on paradise San Blas island
 Paradise Over the Water Cabins in San Blas

Paradise Over the Water Cabins in San Blas

G4V2 48 Narganá Guna Yala
Get rates
6/10 (1 review)
Paradise Over the Water Cabins in San Blas
Hotel El Porvenir

Hotel El Porvenir

Isla Porvenir Narganá Guna Yala
Get ratesHotel El Porvenir

Frequently asked questions

What's the best place to stay in Santa Isabel?
Located 21.7 mi (34.8 km) from the heart of Santa Isabel, Private Ocean-Front Cabin with private bathroom on San Blas Island is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Cocoloco - Catamaran Lagoon 52F SAN BLAS and Private wood Cabins on San Blas island - private bathroom. See all available top hotels, or vacation rentals in Santa Isabel.
What are some of the best vacation home rentals that Santa Isabel has to offer?
Casa frente al mar - turtle cay marina: This vacation home rental outside Santa Isabel is located in the suburbs and has a terrace, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a stovetop, a microwave, and kitchenware. See all vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
Where can I learn more about changing or cancelling my trip to Santa Isabel?
For additional details about rescheduling or cancelling your trip to Santa Isabel, go to https://www.expedia.com/service/.
What's the best place to stay near Tocumen International Airport (PTY)?
Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer including its parks. There are 38 hotels and other accommodations in the surrounding area. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
Places to visit in the wider area include Chagres National Park and Porvenir Museum. Check out what more to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather like in Santa Isabel?
The hottest months are usually June and September with an average temp of 80°F, while the coldest months are February and March with an average of 78°F. The rainiest months in Santa Isabel are October, August, July, and November, with each month seeing an average of 12 inches of rainfall.