South Central Houston, TX
Houston





Visit South Central Houston
South Central Houston Hotel Deals

Hilton Houston Plaza/Medical Center
The hotel was great and convenient. Easy check in an check out. Will definitely stay again.
Reviewed on Dec 22, 2025

Hotel Zaza Houston Museum District
Staff was great, hotel is beautiful. Valet parking is ridiculously expensive.
Reviewed on Dec 21, 2025

Downtowner Inns - Houston Downtown
Check in staff was friendly and room was clean.
Reviewed on Dec 14, 2025

The Westin Houston Medical Center/Museum District
Service
Reviewed on Dec 20, 2025

InterContinental Houston by IHG
Clean quick check in
Reviewed on Dec 19, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Room is very clean and nice. Lovely staff!
Reviewed on Dec 22, 2025
Other neighborhoods around South Central Houston

Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.

Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
