Top South Central Houston Hotels

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Property	Property class	Guest rating
La Maison in Midtown an urban B&B	3.5 star property	9.8 Exceptional 575 reviews	View
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only	3.5 star property	9.6 Exceptional 214 reviews	View
Downtowner Inns - Houston Downtown	2.0 star property	9.2 Wonderful 160 reviews	View
Hotel Zaza Houston Museum District	4.5 star property	9.2 Wonderful 1,018 reviews	View
InterContinental Houston by IHG	4.0 star property	9.2 Wonderful 1,018 reviews	View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

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The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

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Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

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Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.

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Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

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Top South Central Houston Hotel Reviews

Hotel Zaza Houston Museum District

10/10 Excellent

"We really enjoyed our stay! Room was very clean and staff super friendly and helpful."

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2/10 Terrible

"We had two rooms in the 3 days we were there. Both rooms were disgusting. The worst was room 341. The walls were dirty. We could not use the couch or chairs because they were so dirty. The bathtub leaked and got the floor soaked. The caulking job was terrible. The bathtub felt like you could fall through it. The air unit kicked on in the middle of the night and woke us up because it smelt like nasty burnt pee. They did not come clean our room when I asked that they do at the front desk. The only thing available for breakfast was coffee, hot water and a basket of cereal bars. Being a hockey family we have been in many hotels and I have never experienced such uncleanliness. The staff was friendly and apologized but gave the excuse that they are an extended stay and only clean their rooms every 14 days! What?? Not acceptable."

The Westin Houston Medical Center/Museum District

10/10 Excellent

"The room was very clean somewhat there was hai inside the bathtub so I wasn’t able to use it. Air conditioner didn’t get cold it took 1 hour before we feel the coldness. It was hard to find the parking we found the easiest parking valet when we were about to leave. But overall it was very neat and close to everything. I will stay longer so I can actually enjoy the amenities and we didn’t have a chance to check out the bar and the breakfast."

Frequently asked questions

What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out Fertitta Center and Continental Club as part of your South Central Houston travel plans.

What's the best accommodation in South Central Houston?

Based on our traveler data, Hilton Houston Plaza/Medical Center is one of the top choices for your stay in South Central Houston. This hotel is a short 9-minute walk from MD Anderson Cancer Center, and it offers 2 restaurants and 2 bars. Other good options for your stay in the area include Hotel Zaza Houston Museum District and InterContinental Houston by IHG.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1193 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape, and Cullen Sculpture Garden. Fertitta Center and Continental Club are some other stops to visit in the neighborhood. Don't miss favorite places to visit in the surrounding area, such as Toyota Center, Daikin Park, and Downtown Aquarium. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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Our top choices for South Central Houston hotels

Downtowner Inns - Houston Downtown

Sentral Forme Houston

The Westin Houston Medical Center/Museum District

Hilton Houston Plaza/Medical Center

Hotel Zaza Houston Museum District

Houston Marriott Medical Center/Museum District

InterContinental Houston by IHG

La Maison in Midtown an urban B&B

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn Medical Center Downtown

Golden Motel Near Houston Medical Center

2-bedroom - Equipped Kitchen - Gated Parking

Hilton University of Houston

Southmore Boulevard Motel

Cozy 2BR Near NRG & Downtown FIFA World Cup

Extended Stay America Suites Houston Med Ctr Braeswood Bl

MorningSide Inn

Luxury Med Center Fully Equipped King Sized Bed Condos

Wanderstay Houston Hostel

Compare popular hotels in South Central Houston

Where to stay in South Central Houston

Downtown Houston

The Galleria

Texas Medical Center

Montrose

Houston Central Business District

Top South Central Houston Hotel Reviews

Hotel Zaza Houston Museum District

Frequently asked questions

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