Fort Myers River District Vacations

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Where to stay in Fort Myers River District

Find the best Fort Myers River District areas and neighborhoods for the activities you enjoy most. Learn more about Fort Myers River District
Aerial view of the road bridge between Captiva Island and Sanibel Island in Lee County, Florida, United States

Iona

While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.

Find hotels in Iona

Fort Myers River District Hotel Deals

Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

3 out of 5
2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩170,097 per night from Jun 15 to Jun 16
₩170,097
₩189,657 total
Jun 15 - Jun 16
includes taxes & fees
9.2/10 Wonderful! (976 reviews)
Staff was Always Friendly, daily Breakfast was so good with an array to choose from, plenty of parking and rooms were clean!!! What more could you ask for! We will definitely be coming back!

Reviewed on May 9, 2026

Hampton Inn Fort Myers Downtown
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩77,296 per night from Jun 2 to Jun 3
₩77,296
₩86,190 total
Jun 2 - Jun 3
includes taxes & fees
6.8/10 (1,074 reviews)
Do not book this hotel.. i need to be shut down. The area is dirty the room smells like mold. The furnitures are old and rotten. Lots of weed smoking on the compound and i had a flight to catch the following day, i had to keep spray my luggage. This hotel is very tacky and need alot of maintenance. ...

Reviewed on May 14, 2026

Baymont by Wyndham Fort Myers Central
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ₩334,404 per night from Jun 2 to Jun 3
₩334,404
₩447,739 total
Jun 2 - Jun 3
includes taxes & fees
9/10 Wonderful! (2,103 reviews)
Very loud music and shouting late into the night. And we were on the 4th floor, away from the beach.

Reviewed on May 15, 2026

Margaritaville Beach Resort Fort Myers
See all 13,730 properties in Fort Myers River District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Fort Myers River District vacation package cost?
Perhaps less than you imagined — from a low , actually! By combining hotels, flights and car rentals into a tailor-made vacation package, your trip to Fort Myers River District is just clicks away.
How do I get a cheap travel package to Fort Myers River District?
Combine your flight and hotel bookings, add extras such as activities or a rental car, and save with a Fort Myers River District vacation package. You won't just walk away with exciting discounts on your adventure — you'll have a world of choice too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 properties around the world. Your affordable vacation starts right here, right now!
How far in advance should I book my Fort Myers River District vacation?
Be rewarded with the widest variety and the lowest prices by booking your trip to Fort Myers River District early. Airlines usually sell flights around 12 months in advance, so start your planning as soon as possible. Having said that, Expedia is constantly working to give you the best bargains around, so there's never a bad time to book your dream vacation!
What does an Expedia Fort Myers River District travel package include?
Car rentals, flights and hotels — we connect you to the very best deals. All you'll have to do is figure out your preferred combination. After you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it simple to create an amazing Fort Myers River District vacation.
What should I know before booking a Fort Myers River District travel package?
Our prices are always low. However, you'll enjoy an even better deal when you book your flights, hotels and car rentals together. With an Expedia package, you'll always get transparent pricing and loads of choice.
Can I choose my airline with a Fort Myers River District Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just choose the carrier that suits you and put together your ideal Fort Myers River District getaway.
If I'm not able to travel, can I cancel my Fort Myers River District vacation package?
If your vacation plans in Fort Myers River District have changed, it's comforting to know that it's possible to cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may charge a fee. For more information, check our Customer Service Portal.

Discover the most popular places to visit in Fort Myers River District

Edison and Ford Winter Estates

Edison and Ford Winter Estates

Explore the winter estates of two of the most famous men in American history. Tour their houses and gardens and learn more about their lives in the museum.

Edison and Ford Winter Estates
Port Sanibel Marina

Port Sanibel Marina

Explore the waterfront in Fort Myers with a trip to Port Sanibel Marina. Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.

Port Sanibel Marina
Six Mile Cypress Slough Preserve

Six Mile Cypress Slough Preserve

From the comfort of elevated boardwalks, walk among the turtles, otters, alligators and other creatures that call this wetlands home.

Six Mile Cypress Slough Preserve
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.