Downtown South San Francisco, CA

San Francisco

An aerial view of a city with a large stadium, several schools, and a dense residential area.
An aerial view of a coastal city with a dense urban area, a large port, and a mountainous backdrop.
A panoramic view of San Francisco's South Peninsula, highlighting the city's dense urban areas, rolling hills, and the iconic Golden Gate Bridge in the distance.

Downtown South San Francisco Hotel Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is ₩158,510 per night from Sep 20 to Sep 21
₩158,510
₩185,580 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
8.2/10 Very Good! (2,125 reviews)
"Very friendly staff and the hotel very clean breakfast was ok. The room I was staying always smell like weed the first two days."

Reviewed on Sep 13, 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is ₩215,528 per night from Sep 20 to Sep 21
₩215,528
₩253,666 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is ₩222,873 per night from Sep 18 to Sep 19
₩222,873
₩317,584 total
Sep 18 - Sep 19
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is ₩197,168 per night from Sep 20 to Sep 21
₩197,168
₩232,057 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Handlery Union Square Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is ₩158,416 per night from Sep 20 to Sep 21
₩158,416
₩186,448 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (3,212 reviews)
"The hotel was under construction but they still managed to keep clear paths in and out of the building. Parking was a little harder with construction but the rooms, restaurant and staff were great ."

Reviewed on Sep 13, 2026

Hilton San Francisco Financial District
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
The price is ₩202,850 per night from Sep 21 to Sep 22
₩202,850
₩239,020 total
Sep 21 - Sep 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...
9.4/10 Exceptional! (3,451 reviews)
"Somewhat dissapointing"

Reviewed on Sep 12, 2026

Chancellor Hotel on Union Square
See all 4,283 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Oracle Park and San Francisco Bay are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Downtown South San Francisco, CA