The Best Hotels Closest to South Texas Medical Center in San Antonio for 2026

A modern medical building with reflective glass windows and a clear sky.

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Our top choices for South Texas Medical Center hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

A hotel room with two beds, a TV, a desk with a lamp, and a dresser.

A spacious indoor area with a long wooden reception desk, multiple seating arrangements, and large windows providing natural light.

An indoor swimming pool with multiple lanes, safety signs, and a view of the outside through large windows.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District, 2.9 km from South Texas Medical Center

Melissa

₩120,731

₩142,716 total

includes taxes & fees

Sep 21 - Sep 22

A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

A reception area with a wooden reception desk, a 'Corner Market' sign, and a refrigerator stocked with beverages.

A modern cafe with wooden furniture, white tables, and a brick wall.

A Fairfield by Marriott Inn & Suites building with a modern design, featuring a prominent entrance with a covered walkway and a parking lot in front.

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District, 1 km from South Texas Medical Center

Jennifer

₩128,364

₩149,866 total

includes taxes & fees

Sep 21 - Sep 22

A self-service snack and drink vending area with multiple shelves stocked with various products.

A hotel lobby with a reception desk, seating area, and a chandelier.

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

A hotel with a red-roofed entrance, multiple floors, and a visible flag.

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District, 2.4 km from South Texas Medical Center

Angela

₩119,134

₩140,814 total

includes taxes & fees

Sep 17 - Sep 18

A hotel pool area with lounge chairs and a building with large windows in the background.

A large conference room with a high ceiling, large windows, and a patterned carpet.

A large banquet hall with round tables, chairs, and chandeliers.

4. The Westin San Antonio North

3.2 km from South Texas Medical Center

Noemi

₩125,440

₩150,388 total

includes taxes & fees

Sep 24 - Sep 25

A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

A hotel entrance with an Atria Inn & Suites sign, a Classic Collins store, and a clear sky.

A hotel room with a sofa, a desk, a chair, a bed, and a mirror.

A hotel room with a bed, two bedside tables with lamps, a desk with a telephone, a mirror, and a door leading to another room.

5. Atria Inn & Suites

Medical Center District, 2.2 km from South Texas Medical Center

José

₩77,752

₩90,775 total

includes taxes & fees

Sep 18 - Sep 19

A modern kitchen with a large window, wooden counter, and two bar stools.

A compact kitchenette with a built-in microwave, a black refrigerator, and a wooden countertop.

A Park Inn hotel with a brick facade, multiple parking spaces, and a clear sky.

A hotel room with two beds, a bedside table with a phone, a window with curtains, and a wooden floor.

6. Park Inn by Radisson, Medical Center

Medical Center District, 1 km from South Texas Medical Center

Amanda

₩86,974

₩101,543 total

includes taxes & fees

Oct 7 - Oct 8

A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

A clean, modern reception area with a large number '6' sign, a poster advertising a direct book service, and a view of the outside through a window.

A compact kitchen with a built-in refrigerator, microwave, and coffee maker.

A stone facade with a 'welcome' sign, a blue door, and a parking sign.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District, 2.7 km from South Texas Medical Center

Ruben

₩63,157

₩73,736 total

includes taxes & fees

Oct 4 - Oct 5

A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

A hotel reception area with a glass door entrance, a reception desk, and a wall-mounted sign for the OYO hotel.

A room with a table and chairs, a clock, and framed pictures on the wall.

A hotel room with two beds, a television, a desk with a computer, and a door.

8. OYO Inn & Suites Medical Center San Antonio

Medical Center District, 3.1 km from South Texas Medical Center

Melanie

₩68,327

₩86,606 total

includes taxes & fees

Sep 29 - Sep 30

A reception area with a glass door entrance, a reception desk, and a wall-mounted fire extinguisher.

A small, modern room with two brown leather sofas, a black cabinet, and a window with blinds.

A hotel room with a bed, bedside table, desk, chair, TV, and a wardrobe.

A spacious lobby with a large refrigerator, a vending machine, and a seating area.

9. Motel 6 San Antonio, TX - Fiesta Trails

2.9 km from South Texas Medical Center

Alexis

₩60,572

₩70,723 total

includes taxes & fees

Sep 16 - Sep 17

A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

A building with a yellow facade and a sign reading "Flex Studios."

A building with a red roof and a sign reading "Flex Studios."

A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.

10. Flex Studios

Medical Center District, 2.7 km from South Texas Medical Center

Jasper

₩59,030

₩69,779 total

includes taxes & fees

Sep 21 - Sep 22

A modern bedroom with a large bed, bedside tables, a desk, and a chair.

A swimming pool with a stone wall and a 'No Diving' sign, surrounded by a fence and a building with a stone facade.

A hotel reception area with a large number '6' sign, a poster advertising direct booking, and a view of the outside through a window.

A building with a stone facade, a prominent '6' sign, and a parking lot with marked handicapped spaces.

11. Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District, 2.8 km from South Texas Medical Center

Rachel

₩60,372

₩76,731 total

includes taxes & fees

Sep 28 - Sep 29

An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

A multi-story hotel with a central atrium, a parking lot, and surrounding greenery.

An outdoor patio area with multiple tables and chairs, covered by a pergola structure.

A hotel lobby with a curved reception desk, a seating area with a sofa and chairs, and a hallway leading to other rooms.

12. Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 9 km from South Texas Medical Center

Norma

₩126,097

₩149,058 total

includes taxes & fees

Sep 23 - Sep 24

A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.

A hotel room with a brick wall, a wooden headboard, two beds with white bedding, a bedside table with a lamp, and a wall-mounted light fixture.

A conference room with a long table, multiple chairs, and large windows offering a view of greenery and buildings.

A poolside area with lounge chairs and a metal railing.

13. Holiday Inn Express San Antonio-Airport by IHG

9.2 km from South Texas Medical Center

Xiloneen

₩135,981

₩160,742 total

includes taxes & fees

Sep 20 - Sep 21

A covered outdoor seating area with lounge chairs and umbrellas, a pool in the background, and potted plants.

A large, modern hotel with multiple floors and a prominent sign reading "Embassy Suites".

A spacious living area with a large sectional sofa, multiple coffee tables, and a wooden partition.

A modern office space with two desks, chairs, and a large window.

14. Embassy Suites by Hilton San Antonio Landmark

La Cantera District, 8.7 km from South Texas Medical Center

armando

₩219,697

₩259,702 total

includes taxes & fees

Sep 27 - Sep 28

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

A reception desk with a computer, framed pictures on the wall, and pendant lighting.

A hotel entrance with a covered walkway, brick facade, and a sign indicating it is a Heritage Inn & Suites.

An outdoor patio with a pergola, pool, and outdoor seating area.

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown, 9.5 km from South Texas Medical Center

Aaron

₩107,315

₩126,862 total

includes taxes & fees

Sep 21 - Sep 22

A modern hotel with a prominent sign reading "LA QUINTA".

A modern lounge area with wooden and colorful seating, a round table, and a flat-screen TV on the wall.

A reception area with wooden reception desks, a cityscape mural, and a modern chandelier.

A modern kitchen with a large window, a counter with various appliances, and a view of the parking lot.

16. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

9.1 km from South Texas Medical Center

john

₩123,159

₩143,788 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio with a stone fireplace, wicker furniture, and a view of apartment buildings.

A modern bar area with a wooden ceiling, bar stools, and a television.

A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.

A spacious living area with a sofa set, multiple chairs, a coffee table, and a chandelier.

17. Doubletree By Hilton San Antonio Northwest

La Cantera District, 9.7 km from South Texas Medical Center

Vicente

₩205,782

₩205,782 total

includes taxes & fees

Oct 4 - Oct 5

A modern kitchen with a large flat-screen TV, a glass display case with wine glasses, and a breakfast buffet sign.

An outdoor patio area with a barbecue grill, seating arrangements, and potted plants.

An outdoor patio area with seating, a pool, and string lights.

A modern living room with a sofa, two armchairs, a coffee table, and a TV.

18. Staybridge Suites San Antonio Lackland AFB Area by IHG

Far West Side, 9.8 km from South Texas Medical Center

Denise

₩187,143

₩218,486 total

includes taxes & fees

Sep 27 - Sep 28

A modern building with a distinctive roof structure and a large illuminated sign.

A modern lounge area with a pool table, seating, and a colorful rug.

A modern hotel room with a large bed, a desk, and a mirror.

A modern lounge area with a bar, seating arrangements, and a visible bar sign.

19. Aloft by Marriott San Antonio UTSA Area

Northwest Side, 7.3 km from South Texas Medical Center

Mark

₩136,897

₩161,825 total

includes taxes & fees

Sep 20 - Sep 21

A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.

A lobby with a fountain, seating area, and a reception desk.

A spacious bar area with a long counter, multiple stools, and a television screen.

20. Estancia del Norte San Antonio, Tapestry Collection by Hilton

8.7 km from South Texas Medical Center

Iliana

₩164,497

₩194,450 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Compare popular hotels close to South Texas Medical Center

Property	Property class	Guest rating
Drury Inn & Suites San Antonio Northwest Medical Center	9.2 Wonderful 1,449 reviews	View
Fairfield Inn & Suites by Marriott San Antonio Medical Center	9.0 Wonderful 1,078 reviews	View
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW	8.4 Very good 3,657 reviews	View
The Westin San Antonio North	8.4 Very good 1,624 reviews	View
Atria Inn & Suites	7.6 Good 314 reviews	View

Top South Texas Medical Center Hotel Reviews

Courtyard by Marriott Medical Center San Antonio

10/10 Excellent

"Clean quiet hotel"

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

10/10 Excellent

"Everything was great. The pool was really fun and the breakfast was very nice as well."

Atria Inn & Suites

10/10 Excellent

"Had a great stay. Will come back soon."

SpringHill Suites by Marriott San Antonio Medical Center/NW

10/10 Excellent

"Good overall"

Hyatt Place San Antonio-Northwest/Medical Center

10/10 Excellent

"They're alot od breakfast options like hash browns, cereal, and including a waffle maker!! My kids loved the hash browns would definitely come again. The room was amazing and one of my kids got to sleep on the sofa bed, amazing bed my kids was very comfortable!!"

San Antonio Marriott Northwest Medical Center

8/10 Good

"I appreciated the well lit parking lot, clean rooms, and nice view of the main corridor. Checking in and out was easy and quick. Would come again."

Motel 6 San Antonio, TX - Northwest Medical Center

10/10 Excellent

"The customer service rep at check in and housekeeping, we’re very helpful and very courteous."

Flex Studios

10/10 Excellent

"Its not to bad a place. Very affordable and reasonable. I Have stayed at way worse. I plan on staying about two months. I been there two weeks."

Frequently asked questions

What's the area like around South Texas Medical Center?

South Texas Medical Center is located in a walkable area of San Antonio known for its beautiful river views and biking. If you're looking for a convenient place to stay, check out the 34 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to South Texas Medical Center?

Courtyard by Marriott Medical Center San Antonio is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from South Texas Medical Center. Other good options close by include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Park Inn by Radisson, Medical Center.

How many hotels will I find close to South Texas Medical Center?

Expedia has 34 hotels and other accommodations within a mile from South Texas Medical Center.

If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best options available near South Texas Medical Center.

Where can I learn more about changing or cancelling my trip in the area near South Texas Medical Center?

For more information about picking new dates or cancelling your stay near South Texas Medical Center, head over to our customer service page.

What can I see and do near South Texas Medical Center?

You can watch performances at Woodlawn Theater, Sheldon Vexler Theatre, and Laugh Out Loud Comedy Club if you're interested in local theater. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Wonderland of the Americas Mall, Huebner Oaks, and Ingram Park Mall might be just the ticket while you're in the area around South Texas Medical Center.

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Our top choices for South Texas Medical Center hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

4. The Westin San Antonio North

5. Atria Inn & Suites

6. Park Inn by Radisson, Medical Center

7. Studio 6 San Antonio, Tx - Northwest Medical Center

8. OYO Inn & Suites Medical Center San Antonio

9. Motel 6 San Antonio, TX - Fiesta Trails

10. Flex Studios

11. Motel 6 San Antonio, TX - Northwest Medical Center

12. Drury Inn & Suites Near La Cantera Parkway

13. Holiday Inn Express San Antonio-Airport by IHG

14. Embassy Suites by Hilton San Antonio Landmark

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

16. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

17. Doubletree By Hilton San Antonio Northwest

18. Staybridge Suites San Antonio Lackland AFB Area by IHG

19. Aloft by Marriott San Antonio UTSA Area

20. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Compare popular hotels close to South Texas Medical Center

Top South Texas Medical Center Hotel Reviews

Courtyard by Marriott Medical Center San Antonio

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Atria Inn & Suites

SpringHill Suites by Marriott San Antonio Medical Center/NW

Hyatt Place San Antonio-Northwest/Medical Center

San Antonio Marriott Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Frequently asked questions

Find hotels near South Texas Medical Center, San Antonio from ₩69,779

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for South Texas Medical Center hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

4. The Westin San Antonio North

5. Atria Inn & Suites

6. Park Inn by Radisson, Medical Center

7. Studio 6 San Antonio, Tx - Northwest Medical Center

8. OYO Inn & Suites Medical Center San Antonio

9. Motel 6 San Antonio, TX - Fiesta Trails

10. Flex Studios

11. Motel 6 San Antonio, TX - Northwest Medical Center

12. Drury Inn & Suites Near La Cantera Parkway

13. Holiday Inn Express San Antonio-Airport by IHG

14. Embassy Suites by Hilton San Antonio Landmark

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

16. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

17. Doubletree By Hilton San Antonio Northwest

18. Staybridge Suites San Antonio Lackland AFB Area by IHG

19. Aloft by Marriott San Antonio UTSA Area

20. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Compare popular hotels close to South Texas Medical Center

Top South Texas Medical Center Hotel Reviews

Courtyard by Marriott Medical Center San Antonio

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Atria Inn & Suites

SpringHill Suites by Marriott San Antonio Medical Center/NW

Hyatt Place San Antonio-Northwest/Medical Center

San Antonio Marriott Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Frequently asked questions