Santa Maria Vacations

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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Find hotels in Ecuador

Santa Maria Hotel Deals

Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ₩116,829 per night from May 16 to May 17
₩116,829
₩132,209 total
May 16 - May 17
9.6/10 Exceptional! (1,004 reviews)
Great service great location

Reviewed on May 3, 2026

Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ₩147,737 per night from May 16 to May 17
₩147,737
₩166,208 total
May 16 - May 17
9.2/10 Wonderful! (1,001 reviews)
Clean room

Reviewed on Apr 20, 2026

Wyndham Guayaquil Puerto Santa Ana
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ₩96,125 per night from May 9 to May 10
₩96,125
₩109,435 total
May 9 - May 10
9.2/10 Wonderful! (1,001 reviews)
Great place for a long overnight stay.

Reviewed on Apr 30, 2026

Unipark by Oro Verde Hotels
See all 430 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Maria vacation package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting . When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1,000,000 hotels worldwide, your Santa Maria vacation package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream vacation in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favorites.
How far in advance should I book my Santa Maria vacation?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your vacation time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia vacation package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria vacation package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.

Discover the most popular places to visit in Santa Maria

The river front of Guayaquil

City Mall

4.5/5(48 reviews)

During your visit to Guayaquil, you can do some window-shopping at City Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.

City Mall

San Marino Mall

4.5/5(56 reviews)

During your visit to Guayaquil, you can find the perfect gifts to bring home at San Marino Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.

San Marino Mall

Mall del Sur

You can enjoy retail therapy at Mall del Sur during your visit to Guayaquil. While in this walkable area, find time to visit its shops.

Mall del Sur
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.