Santa Maria Vacations
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Where to stay in Santa Maria
Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
Ecuador
Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.
Downtown Guayaquil
Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Moorish Clock Tower while you're in town.
Puerto Santa Ana
Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.
Kennedy
1 out of top 10 points of interest in this area
Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.
Urdesa
Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Alban Borja Commercial Center.
Santa Maria Hotel Deals
Oro Verde Guayaquil
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
₩127,903
₩144,059 total
Sep 18 - Sep 19
9.6/10 Exceptional! (1,000 reviews)
"Very modern property. Felt extremely safe staying here for 1 night between flights. Had a wonderful refreshing cocktail and dinner at the restaurant. Breakfast was excellent with a huge variety of dishes. Having a complimentary shuttle to and from the airport was a huge plus point, as didn’t need ..."
Reviewed on Sep 15, 2026
Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
₩155,100
₩173,976 total
Sep 27 - Sep 28
9.4/10 Exceptional! (1,005 reviews)
"No me gustó que ese día hubo un evento en el hotel , y la música se escuchaba en la habitación , a tal punto que fue imposible dormir con tanto ruido, nada pudieron hacer al respecto , pese a notificarlo. Dada la hora (11 pm) y que viajaba con niños , tampoco consideré trasladarme ese momento a otro ..."
Reviewed on Sep 14, 2026
Holiday Inn Guayaquil Airport by IHG
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
₩126,765
₩142,849 total
Oct 17 - Oct 18
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Maria vacation package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting . When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1,000,000 hotels worldwide, your Santa Maria vacation package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream vacation in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favorites.
How far in advance should I book my Santa Maria vacation?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your vacation time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia vacation package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria vacation package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.