A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Defiance Vacation Rentals

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Check prices for these dates

In two weeks
Jul 24 - Jul 26
In two months
Sep 4 - Sep 6
In three months
Oct 2 - Oct 4
In four months
Oct 30 - Nov 1

Our top choices for Defiance vacation rentals

Apartment (0 Bedroom) | Interior

Lovely Couples Escape on Mississippi River!

Lovely Couples Escape on Mississippi River!
3.0 star property
St. Charles
10.0 out of 10, Exceptional, (3 reviews)
"Amazing place to stay, quiet and relaxing would definitely stay there again"
United States
Lissette
The price is ₩218,808
₩366,503 total
includes taxes & fees
Jul 15 - Jul 16
Lovely Couples Escape on Mississippi River!
Studio Suite, 1 King Bed | Desk, laptop workspace, blackout drapes, WiFi

Value Suites Extended Stay - St Louis

Value Suites Extended Stay - St Louis
3.0 star property
Westport
7.0 out of 10, Good, (1,110 reviews)
"We’ve stayed here twice before and have always been pleased with everything. Very good hotel close to what we need."
United States
Timothy
The price is ₩575,140
₩790,442 total
includes taxes & fees
Aug 4 - Aug 5
Value Suites Extended Stay - St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Best Western Plus Fenton

Best Western Plus Fenton

10/10 Excellent
"Overall amazing stay, was only 1 night but still very impressed, only thing was, I left my Netflix logged on, I called back and the FD person told me he would go to my room to log me out. So anyone in the future, if you. Log. Onto Netflix, do t forget to log out before you leave!!!!!"
Michael 1-night trip
Posted 5 hours ago
Best Western Plus Fenton

Find out more about Defiance

Search for Vacation rentals in Defiance on Expedia.co.uk! You can easily find your home rentals, villas, Vacation apartments in Defiance using one of the methods below:

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Frequently asked questions

Can I find vacation rentals in Defiance?

Yes, there are vacation rentals close to popular sights in Defiance, or you can choose a more secluded option if you're looking for relaxation. Defiance is known for its wineries and parks.

How many vacation rentals will I find in Defiance?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Defiance stay.

What’s there to see and do in Defiance?

August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. Other places in town to visit include Chandler Hill Vineyards and Sugar Creek Winery.

What’s a vacation rental in Defiance like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Defiance. Vacation rentals feature amenities like laundry facilities and kitchens so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great option for families.