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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.
A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.
Lobby lounge
A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
0.3 km from Mayo Clinic Scottsdale
United States
Michael
₩143,408
₩163,441 total
includes taxes & fees
Oct 13 - Oct 14
Sonesta Select Scottsdale at Mayo Clinic Campus
A cluster of modern, multi-story buildings with a river in the foreground.
A golf course with a pond, a clubhouse, and a hilly backdrop.
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.
An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

Inn at Eagle Mountain
3.1 km from Mayo Clinic Scottsdale
United States
Shelby
₩177,488
₩202,638 total
includes taxes & fees
Oct 25 - Oct 26
Inn at Eagle Mountain
A hotel lobby with a reception desk, seating area, and a large wall mural.
A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.
A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.
A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale
United States
Paul
₩112,783
₩128,544 total
includes taxes & fees
Oct 25 - Oct 26
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
Pool
A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.
A reception area with a stone wall, a wooden reception desk, and a modern elevator.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
9.6 km from Mayo Clinic Scottsdale
United States
LAURA
₩145,954
₩166,418 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Suites Scottsdale Talking Stick Entertainment District
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.
A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.
A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.
A bar area with a bar counter, multiple chairs, and a sofa.

5. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
8.7 km from Mayo Clinic Scottsdale
United States
Ioana G
₩134,991
₩153,850 total
includes taxes & fees
Oct 12 - Oct 13
Aiden by Best Western Scottsdale North
An outdoor dining table set with chairs, string lights, and a sunset view.
A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.
A modern lobby with a seating area, a kitchen, and a reception desk.
A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

6. Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
14.8 km from Mayo Clinic Scottsdale
United States
Damon
₩207,338
₩236,926 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton Mesa Longbow, AZ
A spacious living area with a kitchen, modern furniture, and a fireplace.
A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.
A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.
A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

7. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
7.3 km from Mayo Clinic Scottsdale
United States
Guadalupe
₩131,493
₩150,125 total
includes taxes & fees
Oct 11 - Oct 12
Fountain Park Hotel, BW Signature Collection
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.
A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.
A bar area with a long counter, multiple stools, and overhead pendant lighting.
A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

8. Hyatt House North Scottsdale

Hyatt House North Scottsdale
14.1 km from Mayo Clinic Scottsdale
United States
Slyqavious
₩180,935
₩206,211 total
includes taxes & fees
Oct 21 - Oct 22
Hyatt House North Scottsdale
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.
A modern hotel with a covered entrance, multiple floors, and a parking lot.
A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.
A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

9. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
17.8 km from Mayo Clinic Scottsdale
United States
greg
₩180,935
₩206,755 total
includes taxes & fees
Oct 29 - Oct 30
Hyatt Place Phoenix/Mesa
A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.
An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.
A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.
A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

10. Embassy Suites by Hilton Phoenix Scottsdale

Embassy Suites by Hilton Phoenix Scottsdale
17.8 km from Mayo Clinic Scottsdale
United States
Jack
₩207,713
₩234,862 total
includes taxes & fees
Oct 18 - Oct 19
Embassy Suites by Hilton Phoenix Scottsdale
A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".
A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.
An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.
A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

11. Tru By Hilton Scottsdale Salt River

Tru By Hilton Scottsdale Salt River
8.9 km from Mayo Clinic Scottsdale
United States
Colleen
₩152,656
₩174,058 total
includes taxes & fees
Nov 8 - Nov 9
Tru By Hilton Scottsdale Salt River
A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.
A modern bar area with seating, a digital menu display, and a beverage refrigerator.
A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.
A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

12. Courtyard Scottsdale Salt River

Courtyard Scottsdale Salt River
12.2 km from Mayo Clinic Scottsdale
United States
Karl
₩195,678
₩223,014 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard Scottsdale Salt River
A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.
A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.
A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.
An outdoor patio area with stone pillars, fire pit seating, and tables.

13. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale
United States
Dana
₩217,591
₩247,989 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.
A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.
A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.
A reception area with a blue counter, a television screen, and a modern interior design.

14. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Holiday Inn & Suites Scottsdale North - Airpark by IHG
9.7 km from Mayo Clinic Scottsdale
United States
Ally Marie
₩202,379
₩230,651 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn & Suites Scottsdale North - Airpark by IHG
A modern bar area with a long counter, multiple stools, and large windows offering a view of the outdoor garden.
A poolside area with lounge chairs, a pool, palm trees, and a covered seating area with curtains.
A hotel lobby with a reception area, seating, and a view of the outdoor garden.
An outdoor patio area with tables and chairs, surrounded by potted plants and palm trees.

15. Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham
18.4 km from Mayo Clinic Scottsdale
United States
Kat
₩143,542
₩163,606 total
includes taxes & fees
Oct 11 - Oct 12
Papago Scottsdale by Reside, Trademark Collection by Wyndham
A hotel pool area with sun loungers, a children's play area, and a building with a sign.
A modern kitchen with a central island, bar stools, and a sign that reads "inspired table".
A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.
A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

16. Home2 Suites by Hilton Scottsdale Salt River

Home2 Suites by Hilton Scottsdale Salt River
9.6 km from Mayo Clinic Scottsdale
United States
Felipe
₩174,743
₩199,242 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton Scottsdale Salt River
A modern hotel with a brick facade, large windows, and a covered entrance area.
An outdoor patio area with round tables and chairs, a fire pit, and a large umbrella.
A hotel room with a desk, two beds, a TV, and a large window.
A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.

17. Springhill Suites Phoenix Scottsdale Marriott

Springhill Suites Phoenix Scottsdale Marriott
18.2 km from Mayo Clinic Scottsdale
United States
Marie
₩159,062
₩181,282 total
includes taxes & fees
Oct 18 - Oct 19
Springhill Suites Phoenix Scottsdale Marriott
A hotel pool area with lounge chairs, a hot tub, and a building with balconies.
A motel sign with the number 6, surrounded by palm trees and a clear blue sky.
A hotel room with a bed, a desk, a chair, and a mirror.
A motel with a prominent '6' sign, a parking lot, and palm trees.

18. Motel 6 Old town Scottsdale/Fashion Square

Motel 6 Old town Scottsdale/Fashion Square
Fashion Square, 15.9 km from Mayo Clinic Scottsdale
United States
Kayla
₩107,194
₩122,178 total
includes taxes & fees
Oct 12 - Oct 13
Motel 6 Old town Scottsdale/Fashion Square
An outdoor lounge area with white sofas, a fire pit, and a pool in the background.
A modern hotel lobby with a long seating area, a reception desk, and large windows providing natural light.
A modern kitchen with a bar area, bar stools, and a dining table with chairs.
A spacious hotel lobby with modern furniture, large windows, and a flat-screen TV.

19. AC Hotel by Marriott Scottsdale North

AC Hotel by Marriott Scottsdale North
Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale
United States
Kristen
₩231,436
₩261,686 total
includes taxes & fees
Oct 31 - Nov 1
AC Hotel by Marriott Scottsdale North
An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.
A bar area with a long counter, multiple bar stools, and overhead lighting.
A hotel room with two beds, a desk, a sofa, and a TV.
A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

20. Hyatt Place North Scottsdale

Hyatt Place North Scottsdale
14.1 km from Mayo Clinic Scottsdale
United States
Ted
₩174,900
₩199,333 total
includes taxes & fees
Oct 25 - Oct 26
Hyatt Place North Scottsdale
View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.
Sonesta Select Scottsdale at Mayo Clinic Campus
8.4
Very good
1,084 reviews
View
A cluster of modern, multi-story buildings with a river in the foreground.
Inn at Eagle Mountain
9.0
Wonderful
1,026 reviews
View
A hotel lobby with a reception desk, seating area, and a large wall mural.
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
8.8
Excellent
1,856 reviews
View
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
Comfort Suites Scottsdale Talking Stick Entertainment District
9.2
Wonderful
2,043 reviews
View
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.
Aiden by Best Western Scottsdale North
9.0
Wonderful
1,175 reviews
View

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

Talking Stick Resort

10/10 Excellent
"Best stay forever! Smoke free gaming areas, comedy show was great!"
Mark 2-night trip
Posted less than an hour ago
Talking Stick Resort
Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent
"Clean room. Clean place. Comfy bed"
Javier 2-night trip
Posted 16 hours ago
Comfort Suites Scottsdale Talking Stick Entertainment District
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent
"We wouldn't hesitate to stay here again. The room was clean and aesthetically pleasing, and the staff were super nice. When we called about a toilet issue, a maintenance person was sent up quickly and resolved the problem. We saw the spacious gym but didn't use it. Breakfast was excellent. All in all, we really enjoyed our stay."
P 4-night trip
Posted 19 hours ago
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Inn at Eagle Mountain

Inn at Eagle Mountain

10/10 Excellent
"Wonderful staff!!"
Richard 2-night trip
Posted 22 hours ago
Inn at Eagle Mountain
ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent
"Our stay was wonderful. A few high points: - The staff were friendly and helpful. Jasmine, for one, at the front desk was very responsive. - Dom and Keri in the spa were especially wonderful (as was our masseuse). Can't wait to come back to the spa (hopefully next year?). Lots of great services available there. - Housekeeping was efficient and did a great job. - The resort was beautiful and quiet with a terrific view. Perfect for what our needs were. - The surrounding community, while not walkable, has plenty of restaurants and shopping close by (check out Fountain Hills, it's a nice alternative to Scottsdale, the fountain is cool!). I hope we can go back again (I really didn't want to leave!)."
Kevin 6-night trip
Posted 1 day ago
ADERO Scottsdale Resort, Autograph Collection
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent
"I had a quiet stay which allowed me to rest well and appreciated the cool pool"
Virginia 2-night trip
Posted 2 days ago
Sonesta Select Scottsdale at Mayo Clinic Campus
Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent
"It was a comfortable stay."
Herlyn 1-night trip
Posted 5 days ago
Spark by Hilton Fountain Hills Scottsdale

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I be able to find close to Mayo Clinic Scottsdale?
Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.