Northeast Missouri Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
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- Better togetherSave up to ₩1,660,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
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Top Luxury Northeast Missouri Hotels
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
- 6 min drive from St. Louis Union Station
Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...
9.2/10 Wonderful! (1,012 reviews)
"All modern amenities with a touch of old world glam! Across from a beautiful walking/biking park and equipped with a beautiful pool, workout facility, comfortable beds, and several restaurants, all you need to have a wonderful travel experience!"
Reviewed on Sep 1, 2026
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
- 34 min drive from St. Louis Union Station
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
- 13 min drive from St. Louis Union Station
Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The 3 bars, fitness ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
