South Central Houston, TX
Houston





Visit South Central Houston
Popular places to visit

Rice University
Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's acclaimed theater scene and lively festivals.

University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the lively festivals and acclaimed theater scene in this vibrant area.

Houston Zoo
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.

Houston Natural Science Museum
You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's acclaimed theater scene and lively festivals.

Main Street Theater - Rice Village
You can enjoy a show at Main Street Theater - Rice Village during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's lively festivals and acclaimed art scene.
South Central Houston Hotel Deals

Hilton Houston Plaza/Medical Center
The property was wonderful, but the staff was Exemplary. I spent about 10-12 days here on different reservations and Seymour, at the front desk, was very helpful and attentive to all of my needs. Thank you Seymour!
Reviewed on Jan 5, 2026

Downtowner Inns - Houston Downtown
Room was nice, clean and close to midtown
Reviewed on Dec 26, 2025

Hotel Zaza Houston Museum District
Everything was nice except the pillows, if you can even call them that. Pillows should be trashed.
Reviewed on Jan 2, 2026

The Westin Houston Medical Center/Museum District
Great place to stay with family! Super comfortable and clean. Lots of amenities in and near hotel.
Reviewed on Jan 5, 2026

InterContinental Houston by IHG
Totally enjoyed our room and stay. And thoroughly enjoyed our dinner at the Safina. We highly recommend the InterContinental Houston.
Reviewed on Jan 7, 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Only negative was at dinner the staff was overwhelmed by the amount of clientele
Reviewed on Jan 1, 2026
Other neighborhoods around South Central Houston

Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.

Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
