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Our top choices for Mayo Clinic Scottsdale hotels

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

1. Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3.1 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1,036 reviews)
"Great place to stay, very roomy"
United States
Jose Jr
The price is ₩211,262
₩241,182 total
includes taxes & fees
Nov 18 - Nov 19
Inn at Eagle Mountain
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

2. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
0.3 km from Mayo Clinic Scottsdale
8.4 out of 10, Very good, (1,082 reviews)
"all good happy place to stay"
United States
louis
The price is ₩127,610
₩145,437 total
includes taxes & fees
Nov 22 - Nov 23
Sonesta Select Scottsdale at Mayo Clinic Campus
A modern infinity pool with a view of mountains and a sunset.

3. Talking Stick Resort

Talking Stick Resort
4.0 star property
8.8 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (5,188 reviews)
"I loved staying here!"
United States
Jessica
The price is ₩173,138
₩236,117 total
includes taxes & fees
Nov 22 - Nov 23
Talking Stick Resort
A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

4. Sonesta ES Suites Scottsdale Paradise Valley

Sonesta ES Suites Scottsdale Paradise Valley
3.0 star property
14 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1,004 reviews)
"Friendly staff, good breakfast, dated rooms, clean"
United States
James
The price is ₩150,688
₩171,739 total
includes taxes & fees
Nov 22 - Nov 23
Sonesta ES Suites Scottsdale Paradise Valley
A hotel room with two beds, a television, a desk with a lamp, and artwork on the wall.

5. Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale
2.5 star property
7.6 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (339 reviews)
"Excellent value for a traveler."
United States
Herbert M Beatty
The price is ₩110,206
₩125,822 total
includes taxes & fees
Nov 16 - Nov 17
Spark by Hilton Fountain Hills Scottsdale
An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

6. Hyatt Place Scottsdale - North

Hyatt Place Scottsdale - North
3.0 star property
14.1 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (1,295 reviews)
"Clean rooms, friendly staff, good breakfast spread."
United States
Ted
The price is ₩177,161
₩201,910 total
includes taxes & fees
Nov 22 - Nov 23
Hyatt Place Scottsdale - North
A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

7. Embassy Suites by Hilton Phoenix Scottsdale

Embassy Suites by Hilton Phoenix Scottsdale
3.5 star property
17.8 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1,033 reviews)
"Enjoyed my stay overall everything was great"
United States
Matthew
The price is ₩182,563
₩206,424 total
includes taxes & fees
Nov 22 - Nov 23
Embassy Suites by Hilton Phoenix Scottsdale
A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.

8. Hilton North Scottsdale At Cavasson

Hilton North Scottsdale At Cavasson
4.0 star property
13.4 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (679 reviews)
"Great staff all around the property. Rooms are large, clean and comfortable."
United States
Andrea
The price is ₩252,708
₩288,012 total
includes taxes & fees
Nov 23 - Nov 24
Hilton North Scottsdale At Cavasson
A spacious living area with a kitchen, modern furniture, and a fireplace.

9. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.3 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1,002 reviews)
"The location to family was perfect. We used the work out facilities and enjoyed many near by restaurants. We've stayed at this property several times throughout the past 15 years. The price point is perfect for our needs."
United States
Laura
The price is ₩161,548
₩184,439 total
includes taxes & fees
Dec 6 - Dec 7
Fountain Park Hotel, BW Signature Collection
An outdoor dining table set with chairs, string lights, and a sunset view.

10. Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
4.0 star property
14.8 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (928 reviews)
"Clean room, nice outdoor pool"
Canada
Claudia
The price is ₩189,242
₩216,247 total
includes taxes & fees
Nov 22 - Nov 23
Home2 Suites by Hilton Mesa Longbow, AZ
A conference room with multiple tables and chairs, a sign for Daubs, and a sign for restrooms.

11. Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.3 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1,003 reviews)
"Great stay"
United States
Joshua
The price is ₩114,713
₩171,408 total
includes taxes & fees
Nov 29 - Nov 30
Wekopa Casino Resort
A restaurant setting with round tables, chairs, and empty wine glasses.

12. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1,214 reviews)
"Great breakfast and served until 10:00 a.m. all days; could sleep in."
United States
Marie
The price is ₩133,515
₩152,167 total
includes taxes & fees
Nov 23 - Nov 24
Aiden by Best Western Scottsdale North
A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

13. Courtyard Scottsdale Salt River

Courtyard Scottsdale Salt River
3.5 star property
12.2 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (1,000 reviews)
"Very nice stay the staff are super friendly and helpful"
United States
Karl
The price is ₩160,394
₩182,801 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard Scottsdale Salt River
A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

14. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Holiday Inn & Suites Scottsdale North - Airpark by IHG
3.5 star property
9.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (936 reviews)
"Clean room and helpful staff. Definitely would stay again"
United States
Ally Marie
The price is ₩172,409
₩196,494 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn & Suites Scottsdale North - Airpark by IHG
A modern hotel with a brick facade, large windows, and a covered entrance area.

15. Springhill Suites Phoenix Scottsdale Marriott

Springhill Suites Phoenix Scottsdale Marriott
2.0 star property
18.2 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (468 reviews)
"Centrally located. Nice stay for family."
United States
Lucinda
The price is ₩137,316
₩156,499 total
includes taxes & fees
Nov 22 - Nov 23
Springhill Suites Phoenix Scottsdale Marriott
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

16. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.8 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (2,003 reviews)
"Very comfortable stay"
United States
Laura
The price is ₩137,113
₩156,679 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Place Phoenix/Mesa
An outdoor lounge area with white sofas, a fire pit, and a pool in the background.

17. AC Hotel by Marriott Scottsdale North

AC Hotel by Marriott Scottsdale North
3.5 star property
Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (537 reviews)
"Great hotel in a perfect location."
United States
Stan
The price is ₩175,572
₩198,520 total
includes taxes & fees
Nov 23 - Nov 24
AC Hotel by Marriott Scottsdale North
A modern dining area with multiple tables and chairs, a fireplace, and a television mounted on the wall.

18. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.6 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (2,073 reviews)
"would definitely stay here again"
United States
LAURA
The price is ₩139,285
₩158,813 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Suites Scottsdale Talking Stick Entertainment District
A Courtyard by Marriott hotel with a landscaped entrance featuring a small waterfall and rock formations.

19. Courtyard by Marriott Scottsdale North

Courtyard by Marriott Scottsdale North
3.0 star property
13.6 km from Mayo Clinic Scottsdale
8.6 out of 10, Excellent, (1,002 reviews)
"Quiet, clean, comfortable and good customer service"
United States
Jennifer
The price is ₩148,855
₩168,311 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard by Marriott Scottsdale North
An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

20. Home2 Suites by Hilton Scottsdale North

Home2 Suites by Hilton Scottsdale North
3.0 star property
15 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (832 reviews)
"Very nice place conveniently located. Plenty of parking great staff"
United States
Susan
The price is ₩156,933
₩178,856 total
includes taxes & fees
Nov 22 - Nov 23
Home2 Suites by Hilton Scottsdale North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Mayo Clinic Scottsdale

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

Inn at Eagle Mountain

3.5 star property
3.1 km from Mayo Clinic Scottsdale
View
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

Sonesta Select Scottsdale at Mayo Clinic Campus

3.0 star property
0.3 km from Mayo Clinic Scottsdale
View
A modern infinity pool with a view of mountains and a sunset.

Talking Stick Resort

4.0 star property
8.8 km from Mayo Clinic Scottsdale
View
A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

Sonesta ES Suites Scottsdale Paradise Valley

3.0 star property
14 km from Mayo Clinic Scottsdale
View
A hotel room with two beds, a television, a desk with a lamp, and artwork on the wall.

Spark by Hilton Fountain Hills Scottsdale

2.5 star property
7.6 km from Mayo Clinic Scottsdale
View
9.0
Wonderful
1,036 reviews
8.4
Very good
1,082 reviews
9.4
Exceptional
5,188 reviews
9.2
Wonderful
1,004 reviews
8.8
Excellent
339 reviews
The price is ₩211,262
₩241,182 total
includes taxes & fees
Nov 18 - Nov 19
The price is ₩127,610
₩145,437 total
includes taxes & fees
Nov 22 - Nov 23
The price is ₩173,138
₩236,117 total
includes taxes & fees
Nov 22 - Nov 23
The price is ₩150,688
₩171,739 total
includes taxes & fees
Nov 22 - Nov 23
The price is ₩110,206
₩125,822 total
includes taxes & fees
Nov 16 - Nov 17
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking

Top Mayo Clinic Scottsdale Hotel Reviews

A living room with a sofa, a coffee table, and a kitchen area with a refrigerator and microwave.
Starlite Motel

Starlite Motel

Starlite Motel
Central Mesa

10/10 Excellent

Very comfortable and it had everything I needed to make breakfast and get a good night rest.
United States
Virginia
Reviewed October 1, 2026
Starlite Motel

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.