From our exclusive offers to our rewards program and member prices, you’re guaranteed to save when you book your rental with Expedia. And with suppliers in Downtown South San Francisco to select from, you have ample choice when it comes to finding your perfect set of wheels. But we don’t just offer outstanding rates on rental cars. Flights, hotels and activities can be added to your itinerary to create a personalized Downtown South San Francisco vacation package. The more you bundle, the bigger the savings!