South Central Houston, TX

Houston

A water feature with multiple tiers and a circular viewing platform at the top.
A city skyline at night with illuminated skyscrapers and a large brick plaza in the foreground.
A train on tracks with graffiti on a nearby building.
A park with a gazebo, a fountain, and tall buildings in the background.
A water feature with a cascading waterfall, a grassy hill, and a tall building in the background.

Stay near popular South Central Houston attractions

A large historic building with a red roof and arched windows, surrounded by a well-maintained garden and a clear blue sky.

Rice University

8.6/5 (1,772 reviews)
Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's fascinating museums and acclaimed art scene.
See properties

South Central Houston Hotel Deals

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is ₩355,468 per night from Jul 7 to Jul 8
₩355,468
₩486,829 total
Jul 7 - Jul 8
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,002 reviews)
"Beware! I was charged additional fees for room service. $50 tip that wasn’t authorized along with double dipping charges multiple charges that make no sense! Memorial city location is Fabulous! Not this location"

Reviewed on Jun 27, 2026

Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is ₩197,985 per night from Jul 5 to Jul 6
₩197,985
₩233,422 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,977 reviews)
"It was everything I expected.. loved the room so big and clean"

Reviewed on Jun 28, 2026

Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is ₩233,285 per night from Jul 26 to Jul 27
₩233,285
₩303,638 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Excellent hotel. Staff very helpful. Great location. Clean. Best part of the trip was us being surprised that our hotel was a 2026 World Cup host. Fest for the teams was awesome. My son loved getting that close to the team players. Got several autographs."

Reviewed on Jun 27, 2026

InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is ₩219,779 per night from Jul 5 to Jul 6
₩219,779
₩273,560 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,152 reviews)
"Clean, modern room. Helpful and available staff. A+++"

Reviewed on Jun 25, 2026

The Westin Houston Medical Center/Museum District
Sentral Forme Houston

Sentral Forme Houston

4.5 out of 5
5501 La Branch Street Houston TX
The price is ₩259,376 per night from Jul 7 to Jul 8
₩259,376
₩348,362 total
Jul 7 - Jul 8
includes taxes & fees
Book a stay at this luxury aparthotel in Houston. Enjoy a 24-hour fitness center, parking (surcharge), and a 24-hour front desk. Popular attractions Toyota Center ...
8.8/10 Excellent! (59 reviews)
"Felt like home away from home & staff was very accommodating and kind. 10/10"

Reviewed on Jun 28, 2026

Sentral Forme Houston
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
The price is ₩124,301 per night from Jul 8 to Jul 9
₩124,301
₩145,865 total
Jul 8 - Jul 9
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
5.8/10 (1,006 reviews)
"The room was filthy, the fridge had three brown stains on the side, dead flys everywhere and the drawers had dead mosquitoes. There was an intense moldy smell. I only stayed one night and even that was too long a stay."

Reviewed on Jun 27, 2026

Extended Stay America Suites Houston Med Ctr Braeswood Bl
See all 1,234 properties in South Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
A cityscape with modern skyscrapers and a park with trees and people.

Downtown Houston

Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Toyota Center and Daikin Park are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.

A large, modern shopping mall with a glass ceiling and multiple levels.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

A cityscape with tall buildings, including a prominent one with 'Texas Children's Hospital' on it, under a partly cloudy sky.

Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

An art gallery with a minimalist design, featuring a central bench and large abstract paintings on the walls.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

South Central Houston, TX