Fort Myers River District Vacations

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Where to stay in Fort Myers River District

Find the best Fort Myers River District areas and neighborhoods for the activities you enjoy most. Learn more about Fort Myers River District
Aerial view of the road bridge between Captiva Island and Sanibel Island in Lee County, Florida, United States

Iona

While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.

Find hotels in Iona

Fort Myers River District Hotel Deals

Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

3 out of 5
2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩221,044 per night from Apr 5 to Apr 6
₩221,044
₩246,464 total
Apr 5 - Apr 6
includes taxes & fees
9.2/10 Wonderful! (917 reviews)
Not much good shopping but more restaurants than anything!

Reviewed on Mar 22, 2026

Hampton Inn Fort Myers Downtown
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ₩540,014 per night from Apr 19 to Apr 20
₩540,014
₩677,577 total
Apr 19 - Apr 20
includes taxes & fees
9/10 Wonderful! (1,955 reviews)
Beautiful in side and out

Reviewed on Mar 22, 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is ₩554,902 per night from Apr 12 to Apr 13
₩554,902
₩656,311 total
Apr 12 - Apr 13
includes taxes & fees
9.2/10 Wonderful! (1,710 reviews)
Awesome location. I’d really have to nitpick to write anything negative about the place.

Reviewed on Mar 22, 2026

Sanibel Island Beach Resort
See all 13,724 properties in Fort Myers River District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Fort Myers River District vacation package cost?
Perhaps less than you imagined — from a low , actually! By combining hotels, flights and car rentals into a tailor-made vacation package, your trip to Fort Myers River District is just clicks away.
How do I get a cheap travel package to Fort Myers River District?
Combine your flight and hotel bookings, add extras such as activities or a rental car, and save with a Fort Myers River District vacation package. You won't just walk away with exciting discounts on your adventure — you'll have a world of choice too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 properties around the world. Your affordable vacation starts right here, right now!
How far in advance should I book my Fort Myers River District vacation?
Be rewarded with the widest variety and the lowest prices by booking your trip to Fort Myers River District early. Airlines usually sell flights around 12 months in advance, so start your planning as soon as possible. Having said that, Expedia is constantly working to give you the best bargains around, so there's never a bad time to book your dream vacation!
What does an Expedia Fort Myers River District travel package include?
Car rentals, flights and hotels — we connect you to the very best deals. All you'll have to do is figure out your preferred combination. After you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it simple to create an amazing Fort Myers River District vacation.
What should I know before booking a Fort Myers River District travel package?
Our prices are always low. However, you'll enjoy an even better deal when you book your flights, hotels and car rentals together. With an Expedia package, you'll always get transparent pricing and loads of choice.
Can I choose my airline with a Fort Myers River District Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just choose the carrier that suits you and put together your ideal Fort Myers River District getaway.
If I'm not able to travel, can I cancel my Fort Myers River District vacation package?
If your vacation plans in Fort Myers River District have changed, it's comforting to know that it's possible to cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may charge a fee. For more information, check our Customer Service Portal.

Discover the most popular places to visit in Fort Myers River District

Edison and Ford Winter Estates which includes a house and street scenes

Edison and Ford Winter Estates

Explore the winter estates of two of the most famous men in American history. Tour their houses and gardens and learn more about their lives in the museum.

Edison and Ford Winter Estates
Port Sanibel Marina featuring a bay or harbor

Port Sanibel Marina

Explore the waterfront in Fort Myers with a trip to Port Sanibel Marina. Stroll along the beautiful beaches or discover the beautiful sunrises in this family-friendly area.

Port Sanibel Marina

Gulf Coast Town Center

You can search for that perfect souvenir at Gulf Coast Town Center during your trip to Fort Myers. Attend a baseball game or simply enjoy the lively bars while you're in the area.

Gulf Coast Town Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.