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Nov 6 - Nov 8
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Nov 13 - Nov 15

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Our top choices for Substance hotels

A rooftop lounge with a fire pit, large windows, and a city view.

1. Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
Downtown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,765 reviews)
"Great location and good restaurants"
United States
John
The price is ₩158,744
₩254,750 total
includes taxes & fees
Nov 4 - Nov 5
Circa Resort & Casino – Adults Only
A spacious dining area with wooden tables and chairs, ornate ceiling design, and a central decorative piece.

2. Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery
2.5 star property
Downtown Las Vegas, 0.6 km from Substance
9.0 out of 10, Wonderful, (3,926 reviews)
"Great place to stay!!!"
United States
Michelle
The price is ₩39,219
₩94,048 total
includes taxes & fees
Nov 16 - Nov 17
Main Street Station Hotel, Casino and Brewery
A bar area with a leather couch, red chairs, and a bar counter.

3. Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.6 out of 10, Excellent, (9,959 reviews)
"Great place"
United States
Chase
The price is ₩55,560
₩121,571 total
includes taxes & fees
Nov 15 - Nov 16
Downtown Grand Las Vegas
An outdoor seating area with a wooden bench, a table with food, potted plants, and a view of the building's interior through a glass door.

4. AC Hotel by Marriott Las Vegas Symphony Park

AC Hotel by Marriott Las Vegas Symphony Park
2.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (295 reviews)
"The best hotel period."
United States
Janaina
The price is ₩165,414
₩220,267 total
includes taxes & fees
Nov 8 - Nov 9
AC Hotel by Marriott Las Vegas Symphony Park
A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

5. Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,463 reviews)
"Always a nice place to stay"
United States
jose
The price is ₩92,042
₩104,007 total
includes taxes & fees
Nov 8 - Nov 9
Four Queens Hotel and Casino
A modern reception desk with vertical light fixtures and a marble counter.

6. Element by Marriott Las Vegas Symphony Park

Element by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (160 reviews)
"Spotless, brand-new feel in a quiet location ​Fantastic hotel! It was clean, quiet, and still smelled brand new. Staying in Symphony Park provided a relaxing break from the busy Strip while keeping us close to our festival venue. Modern, great facilities, and a wonderful overall stay."
United States
Suzanne
The price is ₩178,753
₩235,341 total
includes taxes & fees
Nov 23 - Nov 24
Element by Marriott Las Vegas Symphony Park
A brick-walled interior with a wooden floor and a black metal railing.

7. the D Las Vegas

the D Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.6 out of 10, Excellent, (7,733 reviews)
"Nice place to stay."
United States
Dave
The price is ₩38,685
₩103,931 total
includes taxes & fees
Nov 9 - Nov 10
the D Las Vegas
A spacious lobby with a stone floor, wooden beams, and a large chandelier.

8. El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over
3.0 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (7,060 reviews)
"I loved our stay. The rooms were cute and conveniently across the casino!"
United States
Evelia
The price is ₩49,595
₩101,264 total
includes taxes & fees
Dec 2 - Dec 3
El Cortez Hotel and Casino - 21 and Over
A large, modern steakhouse with a curved roof and multiple dining areas, surrounded by other buildings.

9. Plaza Hotel & Casino

Plaza Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.6 km from Substance
8.4 out of 10, Very good, (5,725 reviews)
"The location is great free parking and breakfast options"
United States
saul
The price is ₩46,822
₩111,697 total
includes taxes & fees
Nov 30 - Dec 1
Plaza Hotel & Casino
A restaurant with a view of a neon-lit building and a large screen displaying an image of a person.

10. Hotel Apache

Hotel Apache
3.5 star property
Downtown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very good, (1,169 reviews)
"Always a nice place to stay"
United States
jose
The price is ₩65,371
₩73,870 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Apache
A bedroom with a bed, a small table, and a chair. There is a bathroom with a sink, mirror, and shower.

11. Desert Moon Motel

Desert Moon Motel
2.5 star property
Downtown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very good, (522 reviews)
"A great value for an extremely nice and clean hotel room. Great staff and location too !"
United States
Grant
The price is ₩66,112
₩74,706 total
includes taxes & fees
Dec 2 - Dec 3
Desert Moon Motel
A hotel with a prominent sign reading "California Hotel & Casino."

12. California Hotel and Casino

California Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.5 km from Substance
8.8 out of 10, Excellent, (1,475 reviews)
"Friendly staff and clean rooms"
United States
Zoe
The price is ₩42,487
₩97,741 total
includes taxes & fees
Nov 16 - Nov 17
California Hotel and Casino
A hotel with a large indoor pool, palm trees, and a modern building in the background.

13. Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very good, (14,838 reviews)
"Wonderful stay, clean rooms, comfy beds, large bathrooms, and lovely restaurants!"
United States
Andrea
The price is ₩47,224
₩122,702 total
includes taxes & fees
Nov 9 - Nov 10
Golden Nugget Las Vegas Hotel & Casino
A hotel room with two beds, a desk, a chair, a large mirror, and a decorative wall with geometric patterns.

14. Downtowner Boutique Hotel

Downtowner Boutique Hotel
3.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.0 out of 10, Very good, (186 reviews)
"Cute clean hotel, located just off the hustle and bustle of Fremont street."
United States
Nicholas
The price is ₩46,822
₩83,058 total
includes taxes & fees
Nov 8 - Nov 9
Downtowner Boutique Hotel
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and tall buildings.

15. Oasis at Gold Spike

Oasis at Gold Spike
3.5 star property
Downtown Las Vegas, < 0.1 km from Substance
8.2 out of 10, Very good, (2,344 reviews)
"Great hotel"
United States
Zachary
The price is ₩66,992
₩113,386 total
includes taxes & fees
Nov 8 - Nov 9
Oasis at Gold Spike
A nighttime view of a pool area with a city skyline in the background, including a prominent tower.

16. Bposhtels Las Vegas

Bposhtels Las Vegas
2.5 star property
1.8 km from Substance
7.8 out of 10, Good, (352 reviews)
"The manager was very kind The house keeping was great and polite I. Would love to stay again but now have a local id Thanks Nichole"
United States
Nichole
The price is ₩30,682
₩49,745 total
includes taxes & fees
Nov 5 - Nov 6
Bposhtels Las Vegas
A hotel with a prominent tower and the name "STRAT" illuminated on the facade.

17. The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower
4.0 star property
Las Vegas Strip, 2.9 km from Substance
7.6 out of 10, Good, (25,964 reviews)
"I love staying here when I visit!"
United States
Steve
The price is ₩18,009
₩95,962 total
includes taxes & fees
Nov 11 - Nov 12
The STRAT Hotel, Casino & Tower
The exterior of the Golden Gate Hotel with a prominent sign, a modern architectural design, and a parking lot with visible cars.

18. Golden Gate Hotel and Casino

Golden Gate Hotel and Casino
2.5 star property
Downtown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,169 reviews)
"Great place to stay"
United States
Christian
The price is ₩32,016
₩96,394 total
includes taxes & fees
Nov 9 - Nov 10
Golden Gate Hotel and Casino
A hotel room with a large bed, a bedside table, a chair, a desk, and a mirror.

19. Crown Motel

Crown Motel
2.5 star property
Sunrise Manor, 3.1 km from Substance
7.4 out of 10, Good, (80 reviews)
"Decent hotel"
United States
Jeff
The price is ₩178,887
₩215,482 total
includes taxes & fees
Nov 10 - Nov 11
Crown Motel
An outdoor seating area with wicker furniture, palm trees, and a clear sky.

20. Thunderbird Hotel

Thunderbird Hotel
2.5 star property
Gateway District, 1.8 km from Substance
7.2 out of 10, Good, (1,004 reviews)
"Great location clean room and bedding"
United States
Edgar
The price is ₩54,026
₩86,676 total
includes taxes & fees
Nov 4 - Nov 5
Thunderbird Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Substance

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A rooftop lounge with a fire pit, large windows, and a city view.
Circa Resort & Casino – Adults Only
4.5 star property
9.4
Exceptional
5,765 reviews
View
A spacious dining area with wooden tables and chairs, ornate ceiling design, and a central decorative piece.
Main Street Station Hotel, Casino and Brewery
2.5 star property
9.0
Wonderful
3,926 reviews
View
A bar area with a leather couch, red chairs, and a bar counter.
Downtown Grand Las Vegas
3.5 star property
8.6
Excellent
9,959 reviews
View
An outdoor seating area with a wooden bench, a table with food, potted plants, and a view of the building's interior through a glass door.
AC Hotel by Marriott Las Vegas Symphony Park
2.0 star property
8.8
Excellent
295 reviews
View
A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.
Four Queens Hotel and Casino
3.5 star property
8.6
Excellent
7,463 reviews
View

Top Substance Hotel Reviews

Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery

8/10 Good
"Clean room, clean hotel. A bit loud at 3 am both nights and there is a giant haulaway trash bin for metal items located just behind the property. Constructions crews before heading out in the morning would dump numerous metallic items into the metal trash bin creating a loud ruckus for several minutes."
Matthew 2-night trip
Posted less than an hour ago
Main Street Station Hotel, Casino and Brewery

Other attractions near Substance

The exterior of the Neonopolis building with the Telemundo Las Vegas sign above.

Neonopolis

You can spend time studying the exhibits at Neonopolis during your travels in Las Vegas. Discover the entertainment choices and casinos in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Substance?
Substance is located in Las Vegas. This welcoming area is known for its array of dining options and bar scene. If you're looking for a convenient place to stay, check out the 156 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Substance?
Adjacent to Substance, Golden Nugget Las Vegas Hotel & Casino is one of the top choices for your stay based on our traveler data, and this resort offers 2 outdoor pools and a full-service spa. Other good options within a short distance include Plaza Hotel & Casino and Downtown Grand Las Vegas.
How many hotels are there close to Substance?
Expedia has 156 hotels and other accommodations within a mile from Substance.
If I need to cancel the hotel reservation for my stay near Substance, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review top deals close to Substance.
Where can I learn more about changing or cancelling my trip in the area near Substance?
For more details about rescheduling or cancelling your stay near Substance, click here.
What can I see and do near Substance?
You might want to spend some time browsing the exhibits at Mob Museum, The Neon Museum, or Zak Bagans Haunted Museum. Old Las Vegas Mormon Fort State Historic Park, Harrison House, and First AME Church are monuments to see when you're exploring the area around Substance. You can watch performances at Colosseum at Caesars Palace, Sphere, and Dolby Live if you're interested in local theater.