Fort Myers River District Vacations

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Where to stay in Fort Myers River District

Find the best Fort Myers River District areas and neighborhoods for the activities you enjoy most. Learn more about Fort Myers River District
Aerial view of the road bridge between Captiva Island and Sanibel Island in Lee County, Florida, United States

Iona

While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.

Find hotels in Iona

Fort Myers River District Hotel Deals

Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

3 out of 5
2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩166,449 per night from Jul 2 to Jul 3
₩166,449
₩185,590 total
Jul 2 - Jul 3
includes taxes & fees
9.2/10 Wonderful! (985 reviews)
"Cleaning was not every day and a couple of times asked for it to be made up but it never happened. Gym room was a little warm. But it was a great hotel in walking distance to downtown Fort Myers, and was great other than those couple of minor points. But it’s a great location to explore south west ..."

Reviewed on May 30, 2026

Hampton Inn Fort Myers Downtown
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩100,641 per night from Jun 27 to Jun 28
₩100,641
₩112,214 total
Jun 27 - Jun 28
includes taxes & fees
6.8/10 (1,098 reviews)
"Clean environment/ staff and all the good shops near by"

Reviewed on May 31, 2026

Baymont by Wyndham Fort Myers Central
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩361,648 per night from Jun 16 to Jun 17
₩361,648
₩456,199 total
Jun 16 - Jun 17
includes taxes & fees
8.6/10 Excellent! (1,009 reviews)
"We had an amazing stay that started and continued with the Valet Staff, the Front Desk Staff, the Restaurant Staff and the Housekeeping Staff. Great associates that want your stay to be the best! Loved the views from our room of the water and the sunsets. We saw dolphins each night. Thanks for a ..."

Reviewed on Jun 1, 2026

Marriott Sanibel Harbour Resort & Spa
See all 13,766 properties in Fort Myers River District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Fort Myers River District vacation package cost?
Perhaps less than you imagined — from a low , actually! By combining hotels, flights and car rentals into a tailor-made vacation package, your trip to Fort Myers River District is just clicks away.
How do I get a cheap travel package to Fort Myers River District?
Combine your flight and hotel bookings, add extras such as activities or a rental car, and save with a Fort Myers River District vacation package. You won't just walk away with exciting discounts on your adventure — you'll have a world of choice too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 properties around the world. Your affordable vacation starts right here, right now!
How far in advance should I book my Fort Myers River District vacation?
Be rewarded with the widest variety and the lowest prices by booking your trip to Fort Myers River District early. Airlines usually sell flights around 12 months in advance, so start your planning as soon as possible. Having said that, Expedia is constantly working to give you the best bargains around, so there's never a bad time to book your dream vacation!
What does an Expedia Fort Myers River District travel package include?
Car rentals, flights and hotels — we connect you to the very best deals. All you'll have to do is figure out your preferred combination. After you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it simple to create an amazing Fort Myers River District vacation.
What should I know before booking a Fort Myers River District travel package?
Our prices are always low. However, you'll enjoy an even better deal when you book your flights, hotels and car rentals together. With an Expedia package, you'll always get transparent pricing and loads of choice.
Can I choose my airline with a Fort Myers River District Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just choose the carrier that suits you and put together your ideal Fort Myers River District getaway.
If I'm not able to travel, can I cancel my Fort Myers River District vacation package?
If your vacation plans in Fort Myers River District have changed, it's comforting to know that it's possible to cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may charge a fee. For more information, check our Customer Service Portal.

Discover the most popular places to visit in Fort Myers River District

Edison and Ford Winter Estates

Edison and Ford Winter Estates

Explore the winter estates of two of the most famous men in American history. Tour their houses and gardens and learn more about their lives in the museum.

Edison and Ford Winter Estates
Port Sanibel Marina

Port Sanibel Marina

Explore the waterfront in Fort Myers with a trip to Port Sanibel Marina. Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.

Port Sanibel Marina
Six Mile Cypress Slough Preserve

Six Mile Cypress Slough Preserve

From the comfort of elevated boardwalks, walk among the turtles, otters, alligators and other creatures that call this wetlands home.

Six Mile Cypress Slough Preserve
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.