This place is a gem. If you're coming to Vegas for reasons other than mindlessly walking the strip, or you don't like the hassle and noise of the giant hotels, Desert Rose is for you.
I stayed here to access a conference at the Mandalay Bay conference center and it was the greatest. Nice cosy pool that isn't crowded, and the staff were all great, especially Michaela at the bar.
Rooms are spacious and kitchenettes have everything you need. 15 minute walk to Mandalay or Luxor/Excaliber.
Other reviews complained about noise but I did not experience it at all. I was in the center in Building 1 and was not disturbed by any noises.
The only odd thing is the "welcome desk" that they send you to after check-in. For sure this is some kind of experience/timeshare kind of thing, but as a single business traveller they only asked me a couple questions and then handed me an entertainment guidebook and didn't try to sell me anything.
Will definitely be staying here again in the future.