Fort Myers River District Vacations

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Where to stay in Fort Myers River District

Find the best Fort Myers River District areas and neighborhoods for the activities you enjoy most. Learn more about Fort Myers River District
Aerial view of the road bridge between Captiva Island and Sanibel Island in Lee County, Florida, United States

Iona

While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.

Find hotels in Iona

Fort Myers River District Hotel Deals

Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

3 out of 5
2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩158,915 per night from Jul 6 to Jul 7
₩158,915
₩177,190 total
Jul 6 - Jul 7
includes taxes & fees
9.2/10 Wonderful! (987 reviews)
"Stayed I. A King room with a microwave and fridge. Great value with Hilton Honors membership. Self-serve breakfast was included: with hot and cold options, including scrambled and hard boiled eggs, sausage or bacon, fried potatoes, oatmeal with choice of toppings, pastries and waffles, and cold cereals. ..."

Reviewed on Jun 7, 2026

Hampton Inn Fort Myers Downtown
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩372,395 per night from Jun 14 to Jun 15
₩372,395
₩469,755 total
Jun 14 - Jun 15
includes taxes & fees
8.6/10 Excellent! (1,012 reviews)
"We absolutely loved staying here! Everyone was so nice and helpful. 11/10 experience. Will be back!"

Reviewed on Jun 7, 2026

Marriott Sanibel Harbour Resort & Spa
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ₩321,133 per night from Jun 22 to Jun 23
₩321,133
₩436,250 total
Jun 22 - Jun 23
includes taxes & fees
9/10 Wonderful! (2,176 reviews)
"Fabulous resort, excellent everything, food, pool, service, location, WOW! Only downfall for us was its huge, lots n lots of walking, (we’re old and decrepit)."

Reviewed on Jun 6, 2026

Margaritaville Beach Resort Fort Myers
See all 13,785 properties in Fort Myers River District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Fort Myers River District vacation package cost?
Perhaps less than you imagined — from a low , actually! By combining hotels, flights and car rentals into a tailor-made vacation package, your trip to Fort Myers River District is just clicks away.
How do I get a cheap travel package to Fort Myers River District?
Combine your flight and hotel bookings, add extras such as activities or a rental car, and save with a Fort Myers River District vacation package. You won't just walk away with exciting discounts on your adventure — you'll have a world of choice too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 properties around the world. Your affordable vacation starts right here, right now!
How far in advance should I book my Fort Myers River District vacation?
Be rewarded with the widest variety and the lowest prices by booking your trip to Fort Myers River District early. Airlines usually sell flights around 12 months in advance, so start your planning as soon as possible. Having said that, Expedia is constantly working to give you the best bargains around, so there's never a bad time to book your dream vacation!
What does an Expedia Fort Myers River District travel package include?
Car rentals, flights and hotels — we connect you to the very best deals. All you'll have to do is figure out your preferred combination. After you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it simple to create an amazing Fort Myers River District vacation.
What should I know before booking a Fort Myers River District travel package?
Our prices are always low. However, you'll enjoy an even better deal when you book your flights, hotels and car rentals together. With an Expedia package, you'll always get transparent pricing and loads of choice.
Can I choose my airline with a Fort Myers River District Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just choose the carrier that suits you and put together your ideal Fort Myers River District getaway.
If I'm not able to travel, can I cancel my Fort Myers River District vacation package?
If your vacation plans in Fort Myers River District have changed, it's comforting to know that it's possible to cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may charge a fee. For more information, check our Customer Service Portal.

Discover the most popular places to visit in Fort Myers River District

Edison and Ford Winter Estates

Edison and Ford Winter Estates

Explore the winter estates of two of the most famous men in American history. Tour their houses and gardens and learn more about their lives in the museum.

Edison and Ford Winter Estates
Port Sanibel Marina

Port Sanibel Marina

Explore the waterfront in Fort Myers with a trip to Port Sanibel Marina. Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.

Port Sanibel Marina
Six Mile Cypress Slough Preserve

Six Mile Cypress Slough Preserve

From the comfort of elevated boardwalks, walk among the turtles, otters, alligators and other creatures that call this wetlands home.

Six Mile Cypress Slough Preserve
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.