Isola Vacation Rentals

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Check prices for these dates

In two weeks
Jan 16 - Jan 18
In two months
Feb 27 - Mar 1
In three months
Mar 27 - Mar 29
In four months
Apr 24 - Apr 26

Our top choices for Isola vacation rentals

Terrace/patio
Alla Giudecca

Residence in Ortigia

Alla Giudecca
3.0 star property
8.4 out of 10, Very Good, (273)
"We loved the history of the building, it was beautiful. Spacious rooms with outside sitting area. Walkable to all areas of interest in Ortigia and cafes and restaurants. Staff were helpful. "
United Kingdom
Carol
Alla Giudecca
Beach shuttle
Terra Mia Affittacamere

Townhouse in Melilli

Terra Mia Affittacamere
3.0 star property
9.4 out of 10, Exceptional, (20)
"Lovely location and great family business. Antonio was a perfect host and made me feel like part of the family. Home cooked fresh food and cold beers was great after a long day ! Clean tidy room and great price. Highly recommended ! "
United States
KEIRON
The price is ₩107,098
₩117,807 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Terra Mia Affittacamere
Deluxe Double or Twin Room (101) | Terrace/patio
Thalya Luxury Rooms

Townhouse in Syracuse

Thalya Luxury Rooms
3.0 star property
9.0 out of 10, Wonderful, (42)
"Wonderful stay!"
United States
Kristie
Thalya Luxury Rooms
Exterior
Hotel Morfeo Residence

Residence in Syracuse

Hotel Morfeo Residence
3.0 star property
7.4 out of 10, Good, (26)
"The hotel is conveniently located. Everything is walkable. The hotel is quiet. The beds are however awful. Very very hard beds. The kitchen was not well stocked but had basics. "
United States
Gregory Allan
Hotel Morfeo Residence
Terrace/patio
Populus

Townhouse in Santa Lucia

Populus
1.0 star property
7.8 out of 10, Good, (74)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ₩123,927
₩141,285 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Populus
Ballroom
Il Giardino del Barocco

Townhouse in Noto

Il Giardino del Barocco
3.0 star property
9.2 out of 10, Wonderful, (113)
"This is a place to as it's real close to the historic center, cozy rooms in a beautiful garden and with different options for breakfast, "
United States
Edwin
Il Giardino del Barocco
Front of property
Byssus Suites

Aparthotel in Syracuse

Byssus Suites
9.8 out of 10, Exceptional, (35)
"Very nice hotel with spacious, comfortable rooms and friendly staff. The recommendations for the restaurants and activities in the area were useful and nice. The breakfast buffet had a nice variety of options and all products were super fresh. Highly recommend this hotel!"
Netherlands
Annelisa
The price is ₩330,467
₩376,731 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Byssus Suites
City view from property
Aretusa Vacanze B&B

Aparthotel in Ortigia

Aretusa Vacanze B&B
1.0 star property
9.6 out of 10, Exceptional, (299)
"Very well run hotel with attentive and attentive staff. "
Canada
Caroline
The price is ₩131,444
₩149,847 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Aretusa Vacanze B&B
Balcony
Nuova Mastrarua Rooms

Townhouse in Ortigia

Nuova Mastrarua Rooms
8.2 out of 10, Very Good, (32)
"This place was an excellent choice - good location to explore Ortiga, the staff was extremely friendly, the hotel is newly renovated, rooms very clean. Definitely recommended. "
Germany
Marvin
The price is ₩138,362
₩157,728 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Nuova Mastrarua Rooms
Sundeck
Hotel Residence Capo Campolato

Residence in Augusta

Hotel Residence Capo Campolato
4.0 star property
8.8 out of 10, Excellent, (86)
"Great place would stay there again "
United States
Demoin
Hotel Residence Capo Campolato
View from room
1743 Loft Siracusa

Residence in Ortigia

1743 Loft Siracusa
1.0 star property
9.0 out of 10, Wonderful, (52)
"We had an amazing time, the owner was so lovely to deal with and the accommodations are so stunning! "
Canada
Laura
The price is ₩138,362
₩201,697 total
includes taxes & fees
Jan 1 - Jan 2, 2026
1743 Loft Siracusa
Comfort Apartment | Balcony
Matteotti Luxury Residence

Apartment in Ortigia

Matteotti Luxury Residence
9.8 out of 10, Exceptional, (8)
"Property was clean, safe, and modern. Very efficient check in and out and staff communication was timely and informative. Great place to stay!"
Canada
Andrea
Matteotti Luxury Residence
Deluxe Double Room | Memory foam beds, minibar, desk, blackout drapes
Olivia Rooms Teocrito

Townhouse in Neapolis

Olivia Rooms Teocrito
3.0 star property
8.0 out of 10, Very Good, (20)
"Easy to walk to main attraction"
United Kingdom
John W
Olivia Rooms Teocrito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isola Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Every aspect of our stay was superb. The staff were friendly and helpfull. Our room was spotless, and the decor of the entire hotel was harmonious. "
Thomas 2-night trip
Posted 7 days ago
Grand Hotel Ortigia Siracusa

Find out more about Isola

Search for Vacation rentals in Isola on Expedia.co.uk! You can easily find your home rentals, villas, Vacation apartments in Isola using one of the methods below:

  • View our selection of featured Vacation rentals in Isola
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  • Enter your travel dates to view the best deals on Vacation rentals in Isola while they last

Look no further and take a look at our great range of rental properties in Isola!

Frequently asked questions

Can I find a vacation rental in Isola?

Yes, you can find vacation rentals near the most popular sights in Isola, or you can choose a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental in Isola?

Agriturismo Eloro Pizzuta: This vacation home rental outside Isola is located near the beach and has a terrace, a private yard, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave.

How many vacation rentals will I find in Isola?

Choose from 4 Expedia vacation rentals in Isola for a memorable vacation.

What can I see and do in Isola?

Ionian Sea and Spiaggia Punta del Pero are a couple of lovely local spots to get outside and enjoy nature. Fonte Aretusa and Tropical Aquarium of Syracuse are a couple of places you'll find in the larger area.

What are vacation rentals like in Isola?

Vacation rentals are private accommodations you can reserve for a short or long stay in Isola. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you want. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for families.