Santa Regina Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩234,741 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Regina

Find the best Santa Regina areas and neighborhoods for the activities you enjoy most. Learn more about Santa Regina
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Rio Pequeno

2 out of top 10 points of interest in this area

If you're spending some time in Rio Pequeno, Maria's Camboriú and Casa de Madrinha are top sights worth seeing.

Find hotels in Rio Pequeno

Santa Regina Hotel Deals

Mercure Itajaí Navegantes

Mercure Itajaí Navegantes

3.5 out of 5
Rua PEDRO FERREIRA, 363 Itajai
Fully refundableReserve now, pay when you stay
The price is ₩90,786 per night from Apr 5 to Apr 6
₩90,786
₩92,602 total
Apr 5 - Apr 6
includes taxes & fees
9.4/10 Exceptional! (624 reviews)
We always stay at mercury in Itajaí SC Brazil . Highly recommend. Super clean breakfast and dinner couldn’t be better .

Reviewed on Mar 14, 2026

Mercure Itajaí Navegantes
Nobile Grand Itapema

Nobile Grand Itapema

4 out of 5
R. 321 Itapema SC
Fully refundableReserve now, pay when you stay
The price is ₩127,180 per night from Apr 24 to Apr 25
₩127,180
₩130,996 total
Apr 24 - Apr 25
includes taxes & fees
Nobile Grand Itapema
Fazzenda Park Resort

Fazzenda Park Resort

4 out of 5
Rua Joao Mathias Zimermann 2299 Gaspar SC
Get rates
Fazzenda Park Resort
See all 2,410 properties in Santa Regina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Regina vacation package cost?
We make it easy to see the world, with Santa Regina vacation packages starting from as low as . You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your travel itinerary?
How do I get a cheap travel package to Santa Regina?
Crafting your own Santa Regina vacation package with Expedia is a simple way to save. We have access to more than 550 air carriers and 1,000,000 properties globally. With such a wonderful range to select from, you'll have no issues creating your dream escape.
Where should I stay in Santa Regina?
Stay where the action happens. Many visitors favor hotels in the vicinity of top sights, such as Raimundo Goncalez Malta Nature Park, Acervo Ayrton Senna and Camboriu Football Stadium.
How far in advance should I book my Santa Regina vacation?
To bag cheap prices, book early. Air carriers usually release flight tickets, along with some of the lowest fares, up to a year prior to departure. Hotels, activities and car rental should also be booked well in advance to avoid disappointment. If you've decided on a last-minute getaway in Santa Regina, there are always plenty of great bargains to be had on Expedia. Check them out now!
What does an Expedia Santa Regina travel package include?
Hotels, flights and a cool car for all your road trip adventures. Simply choose your preferred bundle and get access to great discounts. Once you've made your booking, add on some experiences and tours and watch your savings stack up. When it comes to crafting your Santa Regina getaway, you're in charge!
What should I know before booking a Santa Regina travel package?
Discover deals to match your budget with an Expedia package. Flights, hotels, rental cars — we've got everything you need to plan your getaway. You'll save a tidy sum just for combining your bookings. Whether you're embarking on a ski adventure or sipping cocktails on a beach, your perfect getaway is only a few clicks away.
Can I choose my airline with a Santa Regina Expedia vacation package?
Yes, definitely. Expedia has over 550 airline partners to select from all over the world. With such a big range of choice, finding the perfect carrier to whisk you off to Santa Regina will be a snap.
If I'm not able to travel, can I cancel my Santa Regina vacation package?
Because we know life can throw you a few curveballs, the answer is yes. For more information, check out our Customer Service Portal. But generally speaking, if you've booked your Santa Regina vacation package in the last 24 hours, you may be able to cancel or change it without penalty. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.