South Central Houston Vacations

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Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

South Central Houston Hotel Deals

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is ₩130,409 per night from Oct 12 to Oct 13
₩130,409
₩154,215 total
Oct 12 - Oct 13
includes taxes & fees
8.2/10 Very Good! (1,608 reviews)
"My daughter was having a very early procedure at the hospital and the convenience of the hospital was awesome. The grill and bar area was friendly and the food was good."

Reviewed on Sep 24, 2025

Hilton Houston Plaza/Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
The price is ₩381,689 per night from Sep 27 to Sep 28
₩381,689
₩507,209 total
Sep 27 - Sep 28
includes taxes & fees
8.8/10 Excellent! (1,779 reviews)
"Terrific customer service! We enjoyed the restaurant and the 3-mile car service. You can’t beat the location."

Reviewed on Sep 22, 2025

Hotel Zaza Houston Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St, Houston, TX
Fully refundable
The price is ₩218,377 per night from Oct 5 to Oct 6
₩218,377
₩283,681 total
Oct 5 - Oct 6
includes taxes & fees
9.2/10 Wonderful! (1,019 reviews)
"Very nice hotel, workers very friendly. Food good. I will return to this hotel."

Reviewed on Sep 20, 2025

InterContinental Houston by IHG
See all 1,155 properties in South Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a South Central Houston vacation package cost?
Starting from a low , a vacation package is your passport to inexpensive travel. Custom build your South Central Houston getaway by selecting from our huge range of hotels, flights and rental cars.
How do I get a cheap travel package to South Central Houston?
Combining your flight and hotel with Expedia won't just save you time — it'll save you a tidy sum too. A South Central Houston vacation package makes it easy to put together the perfect trip. With more than 550 airlines across the world to choose from, finding flights that suit your busy schedule won't be a problem. On top of that, we have over 1,000,000 hotels globally to select from. Now that's what we call choice. Whatever your budget, Expedia will help show you the world.
How far in advance should I book my South Central Houston vacation?
While not all air carriers release ticket prices early, you can usually compare international fares on Expedia up to 12 months in advance. This is the time you can nab some incredible deals. If you've left everything to the last minute, you might get lucky. Low prices sometimes appear just weeks before departure.
What does an Expedia South Central Houston travel package include?
That depends on what you're after. If you're traveling by yourself, you might decide to bundle hotels and flights. Taking the whole family to South Central Houston? A travel package including hotels, flights and rental cars might suit you better. Expedia gives you the flexibility to build your own travel package.
What should I know before booking a South Central Houston travel package?
Design deals that suit your budget with an Expedia package. Flights, hotels, rental cars — we have everything you need to plan your escape. You'll save a packet just by combining your bookings. Whether you're embarking on a ski trip or drinking cocktails on a beach, your dream vacation is just a few clicks away.
Can I choose my airline with a South Central Houston Expedia vacation package?
Yes, you sure can. We offer more than 550 airline partners worldwide, so select the carrier that matches your budget needs.
If I'm not able to travel, can I cancel my South Central Houston vacation package?
Yes, it's possible to cancel your South Central Houston booking if your travel plans have been upended. Whether you'll incur a penalty or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking free of charge if you booked in the last 24 hours. Head to our Customer Service Portal to find out more.

Discover the most popular places to visit in South Central Houston

Rice University

Rice University

4.5/5(356 reviews)

Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed theater scene and lively festivals.

Rice University
Houston Zoo

Houston Zoo

4.5/5(998 reviews)

Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.

Houston Zoo
Houston Natural Science Museum featuring heritage elements and interior views

Houston Natural Science Museum

4.5/5(805 reviews)

You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's great live music and acclaimed theater scene.

Houston Natural Science Museum
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.