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Check availability on Southwest Illinois Business Hotels

Our top choices for Southwest Illinois business-friendly hotels

Lobby lounge

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,656 reviews)
"Hotel is very clean, nicely furnished and the beds were so comfy!"
United States
Christina
The price is ₩163,250
₩184,066 total
includes taxes & fees
Mar 22 - Mar 23
Drury Plaza Hotel Mt. Vernon
Free daily continental breakfast

Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (401 reviews)
"Good staff "
United States
Jose Diego
The price is ₩127,130
₩138,544 total
includes taxes & fees
Feb 21 - Feb 22
Best Western U. S. Inn
Lobby

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (931 reviews)
"Great place to stay."
United States
Stephen
The price is ₩110,514
₩122,649 total
includes taxes & fees
Mar 4 - Mar 5
SureStay Hotel by Best Western Whittington Rend Lake
Lobby

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,002 reviews)
"All of the above, enjoyed the evening meal and breakfast, also staff was very friendly. "
United States
Barbara
The price is ₩142,409
₩170,862 total
includes taxes & fees
Mar 3 - Mar 4
Drury Inn & Suites Marion
Lobby

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (428 reviews)
"Great place to stay. Friendly front desk staff, comfortable rooms. "
United States
Douglas
The price is ₩130,942
₩145,319 total
includes taxes & fees
Mar 8 - Mar 9
Comfort Inn & Suites Greenville I-70
Lobby

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (819 reviews)
"The room was clean, the staff was friendly, respectful and very helpful "
United States
Dianna
The price is ₩98,248
₩107,076 total
includes taxes & fees
Feb 22 - Feb 23
Ramada by Wyndham Vandalia
Exterior

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (523 reviews)
"Yes, very clean and service was great."
United States
allen
The price is ₩149,690
₩166,126 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
In-room safe, desk, iron/ironing board, cribs/infant beds

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very Good, (1,000 reviews)
"I always stay at this hotel when visiting! Its updated and the staff is so attentive!"
United States
Anessa
The price is ₩89,651
₩97,699 total
includes taxes & fees
Feb 26 - Feb 27
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Reception

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (614 reviews)
"Very beautiful place to stay "
United States
Valerie
The price is ₩160,664
₩179,909 total
includes taxes & fees
Mar 18 - Mar 19
Best Western Plus Centralia Hotel & Suites
Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.6 out of 10, Excellent, (360 reviews)
"The room was clean and the staff were friendly. "
United States
RODNEY
The price is ₩110,451
₩122,579 total
includes taxes & fees
Feb 22 - Feb 23
Baymont by Wyndham Chester IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"One of the better hotels I have stayed at! Super clean. Great service! Good food options! Liked the evening and breakfast offerings. Very pet friendly. Safe and secure!"
Richard 1-night trip
Posted 3 days ago
Drury Plaza Hotel Mt. Vernon

Frequently asked questions

How much do business-friendly hotels in Southwest Illinois cost?
You'll pay between ₩97,699 and ₩184,066 per night for business-friendly hotels in Southwest Illinois. Top deals on stays that cater to work-related travelers are only a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southwest Illinois?
There are multiple business-friendly hotels in Southwest Illinois with a total average guest review rating of 8.9, so you're sure to discover the perfect place. On your way to O'Fallon? Drury Inn & Suites St. Louis O'Fallon, IL is a top pick with corporate travelers. This 3-stars option has amenities like a swimming pool and WiFi. Hampton Inn O'Fallon also scores top marks from business guests. Take advantage of a swimming pool and an electric car charging station at this 2.5-stars escape in O'Fallon.
How many business-friendly hotels are there in Southwest Illinois?
Southwest Illinois has 105 business-friendly hotels to choose from. Whether you're attending a conference or meeting or simply working remotely, these properties are equipped with the amenities you need to keep you comfortable and productive.
What are the best cheap business-friendly hotels in Southwest Illinois?
When you need to make and close deals on the go in Southwest Illinois, Expedia will help you find the perfect business-friendly hotel. Hampton Inn O'Fallon is a popular budget option in O'Fallon. An electric car charging station and a swimming pool are among its many amenities. In search of low-cost stays in Marion? Comfort Inn & Suites Marion I-57 is recommended by many corporate guests. It comes with conveniences that make it easy to both work and relax, including pool sun loungers and a swimming pool. Business-friendly hotels in Southwest Illinois start at just ₩97,699 a night. Like to sightsee around Southwest Illinois without the high admission prices? Take a break from your work commitments to visit awesome free attractions like St. Clair Bowl in O'Fallon. Marion also has many things to do that don't cost a penny, including Williamson County Historical Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southwest Illinois that are also business friendly?
If you're traveling for business in Southwest Illinois and bringing family along with you, Expedia will help you locate a cozy and convenient stay. Drury Inn & Suites St. Louis O'Fallon, IL in O'Fallon is the perfect option for those combining work and pleasure. This 3-stars property comes with all the necessary amenities, like complimentary breakfast and a laundry service. Drury Inn & Suites St. Louis Fairview Heights is another terrific choice in O'Fallon. Get the best of both worlds — combine corporate travel and quality time with your family at this 3-stars property. Complimentary breakfast and WiFi are among the conveniences you'll find here. Once you've gotten work out of the way, get out and see O'Fallon with the kids. Popular family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southwest Illinois with Expedia?
At Expedia, our top task is to help you land the ideal stay at the right price. From upmarket, corporate-friendly properties to affordable motels filled with all the amenities you need, you'll have your next work trip arranged in a few simple clicks.
How can I find cheap business-friendly hotels in Southwest Illinois?
When work takes you to Southwest Illinois, our "business friendly" filter will help you find a suitable hotel. From fast WiFi to meeting rooms and workspaces, they come with the amenities you need for a comfortable and productive stay. Another tip? Narrow your search by your budget and preferred star rating to see the cheapest accommodations.
What is there to do in Southwest Illinois near my business-friendly hotel?
Wherever your travels take you in Southwest Illinois, there's plenty to keep you busy. Staying a few days in O'Fallon? The Edge is a top attraction to include on your itinerary.