South America Vacations & Trips

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Top destinations in South America

A plaza with a large building featuring a dome and spires, surrounded by trees and people.
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Medellín

Medellín

South America Hotel Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
The price is ₩125,062 per night from Aug 6 to Aug 7
₩125,062
₩129,380 total
Aug 6 - Aug 7
7.8/10 Good! (423 reviews)
"I didnt like the poor breakfast"

Reviewed on Jul 25, 2026

Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
The price is ₩163,221 per night from Aug 15 to Aug 16
₩163,221
₩167,539 total
Aug 15 - Aug 16
Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
6.6/10 (301 reviews)
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on Mar 6, 2018

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Concorde Hotel
See all 126,926 properties in South America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

If I'm not able to travel, can I cancel my South America vacation package?
It's good to know that you can cancel your South America booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
When is the best time of year to visit South America?
If keeping expenses to a minimum is a priority, is the best time to escape to South America. is usually the priciest month, so you'll need a bigger travel budget if you visit then. are the peak season months and when this destination is often at its most exciting. Clear space in your calendar for if you'd prefer a quieter escape.
How far in advance should I book my South America vacation?
It's hard to pick the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available to compare up to a year in advance. If you're booking at the last minute, don't despair. Cheap prices appear from time to time just weeks before departure dates.
What should I know before booking a South America travel package?
A Expedia travel package can be customized for your budget and is a great way to stretch your dollars further. How little or much you include is your call. Hotels, rental cars and flights — decide on a combination that works with your plans.
Can I travel to South America right now?
For all the information you need about visiting South America, head to our Covid-19 Travel Advisor. Covering travel restrictions, quarantine policies and more, Expedia will help make your trip planning as stress-free as possible.

Stay near popular South America attractions

A city street with modern buildings, a bridge, and a clear sky.

Paulista Avenue

9.0/10 (2,555 reviews)
See the financial and cultural heart of one of South America’s busiest cities before unwinding in a bar full of local business people at the end of the day.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.