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Our top choices for Substance hotels

Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
Downtown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,649 reviews)
"Clean, helpful staff, great view, great pool, good food"
United States
Kelsey
The price is ₩180,549
₩289,743 total
includes taxes & fees
Jun 16 - Jun 17
Circa Resort & Casino – Adults Only

Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery
2.5 star property
Downtown Las Vegas, 0.6 km from Substance
9.0 out of 10, Wonderful, (3,359 reviews)
"Nice people, clean rooms, great food, buffet is the best! would absolutely stay here again."
United States
Nathan J
The price is ₩37,187
₩98,583 total
includes taxes & fees
Jun 28 - Jun 29
Main Street Station Hotel, Casino and Brewery

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
Arts District, 1.4 km from Substance
9.4 out of 10, Exceptional, (129 reviews)
"Excellent property "
United States
Leroy
The price is ₩175,998
₩198,878 total
includes taxes & fees
Jun 21 - Jun 22
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,157 reviews)
"Great stay"
United States
Ronald
The price is ₩89,516
₩101,153 total
includes taxes & fees
Jul 6 - Jul 7
Four Queens Hotel and Casino

Element by Marriott Las Vegas Symphony Park

Element by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
9.2 out of 10, Wonderful, (107 reviews)
"very clean room, easy access, good breakfast, good parking"
United States
Joanna
The price is ₩168,943
₩228,837 total
includes taxes & fees
Jul 1 - Jul 2
Element by Marriott Las Vegas Symphony Park

El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over
3.0 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very Good, (7,244 reviews)
"We will definitely stay there again."
United States
Jose Armando
The price is ₩57,988
₩116,963 total
includes taxes & fees
Jul 13 - Jul 14
El Cortez Hotel and Casino - 21 and Over

Hotel Apache

Hotel Apache
3.5 star property
Downtown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very Good, (1,138 reviews)
"front desk was amazing and casino had great drink service"
Canada
Darren
The price is ₩58,479
₩66,081 total
includes taxes & fees
Jul 9 - Jul 10
Hotel Apache

Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very Good, (10,025 reviews)
"Great absolutely would stay there again"
United States
Michael
The price is ₩59,172
₩133,728 total
includes taxes & fees
Jun 15 - Jun 16
Downtown Grand Las Vegas

the D Las Vegas

the D Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very Good, (7,501 reviews)
"Great breakfast deal at their restaurant"
United States
Bertha
The price is ₩43,999
₩118,206 total
includes taxes & fees
Jun 16 - Jun 17
the D Las Vegas

AC Hotel by Marriott Las Vegas Symphony Park

AC Hotel by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (214 reviews)
"Beautiful hotel, great location! Would definitely stay here again."
United States
Luis Alberto
The price is ₩154,756
₩212,805 total
includes taxes & fees
Jul 5 - Jul 6
AC Hotel by Marriott Las Vegas Symphony Park

Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very Good, (13,492 reviews)
"Our stay was fantastic!"
United States
Cheyenne
The price is ₩45,891
₩131,486 total
includes taxes & fees
Jun 16 - Jun 17
Golden Nugget Las Vegas Hotel & Casino

Fremont Hotel & Casino

Fremont Hotel & Casino
3.0 star property
Downtown Las Vegas, 0.3 km from Substance
8.8 out of 10, Excellent, (4,337 reviews)
"Great place to stay."
United States
John
The price is ₩38,917
₩102,253 total
includes taxes & fees
Jun 29 - Jun 30
Fremont Hotel & Casino

Plaza Hotel & Casino

Plaza Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.6 km from Substance
8.2 out of 10, Very Good, (5,281 reviews)
"Had a great time it’s a wonderful place to stay"
United States
Susan
The price is ₩46,426
₩119,326 total
includes taxes & fees
Jun 15 - Jun 16
Plaza Hotel & Casino

Oasis at Gold Spike

Oasis at Gold Spike
3.5 star property
Downtown Las Vegas, < 0.1 km from Substance
8.0 out of 10, Very Good, (2,277 reviews)
"Very cozy and fun place to stay! "
United States
Alexis
The price is ₩53,254
₩94,477 total
includes taxes & fees
Jun 22 - Jun 23
Oasis at Gold Spike

Desert Moon Motel

Desert Moon Motel
2.5 star property
Downtown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very Good, (498 reviews)
"It may not seem like much from the outside but the rooms are really nice with a lot of amenities. Clean and comfy beds and a nice tv."
United States
maricsa
The price is ₩83,775
₩94,665 total
includes taxes & fees
Jul 12 - Jul 13
Desert Moon Motel

Downtowner Boutique Hotel

Downtowner Boutique Hotel
3.0 star property
Downtown Las Vegas, 0.4 km from Substance
7.6 out of 10, Good, (40 reviews)
"Great AC, clean rooms, knowledgeable staff, very close to Freemont street perfect for a fun weekend."
United States
Vivianna
The price is ₩46,426
₩86,751 total
includes taxes & fees
Jun 14 - Jun 15
Downtowner Boutique Hotel

Golden Gate Hotel and Casino

Golden Gate Hotel and Casino
2.5 star property
Downtown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,067 reviews)
"Fun stay"
United States
Thomas
The price is ₩36,413
₩109,634 total
includes taxes & fees
Jun 15 - Jun 16
Golden Gate Hotel and Casino

Bposhtels Las Vegas

Bposhtels Las Vegas
2.5 star property
1.8 km from Substance
7.6 out of 10, Good, (293 reviews)
"Clean and safe. Would definitely stay there again."
United States
Hugo
The price is ₩40,055
₩62,404 total
includes taxes & fees
Jun 21 - Jun 22
Bposhtels Las Vegas

The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower
4.0 star property
Las Vegas Strip, 2.9 km from Substance
7.6 out of 10, Good, (23,493 reviews)
"Great place to stay!"
United States
Ronald
The price is ₩20,482
₩109,142 total
includes taxes & fees
Jun 14 - Jun 15
The STRAT Hotel, Casino & Tower

Thunderbird Hotel

Thunderbird Hotel
2.5 star property
Gateway District, 1.8 km from Substance
7.2 out of 10, Good, (1,002 reviews)
"Clean and spacious and quiet room easy parking"
United States
Chandramouli
The price is ₩61,447
₩98,574 total
includes taxes & fees
Jun 15 - Jun 16
Thunderbird Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Substance

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Exterior
Circa Resort & Casino – Adults Only
4.5 star property
9.4
Exceptional
5,649 reviews
View
Daily buffet breakfast for a fee
Main Street Station Hotel, Casino and Brewery
2.5 star property
9.0
Wonderful
3,359 reviews
View
Exterior
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
9.4
Exceptional
129 reviews
View
In-room safe, blackout drapes, iron/ironing board, free WiFi
Four Queens Hotel and Casino
3.5 star property
8.6
Excellent
7,157 reviews
View
View from property
Element by Marriott Las Vegas Symphony Park
3.0 star property
9.2
Wonderful
107 reviews
View

Top Substance Hotel Reviews

Hotels near other Substance attractions

Frequently asked questions

What's the area like around Substance?
Substance is located in Las Vegas. This welcoming area is known for its array of dining options and bar scene. If you're looking for a convenient place to stay, check out the 174 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Substance?
Adjacent to Substance, Golden Nugget Las Vegas Hotel & Casino is one of the top choices for your stay based on our traveler data, and this resort offers 2 outdoor pools and a full-service spa. Other good options within a short distance include Downtown Grand Las Vegas and Fremont Hotel & Casino.
How many hotels are there close to Substance?
Expedia has 174 hotels and other accommodations within a mile from Substance.
If I need to cancel the hotel reservation for my stay near Substance, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review top deals close to Substance.
Where can I learn more about changing or cancelling my trip in the area near Substance?
For more details about rescheduling or cancelling your stay near Substance, click here.
What can I see and do near Substance?
You might want to spend some time browsing the exhibits at Mob Museum, The Neon Museum, or Zak Bagans Haunted Museum. Old Las Vegas Mormon Fort State Historic Park, Harrison House, and First AME Church are monuments to see when you're exploring the area around Substance. You can watch performances at Colosseum at Caesars Palace, Sphere, and Dolby Live if you're interested in local theater.