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Oct 11 - Oct 12
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Our top choices for Lake Issaqueena hotels

A white, two-story house with a front porch, surrounded by trees and shrubs.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.
A bedroom with two beds, a TV, and a fireplace.
A two-story building with a white exterior, a front door, and a balcony.

1. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
13 km from Lake Issaqueena
United States
Christine
₩151,262
₩167,908 total
includes taxes & fees
Oct 30 - Oct 31
Liberty Hall Bed and Breakfast
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.
Private kitchen
A wooden interior with a table, chair, and a hanging lantern.

2. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
15.8 km from Lake Issaqueena
United States
Sebastian
₩124,175
₩195,564 total
includes taxes & fees
Oct 20 - Oct 21
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A golf course with a water body, trees, and a distant view of a bridge.
A golf course with a clubhouse, surrounded by dense trees and a large body of water.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

3. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
8.7 km from Lake Issaqueena
United States
Lilllian
₩199,699
₩221,666 total
includes taxes & fees
Oct 12 - Oct 13
Clemson University's James F. Martin Inn
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

4. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
10.6 km from Lake Issaqueena
United States
Lori
₩160,791
₩176,869 total
includes taxes & fees
Oct 18 - Oct 19
Fairfield Inn & Suites Seneca Clemson Univ Area
A modern bar area with a menu board, bar stools, and a countertop with various items.
An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.
A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.
A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

5. Courtyard Marriott Clemson

Courtyard Marriott Clemson
7.3 km from Lake Issaqueena
United States
kim
₩138,315
₩153,531 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard Marriott Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

6. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
8.6 km from Lake Issaqueena
United States
Lloyd
₩165,227
₩181,751 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Seneca-Clemson Area
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.
A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.
A modern living room with a flat-screen TV, a desk with a chair, an orange sofa, and a framed tiger picture on the wall.
A conference room with a large round table, multiple chairs, and a projector.

7. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
7.1 km from Lake Issaqueena
United States
John
₩172,894
₩191,912 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Clemson by IHG
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A wall with a decorative design featuring a building, trees, and a sky with clouds.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

8. Inn @ Clemson

Inn @ Clemson
6.5 km from Lake Issaqueena
United States
Dan
₩107,355
₩119,163 total
includes taxes & fees
Oct 12 - Oct 13
Inn @ Clemson
Room
A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.
A hotel reception area with two reception desks, a digital screen, and a tiled floor.
A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

9. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
6.6 km from Lake Issaqueena
United States
Yvette
₩141,263
₩156,804 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn & Suites Clemson - University Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.

10. Lakeside Lodge Clemson

Lakeside Lodge Clemson
5.6 km from Lake Issaqueena
United States
Lori
₩146,088
₩181,351 total
includes taxes & fees
Oct 12 - Oct 13
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

11. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
5.8 km from Lake Issaqueena
United States
Melissa
₩141,773
₩155,951 total
includes taxes & fees
Oct 18 - Oct 19
Tru by Hilton Seneca Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.
A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

12. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
6.8 km from Lake Issaqueena
United States
David
₩141,263
₩156,802 total
includes taxes & fees
Oct 13 - Oct 14
Best Western Plus Clemson Hotel & Conference Center
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

13. Quality Inn Seneca US-123

Quality Inn Seneca US-123
13.5 km from Lake Issaqueena
United States
Barry
₩101,324
₩119,522 total
includes taxes & fees
Oct 18 - Oct 19
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

14. Best Western Seneca-Clemson

Best Western Seneca-Clemson
9.7 km from Lake Issaqueena
United States
Michelle
₩135,567
₩149,126 total
includes taxes & fees
Oct 13 - Oct 14
Best Western Seneca-Clemson
A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.
A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".
Private kitchen
A cozy living room with a dining table, sofas, and a chandelier.

15. Clemson Memorabilia House

Clemson Memorabilia House
9.3 km from Lake Issaqueena
United States
Ashley
₩119,283
₩318,366 total
includes taxes & fees
Oct 12 - Oct 13
Clemson Memorabilia House
A modern kitchen area with a bar counter and seating.
A vending area with snacks and beverages, including chips and soda.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.
A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

16. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
5.5 km from Lake Issaqueena
United States
Blaise
₩146,960
₩163,126 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Clemson-University Area
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
An outdoor patio with wicker furniture, a round table, and a fountain.

17. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
6.7 km from Lake Issaqueena
United States
Laurrie
₩280,114
₩310,926 total
includes taxes & fees
Oct 13 - Oct 14
The Shepherd Hotel Downtown Clemson
A swimming pool with lounge chairs and a covered area with tables and chairs.
A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.
A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.
A covered porch with a welcome mat, two black Adirondack chairs, and a bench.

18. Carolina Camp Cedar

Carolina Camp Cedar
20.2 km from Lake Issaqueena
United States
Katlynn
₩146,088
₩273,736 total
includes taxes & fees
Oct 12 - Oct 13
Carolina Camp Cedar
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.
A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.
A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.
A gazebo with a tiled roof and a surrounding gravel area.

19. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
7.1 km from Lake Issaqueena
United States
David
₩107,355
₩119,165 total
includes taxes & fees
Oct 12 - Oct 13
Days Inn by Wyndham Clemson
A kitchen with a coffee maker, microwave, and refrigerator.
A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.
A red brick building with a white porch and columns, a door, and windows.
A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.

20. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
17.7 km from Lake Issaqueena
United States
Richard
₩96,820
₩107,955 total
includes taxes & fees
Nov 9 - Nov 10
Rodeway Inn & Suites Walhalla
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Compare popular hotels close to Lake Issaqueena

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A white, two-story house with a front porch, surrounded by trees and shrubs.
Liberty Hall Bed and Breakfast
9.8
Exceptional
104 reviews
View
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
9.8
Exceptional
111 reviews
View
A golf course with a water body, trees, and a distant view of a bridge.
Clemson University's James F. Martin Inn
9.6
Exceptional
1,002 reviews
View
A poolside area with outdoor seating and a view of a lake and forested hills.
Fairfield Inn & Suites Seneca Clemson Univ Area
9.4
Exceptional
281 reviews
View
A modern bar area with a menu board, bar stools, and a countertop with various items.
Courtyard Marriott Clemson
9.0
Wonderful
587 reviews
View

Hotels recommended for families near Lake Issaqueena

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
₩146,088
₩181,351 total
includes taxes & fees
Oct 12 - Oct 13
Lakeside Lodge Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

The Abernathy of Clemson

The Abernathy of Clemson
Clemson
₩215,916
₩239,668 total
includes taxes & fees
Oct 18 - Oct 19
The Abernathy of Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.
A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
₩141,263
₩156,802 total
includes taxes & fees
Oct 13 - Oct 14
Best Western Plus Clemson Hotel & Conference Center
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
An outdoor patio with wicker furniture, a round table, and a fountain.

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
₩280,114
₩310,926 total
includes taxes & fees
Oct 13 - Oct 14
The Shepherd Hotel Downtown Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
₩141,773
₩155,951 total
includes taxes & fees
Oct 18 - Oct 19
Tru by Hilton Seneca Clemson
Room
A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.
A hotel reception area with two reception desks, a digital screen, and a tiled floor.
A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
₩141,263
₩156,804 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn & Suites Clemson - University Area
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A wall with a decorative design featuring a building, trees, and a sky with clouds.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

Inn @ Clemson

Inn @ Clemson
Clemson
₩107,355
₩119,163 total
includes taxes & fees
Oct 12 - Oct 13
Inn @ Clemson
A modern kitchen area with a bar counter and seating.
A vending area with snacks and beverages, including chips and soda.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.
A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
₩146,960
₩163,126 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Clemson-University Area

Top Lake Issaqueena Hotel Reviews

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"Everything was clean and just what we needed"
irene 1-night trip
Posted 1 day ago
Tru by Hilton Seneca Clemson

Other attractions near Lake Issaqueena

Larry W. Abernathy Waterfront Park

8.6/10 (58 reviews)
Larry W. Abernathy Waterfront Park is just one of the places to see in Clemson, so why not enjoy the other things to explore during your travels? Experience the area's theater scene or attend a football game.
See properties

Littlejohn Coliseum

9.4/10 (141 reviews)
Catch an event at Littlejohn Coliseum during your trip to Clemson. Amble around the area's lakeside or attend a football game.
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Sloan Tennis Center

Catch an event at Sloan Tennis Center during your trip to Clemson. You can attend a football game while in the area.
See properties

Memorial Stadium

9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
See properties

Clemson Area African American Museum

You can spend time browsing the exhibits at Clemson Area African American Museum in Clemson. You can attend a football game while in the area.
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Wyndham Plaza

You can browse for the perfect souvenirs at Wyndham Plaza during your visit to Seneca. Stroll along the lakeside or attend a sporting event in this family-friendly area.
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World of Energy

You can spend an afternoon exploring the galleries in World of Energy in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Lake Issaqueena?
Lake Issaqueena is located in Central. You'll find 209 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Lake Issaqueena?
Lakeside Lodge Clemson is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 3.5 mi (5.6 km) from Lake Issaqueena. Other good choices within a few miles include Best Western Plus Clemson Hotel & Conference Center and Comfort Inn & Suites Clemson - University Area.
How many hotels are there close to Lake Issaqueena?
Expedia has 209 hotels and other accommodations a few miles from Lake Issaqueena.
If I need to cancel the hotel reservation for my stay near Lake Issaqueena, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to review the top deals on offer near Lake Issaqueena.
Where can I learn more about changing or cancelling my trip in the area near Lake Issaqueena?
For more details about updating your stay near Lake Issaqueena or cancelling it, head over to our customer service page.
What can I see and do near Lake Issaqueena?
You'll want to browse the exhibits at Fort Hill and Clemson Area African American Museum. Explore nature at Keowee Reservoir and Larry W. Abernathy Waterfront Park. If you've got some time to explore the area around Lake Issaqueena, you may want to make a stop by Littlejohn Coliseum, Memorial Stadium, and Sloan Tennis Center.