Top Mission District Hotels

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels in Mission District

Property	Property class	Guest rating
Noe's Nest Bed and Breakfast	3.5 star property	9.4 Exceptional 132 reviews	View
Parker Guest House San Francisco	3.5 star property	9.6 Exceptional 485 reviews	View
1906 Mission	2.0 star property	8.0 Very Good 197 reviews	View
Union Hotel	2.0 star property	7.0 Good 312 reviews	View
Hotel Sunrise	2.0 star property	6.8 661 reviews	View

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

See properties

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

See properties

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

See properties

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

See properties

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

See properties

Top Mission District Hotel Reviews

Handlery Union Square Hotel

8/10 Good

"Clean and ideally located. The room faced the pool and so it was occasionally noisy. We did not use the pool or fitness centre or spa or parking. The fitness centre equipment, however, looked rudimentary. Likewise the breakfast box- there is no bar or meal activity here but the area is replete with cafes and restaurants, some offering 10% discounts to patrons of the hotel. It is a basic hotel with helpful staff."

Chancellor Hotel on Union Square

10/10 Excellent

"Affordable and comfortable, with friendly staff and a great location. The hotel is a bit on the older side, but it’s kept clean overall. They go the extra mile by offering not only water, coffee, and tea, but also tasty cookies and apples in the lobby. Small touches like these can make a big difference when you're traveling. The room felt a little stiff, but opening the window for a few hours helped improve the airflow. Since my room faces a busy street, I could hear the noise from nearby events, so bringing earplugs might be a good idea if you're a light sleeper. Overall, I’d recommend this hotel for budget travelers and would happily stay here again."

Frequently asked questions

What is Mission District like?

Mission District is a neighborhood that travelers like for its bars. Are you looking for Mission District travel tips? Be sure to check out Southern Exposure and San Francisco Public Library while you're in the neighborhood.

Where is the best place to stay in Mission District?

Based on Expedia customer reviews, Parker Guest House San Francisco is the highest ranked property in Mission District. This B&B offers free breakfast and free WiFi. Other top choices in the neighborhood include Noe's Nest Bed and Breakfast and 1906 Mission.

How many hotels should I expect to find in the Mission District area?

Expedia has 65 hotels and other accommodations in Mission District to choose from, making this an ideal home base for exploring the greater San Francisco area.

If I need to cancel my hotel reservation in Mission District, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals in Mission District.

Where can I learn more about changing or cancelling my trip to Mission District?

To access more information about rescheduling or cancelling your trip to Mission District, click here.

What are the top things to see and do in Mission District?

Mission District's sights and attractions like Marsh Theater, Victoria Theatre, and Creativity Explored offer insight into the local culture. Southern Exposure and San Francisco Public Library are also a couple of places to visit in the neighborhood. Oracle Park, The Chapel, and Paxton Gate are just a few of the places to visit in and around Mission District. While you're out sightseeing in San Francisco, be sure to visit other sights like Incline Gallery or Mission Bowling Club.

How can I get around Mission District and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at 16th Street Mission Station, 24th Street Mission Station, or Right Of Way/20th St Stop.

Find hotels in Mission District, San Francisco

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Mission District hotels

Noe's Nest Bed and Breakfast

Parker Guest House San Francisco

1906 Mission

Union Hotel

Hotel Sunrise

Marin Lodge

The Evergreen

Hotel Riu Plaza Fisherman's Wharf

LUMA Hotel San Francisco

Hilton San Francisco Airport Bayfront

Hotel Caza Fisherman's Wharf

Marina Village Inn

The Marina Inn on San Francisco Bay

Stanyan Park Hotel

Hotel Zephyr San Francisco

Hotel Shattuck Plaza

Cow Hollow Inn & Suites

Aloft by Marriott San Francisco Airport

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Star Motel

Compare popular hotels in Mission District

Where to stay in Mission District

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Mission District Hotel Reviews

Handlery Union Square Hotel

Frequently asked questions

Explore a world of travel with Expedia