Consider a stay at Best Western Plus Sikeston I-55 and take advantage of free full breakfast, a grocery/convenience store, and shopping on site. In addition to laundry facilities and a gym, guests can connect to free WiFi in public areas, with speed of 25+ Mbps.
Sikeston is home to Best Western Plus Sikeston I-55. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights. Visit our Sikeston travel guide
120 S Interstate Drive, Sikeston, MO, 63801
What's nearby
Southeast Missouri State University
30 min drive - 60.2 km
City of Miner Convention Center
16 min walk - 1.4 km
Sikeston Depot Museum
5 min drive - 7.3 km
Riverfront Park
29 min drive - 59.1 km
Century Casino & Hotel Cape Girardeau
31 min drive - 60.8 km
Getting around
Cairo, IL (CIR-Cairo Regional)
30 min drive
Restaurants
Lambert's Cafe
3 min drive
Taco Bell
6 min drive
Buffalo Wild Wings
6 min drive
The 110 Grill
3 min drive
Pizza Inn
3 min drive
About this property
Best Western Plus Sikeston I-55
Property highlights
Take advantage of free full breakfast, a grocery/convenience store, and shopping on site at Best Western Plus Sikeston I-55. Stay connected with free WiFi in public areas, with speed of 25+ Mbps, and guests can find other amenities such as laundry facilities and a gym.
Additional perks include:
An indoor pool
Free self parking
Express check-out, a computer station, and an elevator
Smoke-free premises, a 24-hour front desk, and a water dispenser
Guest reviews give top marks for the helpful staff and location
Room features
All 55 rooms offer comforts such as laptop-friendly workspaces and air conditioning, as well as perks like high-speed internet.
Extra conveniences in all rooms include:
Rollaway/extra beds (surcharge) and free cribs/infant beds
Bathrooms with tubs or showers and free toiletries
How much does it cost to stay at Best Western Plus Sikeston I-55?
As of Nov 11, 2026, prices found for a 1-night stay for 2 adults at Best Western Plus Sikeston I-55 on Dec 7, 2026 start from ₩97,607, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Best Western Plus Sikeston I-55 pet-friendly?
Yes, pets are allowed at this property. There's a fee of USD 25.00 per pet, per night. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much is parking?
Self parking is free at this property.
What time is check-in at Best Western Plus Sikeston I-55?
Check-in start time: 3 PM; Check-in end time: anytime.
What time is check-out at Best Western Plus Sikeston I-55?
Check-out is at 11 AM.
Where is Best Western Plus Sikeston I-55 located?
Situated in Sikeston, this hotel is 0.7 mi (1.2 km) from City of Miner Convention Center and within 6 mi (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.
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Reviews
Best Western Plus Sikeston I-55 Reviews
8.4
Very Good
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
We knew we were going to do a quick stop and stay overnight and
this was perfect for that. We didn't use the pool or any amenities. Room
was clean, staff was very friendly and breakfast was good. We at at Lambert's
which was good and a lot of fun and I would not hesitate to stay here again.
Stayed 1 night in Oct 2026
Verified review
6/10 Okay
Ricky
Sep 11, 2026
Liked: Cleanliness, staff & service
Hotel staff were nice and helpful. Breakfast was decent and everything was available and everything was in working order.
The room was big enough for three adults. The pool was nice and relaxing. My husband especially liked the breakfast as they served biscuits and gravy. We would definitely book this hotel again if the need arises.
nice and covenant have stay here a few times, staff always has a smile.
Stayed 1 night in Mar 2026
Verified review
6/10 Okay
Deborah
Oct 26, 2026
Liked: Staff & service
Disliked: Amenities
It looked better in the pictures. I would not stay there again until they renovate the place. The breakfast was not great coffee was lukewarm. No charging outlets in the rooms at all. It was like going back to the 80’s . The staff was very nice though.
Everything was well but the actual property was a little winding getting there (but i wasarriving at night) and there is not another business next to it, just a small lake, If you like that. Overall clean, nice and quiet. Nice breakfast room!
Room was clean, the bathroom had a good vent and nice lighting which we've had a problem with with other hotels. Very satisfied with our stay and breakfast was gold.