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Find Pet-friendly Hotels in Sikeston, MO

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Check availability on Sikeston Pet-friendly Hotels

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Sikeston pet-friendly hotels

Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is ₩129,735
₩149,154 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Drury Inn & Suites Sikeston, MO
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1009)
"Great place and staff, very accommodating!"
United States
Megan
The price is ₩129,735
₩146,343 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1004)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ₩108,975
₩124,203 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Plus Sikeston
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (724)
"Room was good as usual. This is 4th stay over past 5 years. Only issue I had on this stay was the orange juice from breakfast options. "
United States
Todd
The price is ₩79,998
₩91,178 total
includes taxes & fees
Dec 30 - Dec 31
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is ₩100,902
₩113,834 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Pear Tree Inn Cape Girardeau West
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (454)
"Very clean and super friendly staff!"
United States
Katherine
The price is ₩140,677
₩159,281 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn Sikeston
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"Awesome stay!"
United States
Breckin
The price is ₩129,735
₩146,343 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Inn & Suites Cape Girardeau
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1006)
"Very clean, very friendly! We will be staying again. "
United States
Beth
The price is ₩108,110
₩124,285 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Pear Tree Inn Sikeston
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (283)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is ₩127,443
₩145,253 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn & Suites Sikeston I-55
Breakfast, lunch, dinner served; American cuisine
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (390)
"Clean room, friendly staff and quiet stay."
United States
Margo
The price is ₩111,368
₩125,053 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Travelodge by Wyndham Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sikeston Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Awesome stay!"
Breckin 1-night trip
Posted 23 hours ago
Drury Inn & Suites Cape Girardeau

Frequently asked questions

What's the best pet-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Hampton Inn Sikeston and Pear Tree Inn Sikeston.
How many hotels that welcome pets will I find in Sikeston?
Enjoy traveling with your furry pal at one of Expedia's 10 Sikeston hotels that allow pets.
What's the best time of year to travel to Sikeston with my pet?
When you're traveling with pets, keeping track of the weather can make the trip safe and fun for everyone. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What is there to see and do with your pet in Sikeston?
Known for its riverfront, Sikeston has lots to offer visitors including its university life and museums. See the local sights and visit City of Miner Convention Center and Sikeston Depot Museum. While you're there, make sure you don't miss Central Park.