A forested valley with autumn foliage, a rocky cliff, and a sunset.

Southern Illinois, Illinois hotel rooms at the La Quinta Inn & Suites

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Check prices for these dates

Tonight
Aug 6 - Aug 7
Tomorrow
Aug 7 - Aug 8
This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Eastport
United States
Taylor
₩124,454
₩143,097 total
includes taxes & fees
Sep 6 - Sep 7
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Alexis
₩146,203
₩163,718 total
includes taxes & fees
Aug 30 - Aug 31
La Quinta Inn & Suites by Wyndham Effingham

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
O'Fallon
United States
Tahjae
₩94,886
₩109,100 total
includes taxes & fees
Sep 6 - Sep 7
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
Granite City
United States
Weldon
₩135,329
₩155,602 total
includes taxes & fees
Aug 9 - Aug 10
La Quinta Inn & Suites by Wyndham Pontoon Beach
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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Drury is one of our go-to stays. They are EXCELLENT!!!"
Mary 1-night trip
Posted less than an hour ago
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"This was our 3rd time staying there in 2 months and everything was excellent! The free dinner and drinks is always good!"
Jane 1-night trip
Posted less than an hour ago
Drury Inn & Suites Marion
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

10/10 Excellent
"Staff"
Tina 1-night trip
Posted 7 hours ago
Ramada by Wyndham Effingham
The Principal Hotel

The Principal Hotel

10/10 Excellent
"What a find! We were looking for a hotel outside of St.Louis and asked ChatGPT for suggestions. The overall pick was The Principal. Great ratings, great rate. We were already impressed before we reached the hotel. Columbia is a beautiful city. As we drove down Main St it was like stepping back in time. The hotel has a history you’ll have to discover for yourself. You’ll be very happy you stayed here. Graphite, the restaurant, has to-die-for desserts and Cafe on the Abbey is a must for breakfast (be sure to pick up a pecan brownie to go!). We will be back for sure."
Wayne 1-night trip
Posted 8 hours ago
The Principal Hotel
Baymont by Wyndham Marion

Baymont by Wyndham Marion

10/10 Excellent
"Was a good safe clean place to sleep. Breakfast was nothing to write home about. Nothing hot. No protein. But would stay while traveling again."
Sandi 1-night trip
Posted 22 hours ago
Baymont by Wyndham Marion
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Hot tub was kinda gross. Definitely needed a water change. And the bubbles that you turn on, weren't working well"
Kathleen 1-night trip
Posted 1 day ago
Comfort Suites Mount Vernon
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

8/10 Good
"Water pressure at 5 am was limited to 1/4 it’s normal volume."
Chris 1-night trip
Posted 1 day ago
Holiday Inn Express Metropolis by IHG
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

8/10 Good
"We will be back. Enjoyed our stay."
CANDINA 1-night trip
Posted 3 days ago
Baymont by Wyndham Effingham

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