Photo by Visit Mississippi Gulf Coast

Plan, book, travel with confidence
Better together
Save up to ₩1,660,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Mississippi Gulf Coast Hotels

Beau Rivage

875 Beach Blvd Biloxi MS

1 min walk from Beau Rivage Casino

Treat yourself to a decadent stay at Beau Rivage, where you'll find deep soaking bathtubs and pillowtop beds. Notable amenities include a casino, a spa, and ...

9.4/10 Exceptional! (1,436 reviews)

"Outstanding resort. Staff was extremely friendly and helpful. Room was clean and very comfortable. Food was good. Close to concert venue and shopping in Ocean Springs. We will definitely be back. My wife left her air pods in the room. The staff was extremely helpful retrieving them from lost and ..."

Reviewed on Oct 27, 2026

Margaritaville Resort Biloxi

195 Beach Blvd Biloxi MS

21 min walk from Beau Rivage Casino

Choose luxury at Margaritaville Resort Biloxi, where you can enjoy amenities like pillowtop beds, flat-screen TVs, and more. Notable amenities include 2 bars, ...

8.6/10 Excellent! (6,467 reviews)

"We had a wonderful time here!! Everyone was so very nice and accommodating. We took our grandson for his 4th birthday and it was amazing!! We will be back, for sure!"

Reviewed on Oct 29, 2026

White House Hotel

1230 Beach Blvd Biloxi MS

14 min walk from Beau Rivage Casino

Be treated to a luxury stay at White House Hotel, where you can enjoy amenities like plush bedding, premium channels, and more. Deluxe amenities at this hotel ...

9/10 Wonderful! (1,093 reviews)

"Liked that we had bed made every day & room was clean when we came back to our room. Lighting in our bathroom was very dim. Could use higher wattage bulbs. Ice machine was only available on 1st floor & when where is a Private event you have to walk down to the ice machine. Could be real problem if ..."

Reviewed on Oct 27, 2026

See all 3,056 properties in Mississippi Gulf Coast

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.