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Discover 1,151 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Days Inn & Suites by Wyndham Downtown/University of Houston
Exterior

Days Inn & Suites by Wyndham Downtown/University of Houston

2.0 star property
8.0 out of 10, Very Good, (720)
"Great Stay for the cost"
The price is ₩81,457
₩95,306 total
includes taxes & fees
Sep 14 - Sep 15
Days Inn & Suites by Wyndham Downtown/University of Houston
Americas Best Value Inn NRG Park Medical Center
Free self parking

Americas Best Value Inn NRG Park Medical Center

2.0 star property
7.8 out of 10, Good, (778)
"The beds were awesome and very clean rooms. "
The price is ₩88,539
₩103,591 total
includes taxes & fees
Sep 13 - Sep 14
Americas Best Value Inn NRG Park Medical Center
Holiday Inn Express & Suites Houston – Downtown North by IHG
Exterior

Holiday Inn Express & Suites Houston – Downtown North by IHG

2.5 star property
9.2 out of 10, Wonderful, (570)
"The hotel is very clean and the staff is super friendly and helpful."
The price is ₩148,608
₩173,871 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express & Suites Houston – Downtown North by IHG
Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillowtop beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1770)
"I loved this hotel. I loved the staff’s hospitality."
The price is ₩306,285
₩416,060 total
includes taxes & fees
Sep 14 - Sep 15
Hotel Zaza Houston Museum District
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
8.0 out of 10, Very Good, (999)
"Good location "
The price is ₩97,984
₩114,640 total
includes taxes & fees
Sep 18 - Sep 19
Americas Best Value Inn Medical Center Downtown
Hilton Houston Plaza/Medical Center
Sundeck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very Good, (1571)
"Bed was great ..slept so well..nice and friendly staff "
The price is ₩137,497
₩162,483 total
includes taxes & fees
Sep 14 - Sep 15
Hilton Houston Plaza/Medical Center
La Maison in Midtown an urban B&B
Exterior

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (519)
"Nice property we are enjoying our stay. "
The price is ₩248,606
₩290,868 total
includes taxes & fees
Sep 15 - Sep 16
La Maison in Midtown an urban B&B
Wanderstay Boutique Hotel
Double Room, 1 Queen Bed with Sofa bed | In-room safe, individually decorated, individually furnished, desk

Wanderstay Boutique Hotel

2.0 star property
10.0 out of 10, Exceptional, (43)
"Great stay!"
The price is ₩179,996
₩210,596 total
includes taxes & fees
Sep 14 - Sep 15
Wanderstay Boutique Hotel
Houston Marriott Medical Center/Museum District
Lobby

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1001)
"Enjoyed the stay"
The price is ₩234,926
₩319,771 total
includes taxes & fees
Oct 10 - Oct 11
Houston Marriott Medical Center/Museum District
InterContinental Houston by IHG
Reception

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1004)
"Very friendly staff!"
The price is ₩198,607
₩260,147 total
includes taxes & fees
Sep 19 - Sep 20
InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Great place to stay. "
The price is ₩249,370
₩310,392 total
includes taxes & fees
Sep 14 - Sep 15
The Westin Houston Medical Center/Museum District
Downtowner Inns - Houston Downtown
Exterior

Downtowner Inns - Houston Downtown

2.0 star property
The price is ₩124,997
₩146,247 total
includes taxes & fees
Sep 13 - Sep 14
Downtowner Inns - Houston Downtown
Hilton University of Houston
1 bedroom, premium bedding, down comforters, pillowtop beds

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (859)
"Perfect for new students and families."
The price is ₩223,120
₩261,050 total
includes taxes & fees
Sep 18 - Sep 19
Hilton University of Houston
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.2 out of 10, Very Good, (421)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is ₩183,941
₩215,212 total
includes taxes & fees
Sep 19 - Sep 20
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
The price is ₩287,494
₩357,201 total
includes taxes & fees
Sep 15 - Sep 16
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Modern Cozy Home with King Bed
Comfort Townhome | Private kitchen | Full-size fridge, microwave, oven, dishwasher

Modern Cozy Home with King Bed

3.5 star property
9.4 out of 10, Exceptional, (20)
"Very spacious and close to just about everything. The view is amazing too"
The price is ₩187,496
₩483,253 total
includes taxes & fees
Sep 16 - Sep 17
Modern Cozy Home with King Bed
Luxurious 3 Bed3 Bath Near Downtown Houston
House | 3 bedrooms, Internet

Luxurious 3 Bed3 Bath Near Downtown Houston

2.0 star property
10.0 out of 10, Exceptional, (1)
"This was made for a perfect family vacation… super clean kid friendly with an awesome view of Houston for the adults on rooftop "
The price is ₩195,426
₩544,542 total
includes taxes & fees
Sep 15 - Sep 16
Luxurious 3 Bed3 Bath Near Downtown Houston
Paradise Palace Best Rooftop in HTX w Hot Tub
House | 4 bedrooms, desk, iron/ironing board, Internet

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
The price is ₩429,953
₩897,912 total
includes taxes & fees
Sep 16 - Sep 17
Paradise Palace Best Rooftop in HTX w Hot Tub
Posh Dtwn Midtown Home w Stunning Roof-topterrace
House | 4 bedrooms, soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
The price is ₩322,226
₩894,720 total
includes taxes & fees
Sep 23 - Sep 24
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
House, 3 Bedrooms | Private kitchen | Fridge, oven, coffee/tea maker, electric kettle

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is ₩293,438
₩814,566 total
includes taxes & fees
Sep 13 - Sep 14
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

2 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Houston featuring a city and a high rise building

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Top South Central Houston Hotel Reviews

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel

10/10 Excellent
"This hotel is super cute and I would definitely stay again "
Seivauje 1-night trip
Posted 3 days ago
Wanderstay Boutique Hotel

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other favorite options in the area include The Westin Houston Medical Center/Museum District and MyCrib Houston Hostel.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1140 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Houston Zoo and Continental Club are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.