Santa Maria

Guayaquil

Santa Maria Hotel Deals

Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
The price is ₩157,402 per night from Aug 8 to Aug 9
₩157,402
₩180,580 total
Aug 8 - Aug 9
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (944 reviews)
"well located and safe enviroment"

Reviewed on Jul 17, 2026

Hilton Colon Guayaquil
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
The price is ₩126,457 per night from Aug 8 to Aug 9
₩126,457
₩146,541 total
Aug 8 - Aug 9
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
The price is ₩148,624 per night from Aug 16 to Aug 17
₩148,624
₩170,924 total
Aug 16 - Aug 17
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,001 reviews)
"Nice river view, clean room, nice staff and breakfast buffet great!!!"

Reviewed on Jul 15, 2026

Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
The price is ₩134,684 per night from Aug 7 to Aug 8
₩134,684
₩155,590 total
Aug 7 - Aug 8
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Holiday Inn Guayaquil Airport by IHG
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
The price is ₩106,001 per night from Aug 16 to Aug 17
₩106,001
₩124,039 total
Aug 16 - Aug 17
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9.2/10 Wonderful! (1,001 reviews)
"Muy buen hotel ubicado en el centro de Guayaquil. Exclente desayuno. Muy buena atención."

Reviewed on Jul 17, 2026

Unipark by Oro Verde Hotels
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
The price is ₩119,167 per night from Jul 26 to Jul 27
₩119,167
₩135,547 total
Jul 26 - Jul 27
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
"5 minutes de l’aéroport. Personnel aimable et très atentionné. 2 restaurants dont un situé au roof top. Chambre confortable."

Reviewed on Jul 6, 2026

Wyndham Garden Guayaquil
See all 438 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and El Carmen Hill while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Chocolate Museum while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or World Trade Center.

Santa Maria