Photo by Southernmost Illinois Tourism Bureau

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Top Adventure Southern Illinois Hotels

Best Western Heartland Inn

1416 Broadway Avenue East Mattoon IL

5 hours drive from Shawnee National Forest

Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

8.2/10 Very Good! (566 reviews)

Check in was friendly and quick, room was spacious and comfortable, breakfast was delicious. Highly recommended!!

Reviewed on Mar 16, 2026

SureStay Hotel by Best Western Whittington Rend Lake

13277 Freeway Lane Whittington IL

2 hours drive from Shawnee National Forest

Book a stay at this business-friendly hotel in Whittington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.8/10 Excellent! (935 reviews)

Staff was amazing and friendly! Our room was clean and comfy. Would stay here again.

Reviewed on Mar 15, 2026

Hampton Inn Carbondale

2175 Reed Station Pkwy Carbondale IL

2 hours drive from Shawnee National Forest

Book a stay at this business-friendly hotel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.4/10 Very Good! (625 reviews)

Clean Room, Friendly Staff

Reviewed on Mar 4, 2026

See all 1,161 properties in Southern Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.